Search Results - "Hui, Angela Y."

MicroRNA-196b regulates the homeobox B7-vascular endothelial growth factor axis in cervical cancer by How, Christine, Hui, Angela B Y, Alajez, Nehad M, Shi, Wei, Boutros, Paul C, Clarke, Blaise A, Yan, Rui, Pintilie, Melania, Fyles, Anthony, Hedley, David W, Hill, Richard P, Milosevic, Michael, Liu, Fei-Fei

“…The down-regulation of microRNA-196b (miR-196b) has been reported, but its contribution to cervical cancer progression remains to be investigated. In this…”
Get full text

Developing a prognostic micro-RNA signature for human cervical carcinoma by How, Christine, Pintilie, Melania, Bruce, Jeff P, Hui, Angela B Y, Clarke, Blaise A, Wong, Philip, Yin, Shaoming, Yan, Rui, Waggott, Daryl, Boutros, Paul C, Fyles, Anthony, Hedley, David W, Hill, Richard P, Milosevic, Michael, Liu, Fei-Fei

“…Cervical cancer remains the third most frequently diagnosed and fourth leading cause of cancer death in women worldwide. We sought to develop a micro-RNA…”
Get full text

Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues by Hui, Angela B Y, Shi, Wei, Boutros, Paul C, Miller, Naomi, Pintilie, Melania, Fyles, Tony, McCready, David, Wong, Derek, Gerster, Kate, Jurisica, Igor, Penn, Linda Z, Liu, Fei-Fei

“…Global micro-RNA (miR) profiling of human malignancies is increasingly performed, but to date, the majority of such analyses have used frozen tissues. However,…”
Get full text

Hemochromatosis enhances tumor progression via upregulation of intracellular iron in head and neck cancer by Lenarduzzi, Michelle, Hui, Angela B Y, Yue, Shijun, Ito, Emma, Shi, Wei, Williams, Justin, Bruce, Jeff, Sakemura-Nakatsugawa, Noriko, Xu, Wei, Schimmer, Aaron, Liu, Fei-Fei

“…Despite improvements in treatment strategies for head and neck squamous cell carcinoma (HNSCC), outcomes have not significantly improved; highlighting the…”
Get full text

Src and FAK mediate cell-matrix adhesion-dependent activation of met during transformation of breast epithelial cells by Hui, Angela Y., Meens, Jalna A., Schick, Colleen, Organ, Shawna L., Qiao, Hui, Tremblay, Eric A., Schaeffer, Erik, Uniyal, Shashi, Chan, Bosco M.C., Elliott, Bruce E.

“…Cell–matrix adhesion has been shown to promote activation of the hepatocyte growth factor receptor, Met, in a ligand‐independent manner. This process has been…”
Get full text

Comprehensive MicroRNA Profiling for Head and Neck Squamous Cell Carcinomas by HUI, Angela B. Y, LENARDUZZI, Michelle, GULLANE, Pat, CUMMINGS, Bernard, LIU, Fei-Fei, KRUSHEL, Tiffaney, WALDRON, Levi, PINTILIE, Melania, WEI SHI, PEREZ-ORDONEZ, Bayardo, JURISICA, Igor, O'SULLIVAN, Brian, WALDRON, John

“…Purpose: The objective of this study is to investigate the significance of microRNAs (miRNA) in patients with locally advanced head and neck squamous cell…”
Get full text

miR-218 Suppresses Nasopharyngeal Cancer Progression through Downregulation of Survivin and the SLIT2-ROBO1 Pathway by ALAJEZ, Nehad M, LENARDUZZI, Michelle, O'SULLIVAN, Brian, LIU, Fei-Fei, ITO, Emma, HUI, Angela B. Y, WEI SHI, BRUCE, Jeff, SHIJUN YUE, HUANG, Shao H, WEI XU, WALDRON, John

“…Nasopharayngeal carcinoma (NPC) is an Epstein-Barr virus-associated malignancy most common in East Asia and Africa. Here we report frequent downregulation of…”
Get full text

