Search Results - "Huis‐Tanja, Lieke H."

The impact of surgery and adjuvant chemotherapy on health‐related quality of life in patients with colon cancer: Changes at group level versus individual level by Scheepers, Ellen R. M., Vink, Geraldine R., Schiphorst, Anandi H. W., Emmelot‐Vonk, Marielle H., Huis‐Tanja, Lieke H., Hamaker, Marije E.

“…Objective This study aims to evaluate changes in health‐related quality of life (HR‐QoL) 1 year after surgical treatment in patients with primary resectable…”
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The G8 frailty screening tool and the decision‐making process in older breast cancer patients by Scheepers, Ellen R. M., Molen, Loes F., Bos, Frederiek, Burgmans, Josephine P., Huis‐Tanja, Lieke H., Hamaker, Marije E.

“…Objective To assess the decision‐making process in fit and frail older breast cancer patients. Methods Breast cancer patients aged ≥70 years who completed the…”
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Chemotherapy in the oldest old: Choices and outcomes by van Walree, Inez Charlotte, Breukelen, Eline L. G., Thielen, Noortje, Rens, Marcel T. M., Huis‐Tanja, Lieke H., Hamaker, Marije E.

“…Treatment decision‐making in older patients with cancer is difficult due to a paucity of data evaluating chemotherapy tolerability in this population. We…”
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Severe fluoropyrimidine toxicity due to novel and rare DPYD missense mutations, deletion and genomic amplification affecting DPD activity and mRNA splicing by van Kuilenburg, André B.P., Meijer, Judith, Maurer, Dirk, Dobritzsch, Doreen, Meinsma, Rutger, Los, Maartje, Knegt, Lia C., Zoetekouw, Lida, Jansen, Rob L.H., Dezentjé, Vincent, van Huis-Tanja, Lieke H., van Kampen, Roel J.W., Hertz, Jens Michael, Hennekam, Raoul C.M.

“…Dihydropyrimidine dehydrogenase (DPD) is the initial and rate-limiting enzyme in the catabolism of 5-fluorouracil (5FU). Genetic variations in DPD have emerged…”
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Optimizing the geriatrician's contribution to cancer care for older patients by Hamaker, Marije E., van Huis-Tanja, Lieke H., Rostoft, Siri

“…Cancer specialists and geriatricians can struggle to find the best form for their collaboration within geriatric oncology and do not always benefit optimally…”
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What Defines Quality of Life for Older Patients Diagnosed with Cancer? A Qualitative Study by Seghers, Petronella A L Nelleke, Kregting, Jolina A, van Huis-Tanja, Lieke H, Soubeyran, Pierre, O'Hanlon, Shane, Rostoft, Siri, Hamaker, Marije E, Portielje, Johanneke E A

“…The treatment of cancer can have a significant impact on quality of life in older patients and this needs to be taken into account in decision making. However,…”
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Clinical judgment versus geriatric assessment for frailty in older patients with cancer by van Walree, Inez C., Scheepers, Ellen R.M., van den Bos, Frederiek, van Huis-Tanja, Lieke H., Emmelot-Vonk, Marielle H., Hamaker, Marije E.

“…Geriatric assessment (GA) is an appropriate method for identifying frailty in older patients with cancer, but a shorter instrument may be easier to use in…”
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Development of a self-reported version of the G8 screening tool by van Walree, Inez Charlotte, Vondeling, Ariel M, Vink, Geraldine R, van Huis-Tanja, Lieke H, Emmelot-Vonk, Marielle H, Bellera, Carine, Soubeyran, Pierre, Hamaker, Marije E

“…AbstractIntroductionThe G8 is a widely used frailty screening tool in patients with cancer that was designed to be completed by healthcare professionals. A…”
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Factors associated with survival in older patients with stage I-III colorectal carcinoma who were not managed curatively in the Netherlands by Vondeling, Ariël M., Hazen, Josje C.E.P., van Huis-Tanja, Lieke H., Schiphorst, Anandi H.W., van der Bol, Jessica, Dekker, Jan Willem, Hamaker, Marije E.

