Search Results - "Hui‐Chun Ho, Jennifer"

Oscillatory Shear Stress Mediates Directional Reorganization of Actin Cytoskeleton and Alters Differentiation Propensity of Mesenchymal Stem Cells by Kuo, Yi‐Chun, Chang, Tzu‐Hao, Hsu, Wei‐Tse, Zhou, Jing, Lee, Hsiao‐Hui, Hui‐Chun Ho, Jennifer, Chien, Shu, Kuang‐Sheng, Oscar

“…Shear stress stimuli differentially regulate cellular functions based on the pattern, magnitude as well as duration of the flow. Shear stress can modify…”
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Mesenchymal stem cells prolong survival and prevent lethal complications in a porcine model of fulminant liver failure by Lin, Niang‐Cheng, Wu, Hao‐Hsiang, Ho, Jennifer Hui‐Chun, Liu, Chin‐Su, Lee, Oscar Kuang‐Sheng

“…Background Fulminant liver failure (FLF) is a life‐threatening disease. Methods Lethal FLF was induced by ischemia‐reperfusion (I‐R) injury in mini‐pigs, and…”
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Performance and Limitation of Machine Learning Algorithms for Diabetic Retinopathy Screening: Meta-analysis by Wu, Jo-Hsuan, Liu, T Y Alvin, Hsu, Wan-Ting, Ho, Jennifer Hui-Chun, Lee, Chien-Chang

“…Background: Diabetic retinopathy (DR), whose standard diagnosis is performed by human experts, has high prevalence and requires a more efficient screening…”
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Regulation of the fate of human mesenchymal stem cells by mechanical and stereo-topographical cues provided by silicon nanowires by Kuo, Shu-Wen, Lin, Hsin-I, Hui-Chun Ho, Jennifer, Shih, Yu-Ru V, Chen, How-Foo, Yen, Ta-Jen, Lee, Oscar K

“…Abstract Extracellular stimuli imposed on stem cells enable efficient initiation of mechanotransductive signaling to regulate stem cell fates; however, how…”
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Treatment of Spinocerebellar Ataxia with Mesenchymal Stem Cells: A Phase I/IIa Clinical Study by Tsai, Yun-An, Liu, Ren-Shyan, Lirng, Jiing-Feng, Yang, Bang-Hung, Chang, Chin-Hao, Wang, Yi-Chen, Wu, Yu-Shan, Ho, Jennifer Hui-Chun, Lee, Oscar K., Soong, Bing-Wen

“…Ataxia is one of the most devastating symptoms of many neurodegenerative disorders. As of today, there is not any effective treatment to retard its…”
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Modulation of experimental acute lung injury by exosomal miR-7704 from mesenchymal stromal cells acts through M2 macrophage polarization by Lin, Wei-Ting, Wu, Hao-Hsiang, Lee, Chien-Wei, Chen, Yu-Fan, Huang, Lawrence, Hui-Chun Ho, Jennifer, Kuang-Sheng Lee, Oscar

“…Acute lung injury (ALI) is a life-threatening condition with limited treatment options. The pathogenesis of ALI involves macrophage-mediated disruption and…”
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Mesenchymal stem cells restore the sperm motility from testicular torsion-detorsion injury by regulation of glucose metabolism in sperm by Hsiao, Chi-Hao, Ji, Andrea Tung-Qian, Chang, Chih-Cheng, Chien, Ming-Hsien, Lee, Liang-Ming, Ho, Jennifer Hui-Chun

“…Testicular torsion is an urological emergency that may lead to infertility due to ischemic injury. Promptly surgical correction by orchiopexy is the only way…”
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Control of matrix stiffness promotes endodermal lineage specification by regulating SMAD2/3 via lncRNA LINC00458 by Chen, Yu-Fan, Li, Yi-Shuan J, Chou, Chih-Hung, Chiew, Men Yee, Huang, Hsien-Da, Ho, Jennifer Hui-Chun, Chien, Shu, Lee, Oscar K

“…During endoderm formation, cell identity and tissue morphogenesis are tightly controlled by cell-intrinsic and cell-extrinsic factors such as biochemical and…”
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Targeting Dual Immune Checkpoints PD‐L1 and HLA‐G by Trispecific T Cell Engager for Treating Heterogeneous Lung Cancer by Lin, Yu‐Chuan, Chen, Mei‐Chih, Huang, Shi‐Wei, Chen, Yeh, Ho, Jennifer Hui‐Chun, Lin, Fang‐Yu, Tan, Xiao‐Tong, Chiang, Hung‐Che, Huang, Chiu‐Ching, Tu, Chih‑Yen, Cho, Der‐Yang, Chiu, Shao‐Chih

“…Immunotherapy targeting immune checkpoints (ICPs), such as programmed death‐ligand‐1 (PD‐L1), is used as a treatment option for advanced or metastatic…”
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Stromal Tissue Rigidity Promotes Mesenchymal Stem Cell‐Mediated Corneal Wound Healing Through the Transforming Growth Factor β Signaling Pathway by Yang, Yun‐Hsiang, Hsieh, Ting‐Lieh, Ji, Andrea Tung‐Qian, Hsu, Wei‐Tse, Liu, Chia‐Yu, Lee, Oscar Kuang‐Sheng, Ho, Jennifer Hui‐Chun

