Search Results - "Hui, Lim Siang"

In Vitro and In Vivo Photocytotoxicity of Boron Dipyrromethene Derivatives for Photodynamic Therapy by Lim, Siang Hui, Thivierge, Cliferson, Nowak-Sliwinska, Patrycja, Han, Junyan, van den Bergh, Hubert, Wagnières, Georges, Burgess, Kevin, Lee, Hong Boon

“…To understand the effects of substitution patterns on photosensitizing the ability of boron dipyrromethene (BODIPY), two structural variations that either…”
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In Vivo Studies of Nanostructure-Based Photosensitizers for Photodynamic Cancer Therapy by Voon, Siew Hui, Kiew, Lik Voon, Lee, Hong Boon, Lim, Siang Hui, Noordin, Mohamed Ibrahim, Kamkaew, Anyanee, Burgess, Kevin, Chung, Lip Yong

“…Animal models, particularly rodents, are major translational models for evaluating novel anticancer therapeutics. In this review, different types of…”
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Improved photodynamic efficacy of Zn(II) phthalocyanines via glycerol substitution by Chin, Yunni, Lim, Siang Hui, Zorlu, Yunus, Ahsen, Vefa, Kiew, Lik Voon, Chung, Lip Yong, Dumoulin, Fabienne, Lee, Hong Boon

“…Phthalocyanines are excellent photosensitizers for photodynamic therapy as they have strong absorbance in the near infra-red region which is most relevant for…”
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Rosamines targeting the cancer oxidative phosphorylation pathway by Lim, Siang Hui, Wu, Liangxing, Kiew, Lik Voon, Chung, Lip Yong, Burgess, Kevin, Lee, Hong Boon

“…Reprogramming of energy metabolism is pivotal to cancer, so mitochondria are potential targets for anticancer therapy. A prior study has demonstrated the…”
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In vivo study of tetraprenyltoluquinone, an anticancer compounds from Garcinia cowa Roxb by Wahyuni, Fatma Sri, Hui, Lim Siang, Stanslas, Johnson, Lajis, Nordin Hj, D, Dachriyanus

“…Objective: To investigate the in vivo antitumor effect of TPTQ against H-460 lung cancer cell lines in nude mice. Materials and Methods: Female nude mice…”
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New cytotoxic rosamine derivatives selectively accumulate in the mitochondria of cancer cells by Lim, Siang Hui, Wu, Liangxing, Burgess, Kevin, Lee, Hong Boon

“…Conventional cytotoxic anticancer drugs that target all rapidly dividing cells are nonselective in their mechanism of action, because they disrupt essential…”
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BODIPY dyes in photodynamic therapy by Kamkaew, Anyanee, Lim, Siang Hui, Lee, Hong Boon, Kiew, Lik Voon, Chung, Lip Yong, Burgess, Kevin

“…BODIPY dyes tend to be highly fluorescent, but their emissions can be attenuated by adding substituents with appropriate oxidation potentials. Substituents…”
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Biological Evaluation of Curcumin and Related Diarylheptanoids by Abas, Faridah, Hui, Lim Siang, Ahmad, Syahida, Stanslas, Johnson, Israf, D. A., Shaari, Khozirah, Lajis, Nordin H.

“…Nine derivatives of three natural diarylheptanoids, curcumin, demethoxycurcumin and bisdemethoxycurcumin, were prepared. Their antioxidant, free radical…”
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Photodynamic Characterization of Amino Acid Conjugated 151‑Hydroxypurpurin-7-lactone for Cancer Treatment by Lim, Siang Hui, Yam, Mun Li, Lam, May Lynn, Kamarulzaman, Fadzly Azhar, Samat, Norazwana, Kiew, Lik Voon, Chung, Lip Yong, Lee, Hong Boon

“…This study aims to improve the photodynamic properties and biological effectiveness of 151-hydroxypurpurin-7-lactone dimethyl ester (G2), a semisynthetic…”
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A New Naturally Derived Photosensitizer and Its Phototoxicity on Head and Neck Cancer Cells by Lim, Siang Hui, Lee, Hong Boon, Ho, Anthony Siong Hock

“…In our screening for photosensitizers from natural resources, 151‐hydroxypurpurin‐7‐lactone ethyl methyl diester (compound 1) was isolated for the first time…”
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SRJ09, a promising anticancer drug lead: Elucidation of mechanisms of antiproliferative and apoptogenic effects and assessment of in vivo antitumor efficacy by Wong, Charng Choon, Lim, Siang Hui, Sagineedu, Sreenivasa Rao, Lajis, Nordin Haji, Stanslas, Johnson