“…Some patients with stage I-III colorectal cancer (CRC) do not undergo tumor resection. Little is known about survival of these non-curatively managed patients…”
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Do age and comorbidity impair recovery during two years after treatment for endometrial cancer? by van Walree, Inez C., Hamaker, Marije E., de Rooij, Belle H., Boll, Dorry, van Huis-Tanja, Lieke H., Emmelot-Vonk, Marielle H., Ezendam, Nicole P.M.

“…A better understanding of the impact of age and comorbidity on health-related quality of life (HRQoL) may improve treatment decision-making in patients with…”
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MTHFR polymorphisms and capecitabine-induced toxicity in patients with metastatic colorectal cancer by van Huis-Tanja, Lieke H, Gelderblom, Hans, Punt, Cornelis J.A, Guchelaar, Henk-Jan

“…OBJECTIVEThe availability of current chemotherapeutic options for metastatic colorectal cancer (mCRC) has increased survival, but it is also accompanied by…”
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Clinical validation study of genetic markers for capecitabine efficacy in metastatic colorectal cancer patients by van Huis-Tanja, Lieke H, Ewing, Ewoud, van der Straaten, R.J.H.M, Swen, Jesse J, Baak-Pablo, Renée F, Punt, C.J.A, Gelderblom, A.J, Guchelaar, Henk-Jan

“…BACKGROUND AND AIMPharmacogenetic studies continue to search for pretreatment predictors of chemotherapeutic efficacy and toxicity in metastatic colorectal…”
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Trends in Use and Perceptions About Triplet Chemotherapy Plus Bevacizumab for Metastatic Colorectal Cancer by van Nassau, Sietske C, Bond, Marinde J, Scheerman, Ilva, van Breeschoten, Jesper, Kessels, Rob, Valkenburg-van Iersel, Liselot B, Verheul, Henk M, Buffart, Tineke E, Mekenkamp, Leonie J, Lemmens, Valery E, Koopman, Miriam, Bol, Guus M

“…Triplet chemotherapy with fluorouracil, folinic acid, oxaliplatin, and irinotecan plus bevacizumab (FOLFOXIRI-B) is an effective first-line treatment option…”
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Excision Repair Cross-Complementation group 1 (ERCC1) C118T SNP does not affect cellular response to oxaliplatin by van Huis-Tanja, Lieke H, Kweekel, Dina M, Lu, Xiaobo, Franken, Kees, Koopman, Miriam, Gelderblom, Hans, Antonini, Ninja F, Punt, Cornelis J A, Guchelaar, Henk-Jan, van der Straaten, Tahar

“…ERCC1 is involved in the repair of oxaliplatin-induced DNA damage. Studies for the association of the C118T SNP with clinical response to treatment with…”
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Quality of Life and Survival of Metastatic Colorectal Cancer Patients Treated With Trifluridine-Tipiracil (QUALITAS) by Hamers, Patricia A.H., Vink, Geraldine R., Elferink, Marloes A.G., Stellato, Rebecca K., Dijksterhuis, Willemieke P.M., Punt, Cornelis J.A., Koopman, Miriam, May, Anne M., Beerepoot, Laurens V., Creemers, Geert-Jan, van Cruijsen, Hester, de Groot, Jan Willem B., van Halteren, Henk K., Helgason, Helgi H., Hendriks, Mathijs P., Hoekstra, Ronald, van Huis-Tanja, Lieke H., Kapiteijn, Ellen, Los, Maartje, van Meerten, Esther, Peters, Natascha A.J.B., Pruijt, Johannes F.M., van Ufford-Mannesse, Patricia Quarles, Sie, Mark P.S., Sommeijer, Dirkje W., Spierings, Leontine E.A.M.M., Terheggen, Frederiek, Tjin-A-Ton, Manuel L.R., Valkenburg-van Iersel, Liselot B.J., van Voorthuizen, Theo, de Vos-Geelen, Judith, Vulink, Annelie J.E., J van de Wouw, Agnès

“…The RECOURSE trial demonstrated a modest benefit in overall survival (OS) for trifluridine/tipiracil (FTD/TPI) versus placebo in pretreated metastatic…”
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