MicroRNA-193b enhances tumor progression via down regulation of neurofibromin 1 by Lenarduzzi, Michelle, Hui, Angela B Y, Alajez, Nehad M, Shi, Wei, Williams, Justin, Yue, Shijun, O'Sullivan, Brian, Liu, Fei-Fei

“…Despite improvements in therapeutic approaches for head and neck squamous cell carcinomas (HNSCC), clinical outcome has remained disappointing, with 5-year…”
Get full text

Standardization of rounds on a general paediatric ward: Implementation of a checklist to improve efficiency, quality of rounds, and family satisfaction by Trahan, Camille, Hui, Angela Y, Binepal, Navneet

“…Abstract Objective The purpose of this study was to develop a standardized rounding tool for use on the general paediatric ward and to determine if its use can…”
Get full text

Potentially Prognostic miRNAs in HPV-Associated Oropharyngeal Carcinoma by HUI, Angela B. Y, LIN, Alice, WALDRON, John, GULLANE, Patrick, IRISH, Jonathan C, CHAN, Kelvin, LI, Fei-Fei, WEI XU, WALDRON, Levi, PEREZ-ORDONEZ, Bayardo, WEINREB, Ilan, WEI SHI, BRUCE, Jeff, SHAO HUI HUANG, O'SULLIVAN, Brian

“…Deregulation of miRNAs is associated with almost all human malignancies. Human papillomavirus (HPV)-associated oropharyngeal carcinoma (OPC) has a…”
Get full text

Detection of oncogene amplifications in medulloblastomas by comparative genomic hybridization and array-based comparative genomic hybridization by TONG, Carol Y. K, HUI, Angela B. Y, YIN, Xiao-Lu, PANG, Jesse C. S, ZHU, Xian-Lun, POON, Wai-Sang, NG, Ho-Keung

“…Few studies have been conducted to investigate the genomic survey of oncogene amplification in medulloblastoma. Low frequency of N-myc, C-myc, and epidermal…”
Get full text

Significance of Plk1 regulation by miR‐100 in human nasopharyngeal cancer by Shi, Wei, Alajez, Nehad M., Bastianutto, Carlo, Hui, Angela B.Y., Mocanu, Joseph D., Ito, Emma, Busson, Pierre, Lo, Kwok‐Wai, Ng, Raymond, Waldron, John, O'Sullivan, Brian, Liu, Fei‐Fei

“…Polo‐like kinase 1 (Plk1) is a critical regulator of many stages of mitosis; increasing evidence indicates that Plk1 overexpression correlates with poor…”
Get full text

Significance of Dysregulated Metadherin and MicroRNA-375 in Head and Neck Cancer by HUI, Angela B. Y, BRUCE, Jeff P, GULLANE, Patrick, LILLIAN SIU, LIU, Fei-Fei, ALAJEZ, Nehad M, WEI SHI, SHIJUN YUE, PEREZ-ORDONEZ, Bayardo, WEI XU, O'SULLIVAN, Brian, WALDRON, John, CUMMINGS, Bernard

“…Despite recent improvements in local control of head and neck cancers (HNC), distant metastasis remains a major cause of death. Hence, further understanding of…”
Get full text

Size Distributions of Maternal and Fetal DNA in Maternal Plasma by Chan, K.C. Allen, Zhang, Jun, Hui, Angela B.Y, Wong, Nathalie, Lau, Tze K, Leung, Tse N, Lo, Kwok-Wai, Huang, Dolly W.S, Lo, Y.M. Dennis

“…The discovery of fetal DNA in maternal plasma has opened up an approach for noninvasive prenatal diagnosis. Despite the rapid expansion in clinical…”
Get full text

