Search Results - "Huh, Jimmy"

Repeated mild closed head injury in neonatal rats results in sustained cognitive deficits associated with chronic microglial activation and neurodegeneration by Raghupathi, Ramesh, Prasad, Rupal, Fox, Douglas, Huh, Jimmy W

“…Abstract Abusive head trauma in infants is a consequence of multiple episodes of abuse and results in axonal injury, brain atrophy, and chronic cognitive…”
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Progesterone treatment following traumatic brain injury in the 11-day-old rat attenuates cognitive deficits and neuronal hyperexcitability in adolescence by Lengel, Dana, Huh, Jimmy W., Barson, Jessica R., Raghupathi, Ramesh

“…Traumatic brain injury (TBI) in children younger than 4 years old results in cognitive and psychosocial deficits in adolescence and adulthood. At 4 weeks…”
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Therapeutic strategies to target acute and long-term sequelae of pediatric traumatic brain injury by Huh, Jimmy W., Raghupathi, Ramesh

“…Pediatric traumatic brain injury (TBI) remains one of the leading causes of morbidity and mortality in children. Experimental and clinical studies demonstrate…”
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Sex and estrous‐phase dependent alterations in depression‐like behavior following mild traumatic brain injury in adolescent rats by Giacometti, Laura L., Huh, Jimmy W., Raghupathi, Ramesh

“…Following mild traumatic brain injury (TBI), high school and collegiate‐aged females tend to report more emotional symptoms than males. Adolescent male and…”
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Minocycline Transiently Reduces Microglia/Macrophage Activation but Exacerbates Cognitive Deficits Following Repetitive Traumatic Brain Injury in the Neonatal Rat by Hanlon, Lauren A., Huh, Jimmy W., Raghupathi, Ramesh

“…Elevated microglial/macrophage-associated biomarkers in the cerebrospinal fluid of infant victims of abusive head trauma (AHT) suggest that these cells play a…”
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Depletion of microglia immediately following traumatic brain injury in the pediatric rat: Implications for cellular and behavioral pathology by Hanlon, Lauren A., Raghupathi, Ramesh, Huh, Jimmy W.

“…The inflammatory response is a significant component of the pathophysiology of pediatric traumatic brain injury. High levels of inflammatory mediators have…”
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Glucocorticoid Receptor Overexpression in the Dorsal Hippocampus Attenuates Spatial Learning and Synaptic Plasticity Deficits after Pediatric Traumatic Brain Injury by Lengel, Dana, Romm, Zoe L, Bostwick, Anna, Huh, Jimmy W, Snyder, Nathaniel W, Smith, George M, Raghupathi, Ramesh

“…Traumatic brain injury (TBI) in children <4 years of age leads to long-term deficits in cognitive and learning abilities that can persist or even worsen as…”
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Association of EEG Background With Diffusion-Weighted Magnetic Resonance Neuroimaging and Short-Term Outcomes After Pediatric Cardiac Arrest by Bach, Ashley M, Kirschen, Matthew P, Fung, France W, Abend, Nicholas S, Ampah, Steve, Mondal, Antara, Huh, Jimmy W, Chen, Shih-Shan L, Yuan, Ian, Graham, Kathryn, Berman, Jeffrey I, Vossough, Arastoo, Topjian, Alexis

“…EEG and MRI features are independently associated with pediatric cardiac arrest (CA) outcomes, but it is unclear whether their combination improves outcome…”
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Invasive Neuromonitoring Modalities in the Pediatric Population by Lang, Shih-Shan, Rahman, Raphia, Kumar, Nankee, Tucker, Alexander, Flanders, Tracy M., Kirschen, Matthew, Huh, Jimmy W.

“…Invasive neuromonitoring has become an important part of pediatric neurocritical care, as neuromonitoring devices provide objective data that can guide patient…”
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Reference Range for Cerebrospinal Fluid Opening Pressure in Children by Avery, Robert A, Shah, Samir S, Licht, Daniel J, Seiden, Jeffrey A, Huh, Jimmy W, Boswinkel, Jan, Ruppe, Michael D, Chew, Amber, Mistry, Rakesh D, Liu, Grant T

