Search Results - "Huh, Hyun Wook"
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Formulation and statistical analysis of an herbal medicine tablet containing Morus alba leaf extracts
Published in Journal of pharmaceutical investigation (01-11-2019)“…It has reported that Morus alba has properties to treat fever, protect liver damage, improve eyesight, strengthen the joint, facilitate discharge of urine, and…”
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Biomineralized biomimetic organic/inorganic hybrid hydrogels based on hyaluronic acid and poloxamer
Published in Carbohydrate polymers (01-08-2015)“…•Biomineralized organic/inorganic hybrid HA/poloxamer hydrogels were prepared.•We investigated their feasibility as injectable hydrogel system to improve bone…”
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Effect of surfactant on the preparation and characterization of gemcitabine-loaded particles
Published in Journal of pharmaceutical investigation (15-03-2019)“…Gemcitabine is used in the treatment of several solid tumors as one of anticancer nucleoside analogues and is necessary to administer high doses to achieve the…”
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A novel composition of ticagrelor by solid dispersion technique for increasing solubility and intestinal permeability
Published in International journal of pharmaceutics (30-01-2019)“…[Display omitted] The aim of this study is to improve the bioavailability of ticagrelor, BCS class 4 drug, using solid dispersion technique, and to evaluate…”
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Novel self-floating tablet for enhanced oral bioavailability of metformin based on cellulose
Published in International journal of pharmaceutics (05-01-2021)“…[Display omitted] •Metformin loaded HCFT was showed the sustained release profile.•Metformin loaded HCFT was successfully floated in the rabbit stomach over…”
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Systemic Design and Evaluation of Ticagrelor-Loaded Nanostructured Lipid Carriers for Enhancing Bioavailability and Antiplatelet Activity
Published in Pharmaceutics (08-05-2019)“…Ticagrelor (TGL), a P2Y receptor antagonist, is classified as biopharmaceutics classification system (BCS) class IV drug due to its poor solubility and…”
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Bioanalytical Method Development and Validation of Veratraldehyde and Its Metabolite Veratric Acid in Rat Plasma: An Application for a Pharmacokinetic Study
Published in Molecules (Basel, Switzerland) (17-06-2020)“…A simple, sensitive, and rapid UHPLC-MS/MS method was developed for the simultaneous determination of veratraldehyde and its metabolite veratric acid in rat…”
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Characterization of Hepatitis B Surface Antigen Loaded Polylactic Acid-Based Microneedle and Its Dermal Safety Profile
Published in Pharmaceutics (09-06-2020)“…A surge of interest in microneedle (MN) vaccines as a novel vaccination system has emerged. Before the clinical application of MN vaccine, an assessment of…”
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Extended Intake of Mulberry Leaf Extract Delayed Metformin Elimination via Inhibiting the Organic Cation Transporter 2
Published in Pharmaceutics (07-01-2020)“…Diabetes mellitus (DM) has become a major health problem in most countries of the world. DM causes many complications, including hyperglycemia, diabetic…”
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Effect of Ticagrelor, a Cytochrome P450 3A4 Inhibitor, on the Pharmacokinetics of Tadalafil in Rats
Published in Pharmaceutics (20-07-2019)“…Tadalafil is a cytochrome P450 (CYP) 3A4 substrate. Because there are few data on drug-drug interactions, it is advisable to take sufficient consideration when…”
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The Effect of Pharmaceutical Excipients for Applying to Spray-Dried Omega-3 Powder
Published in Applied sciences (20-03-2019)“…Omega-3 fatty acid plays a role in protecting cells in the human body, maintaining the structure of the cell, and helping smooth metabolism. Also, it inhibits…”
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Achyranthis radix Extract-Loaded Eye Drop Formulation Development and Novel Evaluation Method for Dry Eye Treatment
Published in Pharmaceutics (17-02-2020)“…Recently, extract has been studied as a therapeutic agent for dry eye disease that occurs from fine dust. The aim of this study was the development of…”
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Stability evaluation of H3N2 influenza split vaccine in drying process for solidification
Published in Journal of pharmaceutical investigation (2020)“…Purpose Currently, most vaccines have been manufactured in liquid forms that are needed a cold-chain system. However, this system does not guarantee the…”
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Development and evaluation of a film-forming system hybridized with econazole-loaded nanostructured lipid carriers for enhanced antifungal activity against dermatophytes
Published in Acta biomaterialia (01-01-2020)“…Treatment of skin infection by dermatophytes is still limited, and the application of conventional topical formulations (ointments, creams, etc.) cause patient…”
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The Delivery Strategy of Paclitaxel Nanostructured Lipid Carrier Coated with Platelet Membrane
Published in Cancers (11-06-2019)“…Strategies for the development of anticancer drug delivery systems have undergone a dramatic transformation in the last few decades. Lipid-based drug delivery…”
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Strategic approach to developing a self-microemulsifying drug delivery system to enhance antiplatelet activity and bioavailability of ticagrelor
Published in International journal of nanomedicine (01-01-2019)“…Ticagrelor (TCG) is used to inhibit platelet aggregation in patients with acute coronary syndrome, but its poor solubility and low bioavailability limit its in…”
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Statistical approach for solidifying ticagrelor loaded self-microemulsifying drug delivery system with enhanced dissolution and oral bioavailability
Published in Materials Science & Engineering C (01-11-2019)“…The aim of this study was to solidify a ticagrelor loaded self-microemulsifying drug delivery system (TCG-SM) with enhanced dissolution and bioavailability of…”
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