Search Results - "Hugot, JP"
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Management of Pediatric Ulcerative Colitis: Joint ECCO and ESPGHAN Evidence-based Consensus Guidelines
Published in Journal of pediatric gastroenterology and nutrition (01-09-2012)“…BACKGROUND AND AIMS:Pediatric ulcerative colitis (UC) shares many features with adult-onset disease but there are some unique considerations; therefore,…”
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Crohn's disease: the cold chain hypothesis
Published in The Lancet (British edition) (13-12-2003)“…Crohn's disease is the result of an abnormal immune response of the gut mucosa triggered by one or more environmental risk factors in people with predisposing…”
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Inflammatory bowel disease: a complex group of genetic disorders
Published in Baillière's best practice & research. Clinical gastroenterology (01-06-2004)“…Inflammatory bowel disease (IBD) are complex genetic disorders resulting from the complex interplay between several genetic and environmental risk factors. The…”
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PPAR and Crohn’s disease: Another piece of the puzzle?
Published in Gastroenterology (New York, N.Y. 1943) (01-02-2005)Get full text
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Intestinal barrier dysfunction triggered by invasive bacteria
Published in Current opinion in microbiology (01-02-2014)“…Highlights • Bacteria alter the gut permeability by tight junction disassembling and/or actin contraction. • They also favor bacterial translocation through…”
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Phylogeny of Neotropical Monkeys: The Interplay of Morphological, Molecular, and Parasitological Data
Published in Molecular phylogenetics and evolution (01-06-1998)“…Separate independent hypotheses of the phylogenetic relationships among the Platyrrhini monkeys have been produced in a recent past, either based upon…”
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ERNICA guidelines for the management of rectosigmoid Hirschsprung's disease
Published in Orphanet journal of rare diseases (25-06-2020)“…Hirschsprung's disease (HSCR) is a serious congenital bowel disorder with a prevalence of 1/5000. Currently, there is a lack of systematically developed…”
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Inflammatory Bowel Disease in Children and Adolescents: Recommendations for Diagnosis‐The Porto Criteria
Published in Journal of pediatric gastroenterology and nutrition (01-07-2005)“…ABSTRACT Ulcerative colitis and Crohn disease may present before the age of 20 years in 25% to 30% of all patients with inflammatory bowel disease. Reported…”
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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
Published in Nature (London) (31-05-2001)“…Crohn's disease and ulcerative colitis, the two main types of chronic inflammatory bowel disease, are multifactorial conditions of unknown aetiology. A…”
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CARD15 mutations in Blau syndrome
Published in Nature genetics (01-09-2001)“…We have identified three missense mutations in the nucleotide-binding domain (NBD) of CARD15/NOD2 in four French and German families with Blau syndrome. Our…”
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Prevalence of Helminths Infection in Wild Rodents of Northwestern Iran
Published in Archives of Razi Institute (01-02-2024)“…Rodents act as reservoirs, intermediate hosts, or definitive hosts for various zoonotic helminths. Parasitic diseases are among the critical factors affecting…”
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CARD15/NOD2 Mutational Analysis and Genotype-Phenotype Correlation in 612 Patients with Inflammatory Bowel Disease
Published in American journal of human genetics (2002)“…CARD15/NOD2 encodes a protein involved in bacterial recognition by monocytes. Mutations in CARD15 have recently been found in patients with Crohn disease (CD),…”
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Infevers: An evolving mutation database for auto-inflammatory syndromes
Published in Human mutation (01-09-2004)“…The Infevers database (http://fmf.igh.cnrs.fr/infevers/) was established in 2002 to provide investigators with access to a central source of information about…”
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Early development of stricturing or penetrating pattern in Crohn’s disease is influenced by disease location, number of flares, and smoking but not by NOD2/CARD15 genotype
Published in Gut (01-04-2003)“…Background: Crohn’s disease is a heterogeneous entity. Disease behaviour, characterised as stricturing, penetrating, or non-stricturing non-penetrating, is a…”
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Molecular phylogeny of clade III nematodes reveals multiple origins of tissue parasitism
Published in Parasitology (01-09-2007)“…Molecular phylogenetic analyses of 113 taxa representing Ascaridida, Rhigonematida, Spirurida and Oxyurida were used to infer a more comprehensive phylogenetic…”
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Gene-Environment Interaction Modulated by Allelic Heterogeneity in Inflammatory Diseases
Published in Proceedings of the National Academy of Sciences - PNAS (18-03-2003)“…CARD15 is a major susceptibility gene for a frequent multifactorial chronic inflammatory bowel disorder, Crohn disease (CD). By using NF-κB activation assays,…”
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Recurrent Autoimmune Pancreatitis in a 10-Year-Old Boy
Published in Journal of pediatric gastroenterology and nutrition (01-03-2009)Get full text
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Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin
Published in EMBO reports (01-12-2005)“…Tracheal cytotoxin (TCT) was originally described as the minimal effector that was able to reproduce the cytotoxic response of Bordetella pertussis on ciliated…”
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NOD2/CARD15 does not influence response to infliximab in Crohn's disease
Published in Gastroenterology (New York, N.Y. 1943) (01-07-2002)“…Background & Aims: NOD2/CARD15 was recently identified as the first gene underlying Crohn's disease (CD) susceptibility. Monoclonal antibodies to tumor…”
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