“…To the Editor: A reference range for cerebrospinal fluid (CSF) opening pressure in children undergoing diagnostic lumbar puncture has not been established. 1…”
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Ketamine Use in the Intubation of Critically Ill Children with Neurological Indications: A Multicenter Retrospective Analysis by Loi, Mervin V., Lee, Jan Hau, Huh, Jimmy W., Mallory, Palen, Napolitano, Natalie, Shults, Justine, Krawiec, Conrad, Shenoi, Asha, Polikoff, Lee, Al-Subu, Awni, Sanders, Ronald, Toal, Megan, Branca, Aline, Glater-Welt, Lily, Ducharme-Crevier, Laurence, Breuer, Ryan, Parsons, Simon, Harwayne-Gidansky, Ilana, Kelly, Serena, Motomura, Makoto, Gladen, Kelsey, Pinto, Matthew, Giuliano, John, Bysani, Gokul, Berkenbosch, John, Biagas, Katherine, Rehder, Kyle, Kasagi, Mioko, Lee, Anthony, Jung, Philipp, Shetty, Rakshay, Nadkarni, Vinay, Nishisaki, Akira

“…Background Ketamine has traditionally been avoided for tracheal intubations (TIs) in patients with acute neurological conditions. We evaluate its current usage…”
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Intracranial Pressure and Brain Tissue Oxygen Multimodality Neuromonitoring in Gunshot Wounds to the Head in Children by Lang, Shih-Shan, Kumar, Nankee, Zhao, Chao, Rahman, Raphia, Flanders, Tracy M., Heuer, Gregory G., Huh, Jimmy W.

“…Gunshot wounds to the head (GSWH) are a cause of severe penetrating traumatic brain injury (TBI). Although multimodal neuromonitoring has been increasingly…”
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Editorial: Long-term consequences of pediatric traumatic brain injury: Improved understanding to help young patients survive and thrive by Huh, Jimmy, Semple, Bridgette D., Raghupathi, Ramesh

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Prevalence of Isoelectric Electroencephalography Events in Infants and Young Children Undergoing General Anesthesia by Yuan, Ian, Landis, William P, Topjian, Alexis A, Abend, Nicholas S, Lang, Shih-Shan, Huh, Jimmy W, Kirschen, Matthew P, Mensinger, Janell L, Zhang, Bingqing, Kurth, Charles D

“…BACKGROUND:In infants and young children, anesthetic dosing is based on population pharmacokinetics and patient hemodynamics not on patient-specific brain…”
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Stem Cell Therapy for Pediatric Traumatic Brain Injury by Lengel, Dana, Sevilla, Cruz, Romm, Zoe L, Huh, Jimmy W, Raghupathi, Ramesh

“…There has been a growing interest in the potential of stem cell transplantation as therapy for pediatric brain injuries. Studies in pre-clinical models of…”
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Intranasal Administration of Oxytocin Attenuates Social Recognition Deficits and Increases Prefrontal Cortex Inhibitory Postsynaptic Currents following Traumatic Brain Injury by Runyan, Avery, Lengel, Dana, Huh, Jimmy W., Barson, Jessica R., Raghupathi, Ramesh

“…Pediatric traumatic brain injury (TBI) results in heightened risk for social deficits that can emerge during adolescence and adulthood. A moderate TBI in male…”
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Craniectomy for Traumatic Intracranial Hypertension by Huh, Jimmy W, Lang, Shih-Shan, Kilbaugh, Todd J

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Differential Effects of FK506 on Structural and Functional Axonal Deficits After Diffuse Brain Injury in the Immature Rat by DiLeonardi, Ann Mae, Huh, Jimmy W, Raghupathi, Ramesh

“…ABSTRACTDiffuse axonal injury is a major component of traumatic brain injury in children and correlates with long-term cognitive impairment. Traumatic brain…”
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Quantitative electroencephalogram in term neonates under different sleep states by Yuan, Ian, Georgostathi, Georgia, Zhang, Bingqing, Hodges, Ashley, Kurth, C. Dean, Kirschen, Matthew P., Huh, Jimmy W., Topjian, Alexis A., Lang, Shih-shan, Richter, Adam, Abend, Nicholas S., Massey, Shavonne L.

“…Electroencephalogram (EEG) can be used to assess depth of consciousness, but interpreting EEG can be challenging, especially in neonates whose EEG undergo…”
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Midline brain injury in the immature rat induces sustained cognitive deficits, bihemispheric axonal injury and neurodegeneration by Huh, Jimmy W., Widing, Ashley G., Raghupathi, Ramesh

“…Infants and children less than 4 years old suffer chronic cognitive deficits following mild, moderate or severe diffuse traumatic brain injury (TBI). It has…”
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