Early Circulating Tumor DNA Shedding Kinetics for Prediction of Platinum Sensitivity in Patients With Small Cell Lung Cancer by Murciano-Goroff, Yonina R, Hui, Angela B-Y, Araujo Filho, Jose A, Hamilton, Emily G, Chabon, Jacob J, Moding, Everett J, Bonilla, Rene F, Lebow, Emily S, Gomez, Daniel, Rimner, Andreas, Ginsberg, Michelle S, Offin, Michael, Kundra, Ritika, Allaj, Viola, Norton, Larry, Reis-Filho, Jorge S, Razavi, Pedram, Drilon, Alexander, Jones, David R, Isbell, James M, Lai, W Victoria, Rudin, Charles M, Alizadeh, Ash A, Li, Bob T, Diehn, Maximilian

“…Small cell lung cancer (SCLC) is characterized by rapid progression after platinum resistance. Circulating tumor (ctDNA) dynamics early in treatment may help…”
Get more information

Research capacity and limitations in Canadian paediatric emergency departments: An observational study on biomarker discovery by Mitevska, Elena, Mickiewicz, Beata, Boisvert, Leslie, Bon, Christine, Carciumaru, Redjana, Cook, Ramona, Crawford, Tyrus, Dietz, Joan, Doyle, Melanie, Hui, Angela Y, Stillwell, Karly, Trajtman, Adriana, Beer, Darcy, Bhatt, Maala, Craig, William, Fitzpatrick, Eleanor, Gravel, Jocelyn, Kam, April, Mater, Ahmed, Moffat, Anne, Poonai, Naveen, Sabhaney, Vikram, Thompson, Graham C

“…Abstract Background Paediatric research is essential to acquire effective diagnoses and treatment for children, but it has historically been under-prioritized…”
Get full text

Therapeutic Efficacy of Seliciclib in Combination with Ionizing Radiation for Human Nasopharyngeal Carcinoma by HUI, Angela B. Y, SHIJUN YUE, WEI SHI, ALAJEZ, Nehad M, ITO, Emma, GREEN, Simon R, FRAME, Sheelagh, O'SULLIVAN, Brian, LIU, Fei-Fei

“…Purpose: Seliciclib is a small-molecule cyclin-dependent kinase inhibitor, which has been reported to induce apoptosis and cell cycle arrest in EBV-negative…”
Get full text

CD8+ Tumor-Infiltrating Lymphocyte Abundance Is a Positive Prognostic Indicator in Nasopharyngeal Cancer by Shi, Wei, Fijardo, Mackenzie, Bruce, Jeff P, Su, Jie, Xu, Wei, Bell, Rachel, Bissey, Pierre-Antoine, Hui, Angela B Y, Waldron, John, Pugh, Trevor J, Yip, Kenneth W, Liu, Fei-Fei

“…Tumor-infiltrating lymphocytes (TIL) are immune cell populations found within tumors, critical in the antigen-specific host immune response. In this study, we…”
Get full text

Efficacy of Systemically Administered Mutant Vesicular Stomatitis Virus (VSVΔ51) Combined with Radiation for Nasopharyngeal Carcinoma by ALAJEZ, Nehad M, MOCANU, Joseph D, LO, Kwok-Wai, O'SULLIVAN, Brian, GULLANE, Pat, LIU, Fei-Fei, WEI SHI, CHIA, Marie C, BREITBACH, Caroline J, HUI, Angela B. Y, KNOWLES, Shane, BELL, John C, BUSSON, Pierre, TAKADA, Kenzo

“…Purpose: Nasopharyngeal carcinoma (NPC) is a malignancy of the head and neck region that is associated with EBV latency. Curative treatments for NPC achieve…”
Get full text

4q loss is potentially an important genetic event in MM tumorigenesis: identification of a tumor suppressor gene regulated by promoter methylation at 4q13.3, platelet factor 4 by Cheng, Suk Hang, Ng, Margaret H.L., Lau, Kin Mang, Liu, Herman S.Y., Chan, Joyce C.W., Hui, Angela B.Y., Lo, Kwok Wai, Jiang, Hua, Hou, Jian, Chu, Raymond W., Wong, Wai Shan, Chan, Natalie P.H., Ng, Ho Keung

“…In this study, we have elucidated the chromosomal imbalances in the multistep pathogenesis and delineated several critical tumor suppressor gene (TSG) loci in…”
Get full text