“…The healing of a corneal epithelial defect is essential for preventing infectious corneal ulcers and subsequent blindness. We previously demonstrated that…”
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Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection by Ho, Jennifer Hui-Chun, Hong, Chuang-Ye

“…Salvianolic acids are the most abundant water-soluble compounds extracted from Radix Salvia miltiorrhiza (Danshen). In China, Danshen has been wildly used to…”
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DAS181 Treatment of Severe Lower Respiratory Tract Parainfluenza Virus Infection in Immunocompromised Patients: A Phase 2 Randomized, Placebo-Controlled Study by Chemaly, Roy F, Marty, Francisco M, Wolfe, Cameron R, Lawrence, Steven J, Dadwal, Sanjeet, Soave, Rosemary, Farthing, Jason, Hawley, Stephen, Montanez, Paul, Hwang, Jimmy, Ho, Jennifer, Lewis, Stanley, Wang, George, Boeckh, Michael

“…There are no antiviral therapies for Parainfluenza virus (PIV) infections. DAS181, a sialidase fusion protein, has demonstrated activity in in vitro and in…”
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Three-dimensional spherical spatial boundary conditions differentially regulate osteogenic differentiation of mesenchymal stromal cells by Lo, Yin-Ping, Liu, Yi-Shiuan, Rimando, Marilyn G., Ho, Jennifer Hui-Chun, Lin, Keng-hui, Lee, Oscar K.

“…The spatial boundary condition (SBC) arising from the surrounding microenvironment imposes specific geometry and spatial constraints that affect organogenesis…”
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Comparative analysis of medical treatments for long-term control of normal tension glaucoma: A systematic review and model-based network meta-analysis by Yang, Ting-Kai, Kuo, Hou-Ting, Ju, Yuh-Jen, Chen, Chun-Yi, Chen, Wen-Hsien, Wu, Albert Y, Lin, Chun-Ju, Lee, Chien-Chang, Ho, Jennifer Hui-Chun

“…To evaluate and compare the long-term efficacy of medical treatments for normal tension glaucoma (NTG) in controlling intraocular pressure (IOP), and establish…”
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Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization by Chen, Wei-Ta, Hsu, Wei-Tse, Yen, Meng-Hua, Changou, Chun A., Han, Chia-Li, Chen, Yu-Ju, Cheng, Ji-Yen, Chang, Tzu-Hao, Lee, Oscar Kuang-Sheng, Ho, Jennifer Hui-Chun

“…Mesenchymal stem cell (MSC) is mechanosensitive and the respond to mechanical force is pattern specific. We previously reported that oscillatory shear stress…”
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Clinical Efficacy of Omidenepag Isopropyl for Primary Open-Angle Glaucoma, Normal Tension Glaucoma, or Ocular Hypertension: A Meta-Analysis by Kuo, Hou-Ting, Yeh, Cyuan-Yi, Hsu, Alan Y, Ho, Jennifer Hui-Chun, Lin, Chun-Ju, Tsai, Yi-Yu

“…To investigate the clinical efficacy of omidenepag isopropyl (OMDI) among glaucoma patients in terms of increased intraocular pressure (IOP) changes through a…”
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The activation of directional stem cell motility by green light-emitting diode irradiation by Ong, Wei-Kee, Chen, How-Foo, Tsai, Cheng-Ting, Fu, Yun-Ju, Wong, Yi-Shan, Yen, Da-Jen, Chang, Tzu-Hao, Huang, Hsien-Da, Kuang-Sheng Lee, Oscar, Chien, Shu, Hui-Chun Ho, Jennifer

“…Abstract Light-emitting diode (LED) irradiation is potentially a photostimulator to manipulate cell behavior by opsin-triggered phototransduction and thermal…”
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Ankylosing spondylitis and the risk of cancer by Chang, Chih-Cheng, Chang, Cheng-Wei, Nguyen, Phung-Anh Alex, Chang, Tzu-Hao, Shih, Ya-Ling, Chang, Wen-Ying, Horng, Jorng-Tzong, Lee, Oscar Kuang-Sheng, Ho, Jennifer Hui-Chun

“…Cancer is a multifactorial disease, and imbalances of the immune response and sex-associated features are considered risk factors for certain types of cancer…”
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Efficient generation of hepatic cells from mesenchymal stromal cells by an innovative bio-microfluidic cell culture device by Yen, Meng-Hua, Wu, Yuan-Yi, Liu, Yi-Shiuan, Rimando, Marilyn, Ho, Jennifer Hui-Chun, Lee, Oscar Kuang-Sheng

“…Mesenchymal stromal cells (MSCs) are multipotent and have great potential in cell therapy. Previously we reported the differentiation potential of human MSCs…”
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Cardiovascular protection of magnolol: cell-type specificity and dose-related effects by Ho, Jennifer Hui-Chun, Hong, Chuang-Ye

“…Magnolia officinalis has been widely used in traditional Chinese medicine. Magnolol, an active component isolated from Magnolia officinalis, is known to be a…”
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