“…[Display omitted] SRJ09 (3,19-(2-bromobenzylidene)andrographolide), a semisynthetic andrographolide (AGP) derivative, was shown to induce G1 cell cycle arrest…”
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Improved Photodynamic Efficacy of Zn by Chin, Yunni, Lim, Siang Hui, Zorlu, Yunus, Ahsen, Vefa, Kiew, Lik Voon, Chung, Lip Yong, Dumoulin, Fabienne, Lee, Hong Boon

“…Phthalocyanines are excellent photosensitizers for photodynamic therapy as they have strong absorbance in the near infra-red region which is most relevant for…”
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Photodynamic characterization of amino acid conjugated 15(1)-hydroxypurpurin-7-lactone for cancer treatment by Lim, Siang Hui, Yam, Mun Li, Lam, May Lynn, Kamarulzaman, Fadzly Azhar, Samat, Norazwana, Kiew, Lik Voon, Chung, Lip Yong, Lee, Hong Boon

“…This study aims to improve the photodynamic properties and biological effectiveness of 15(1)-hydroxypurpurin-7-lactone dimethyl ester (G2), a semisynthetic…”
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The neovessel occlusion efficacy of 15-hydroxypurpurin-7-lactone dimethyl ester induced with photodynamic therapy by Lim, Siang Hui, Nowak-Sliwinska, Patrycja, Kamarulzaman, Fadzly Adzhar, van den Bergh, Hubert, Wagnières, Georges, Lee, Hong Boon

“…In this study, the photodynamic therapy (PDT) induced efficacy of a semi-synthesized analogue 15(1)-hydroxypurpurin-7-lactone dimethyl ester or G2, in terms of…”
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The Neovessel Occlusion Efficacy of 151-Hydroxypurpurin-7-Lactone Dimethyl Ester Induced with Photodynamic Therapy by Lim, Siang Hui, Nowak-Sliwinska, Patrycja, Kamarulzaman, Fadzly Adzhar, Van Den Bergh, Hubert, Wagnières, Georges, Lee, Hong Boon

“…In this study, the photodynamic therapy (PDT) induced efficacy of a semi‐synthesized analogue 151‐hydroxypurpurin‐7‐lactone dimethyl ester or G2, in terms of…”
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Photodynamic Characterization of Amino Acid Conjugated 15 1 -Hydroxypurpurin-7-lactone for Cancer Treatment by Lim, Siang Hui, Yam, Mun Li, Lam, May Lynn, Kamarulzaman, Fadzly Azhar, Samat, Norazwana, Kiew, Lik Voon, Chung, Lip Yong, Lee, Hong Boon

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Synthesis of damnacanthal, a naturally occurring 9,10-anthraquinone and its analogues, and its biological evaluation against five cancer cell lines by Saha, Koushik, Lam, Kok Wai, Abas, Faridah, Sazali Hamzah, A., Stanslas, Johnson, Hui, Lim Siang, Lajis, Nordin H.

“…Damnacanthal and nordamnacanthal, two naturally occurring 9,10-anthraquinones, and their analogues were synthesized. Cytotoxic activity against five cancer…”
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Andrographolide as a template in the synthesis of new anticancer agents with potentially novel molecular targets by Stanslas, Johnson, Lim, Siang Hui, Wong, Charng Choon, Sagineedu, Sreenivasa Rao, Lajis, Nordin Haji

“…Using andrographolide (AGP) as a template, a series of semisynthetic analogues was synthesised for the discovery of new anticancer agent(s) with improved…”
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Evaluation of 151 -Hydroxypurpurin-7- Lactone (G2) Derivatives, Boron Dipyrromethene (Bodipy) and Rosamine Analogues as Photosensitisers for Photodynamic Cancer Therapy by Hui, Lim Siang

“…Photodynamic therapy (PDT) is a therapeutic strategy that utilises the administration of a photosensitiser along with light irradiation to generate reactive…”
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The Neovessel Occlusion Efficacy of 15 1 ‐Hydroxypurpurin‐7‐Lactone Dimethyl Ester Induced with Photodynamic Therapy by Lim, Siang Hui, Nowak‐Sliwinska, Patrycja, Kamarulzaman, Fadzly Adzhar, Van Den Bergh, Hubert, Wagnières, Georges, Lee, Hong Boon

“…In this study, the photodynamic therapy (PDT) induced efficacy of a semi‐synthesized analogue 15 1 ‐hydroxypurpurin‐7‐lactone dimethyl ester or G2, in terms of…”
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