Search Results - "Hugo, B"

Refine Results
  1. 1

    Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition by Flyamer, Ilya M., Gassler, Johanna, Imakaev, Maxim, Brandão, Hugo B., Ulianov, Sergey V., Abdennur, Nezar, Razin, Sergey V., Mirny, Leonid A., Tachibana-Konwalski, Kikuë

    Published in Nature (London) (06-04-2017)
    “…Using a single-nucleus Hi-C protocol, the authors find that spatial organization of chromatin during oocyte-to-zygote transition differs between paternal and…”
    Get full text
    Journal Article
  2. 2

    Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging by Gabriele, Michele, Brandão, Hugo B, Grosse-Holz, Simon, Jha, Asmita, Dailey, Gina M, Cattoglio, Claudia, Hsieh, Tsung-Han S, Mirny, Leonid, Zechner, Christoph, Hansen, Anders S

    “…Animal genomes are folded into loops and topologically associating domains (TADs) by CTCF and loop-extruding cohesins, but the live dynamics of loop formation…”
    Get full text
    Journal Article
  3. 3

    A mechanism of cohesin‐dependent loop extrusion organizes zygotic genome architecture by Gassler, Johanna, Brandão, Hugo B, Imakaev, Maxim, Flyamer, Ilya M, Ladstätter, Sabrina, Bickmore, Wendy A, Peters, Jan‐Michael, Mirny, Leonid A, Tachibana, Kikuë

    Published in The EMBO journal (15-12-2017)
    “…Fertilization triggers assembly of higher‐order chromatin structure from a condensed maternal and a naïve paternal genome to generate a totipotent embryo…”
    Get full text
    Journal Article
  4. 4

    Extensive Heterogeneity and Intrinsic Variation in Spatial Genome Organization by Finn, Elizabeth H., Pegoraro, Gianluca, Brandão, Hugo B., Valton, Anne-Laure, Oomen, Marlies E., Dekker, Job, Mirny, Leonid, Misteli, Tom

    Published in Cell (07-03-2019)
    “…Several general principles of global 3D genome organization have recently been established, including non-random positioning of chromosomes and genes in the…”
    Get full text
    Journal Article
  5. 5

    Bacillus subtilis SMC complexes juxtapose chromosome arms as they travel from origin to terminus by Wang, Xindan, Brandão, Hugo B., Le, Tung B. K., Laub, Michael T., Rudner, David Z.

    “…Structural maintenance of chromosomes (SMC) complexes play critical roles in chromosome dynamics in virtually all organisms, but how they function remains…”
    Get full text
    Journal Article
  6. 6

    Tracking and interpreting long-range chromatin interactions with super-resolution live-cell imaging by Brandão, Hugo B., Gabriele, Michele, Hansen, Anders S.

    Published in Current opinion in cell biology (01-06-2021)
    “…Mammalian genomes are organized and regulated through long-range chromatin interactions. Structural loops formed by CCCTC-binding factor (CTCF) and cohesin…”
    Get full text
    Journal Article
  7. 7

    The cell biology of fertilization: Gamete attachment and fusion by Siu, Karen K, Serrão, Vitor Hugo B, Ziyyat, Ahmed, Lee, Jeffrey E

    Published in The Journal of cell biology (04-10-2021)
    “…Fertilization is defined as the union of two gametes. During fertilization, sperm and egg fuse to form a diploid zygote to initiate prenatal development. In…”
    Get full text
    Journal Article
  8. 8

    DNA-loop-extruding SMC complexes can traverse one another in vivo by Brandão, Hugo B., Ren, Zhongqing, Karaboja, Xheni, Mirny, Leonid A., Wang, Xindan

    Published in Nature structural & molecular biology (01-08-2021)
    “…Chromosome organization mediated by structural maintenance of chromosomes (SMC) complexes is vital in many organisms. SMC complexes act as motors that extrude…”
    Get full text
    Journal Article
  9. 9

    Chromosome organization by one-sided and two-sided loop extrusion by Banigan, Edward J, van den Berg, Aafke A, Brandão, Hugo B, Marko, John F, Mirny, Leonid A

    Published in eLife (06-04-2020)
    “…SMC complexes, such as condensin or cohesin, organize chromatin throughout the cell cycle by a process known as loop extrusion. SMC complexes reel in DNA,…”
    Get full text
    Journal Article
  10. 10

    A High-Throughput Image Correlation Method for Rapid Analysis of Fluorophore Photoblinking and Photobleaching Rates by Sehayek, Simon, Gidi, Yasser, Glembockyte, Viktorija, Brandão, Hugo B, François, Paul, Cosa, Gonzalo, Wiseman, Paul W

    Published in ACS nano (22-10-2019)
    “…Super-resolution fluorescence imaging based on localization microscopy requires tuning the photoblinking properties of fluorescent dyes employed. Missing is a…”
    Get full text
    Journal Article
  11. 11

    RNA polymerases as moving barriers to condensin loop extrusion by Brandão, Hugo B., Paul, Payel, vandenBerg, Aafke A., Rudner, David Z., Wang, Xindan, Mirny, Leonid A.

    “…To separate replicated sister chromatids during mitosis, eukaryotes and prokaryotes have structural maintenance of chromosome (SMC) condensin complexes that…”
    Get full text
    Journal Article
  12. 12

    Transcription shapes 3D chromatin organization by interacting with loop extrusion by Banigan, Edward J, Tang, Wen, van den Berg, Aafke A, Stocsits, Roman R, Wutz, Gordana, Brandão, Hugo B, Busslinger, Georg A, Peters, Jan-Michael, Mirny, Leonid A

    “…Cohesin folds mammalian interphase chromosomes by extruding the chromatin fiber into numerous loops. "Loop extrusion" can be impeded by chromatin-bound…”
    Get full text
    Journal Article
  13. 13

    DNA double-strand break end synapsis by DNA loop extrusion by Yang, Jin H., Brandão, Hugo B., Hansen, Anders S.

    Published in Nature communications (06-04-2023)
    “…DNA double-strand breaks (DSBs) occur every cell cycle and must be efficiently repaired. Non-homologous end joining (NHEJ) is the dominant pathway for DSB…”
    Get full text
    Journal Article
  14. 14
  15. 15

    Larval Export from Marine Reserves and the Recruitment Benefit for Fish and Fisheries by Harrison, Hugo B., Williamson, David H., Evans, Richard D., Almany, Glenn R., Thorrold, Simon R., Russ, Garry R., Feldheim, Kevin A., van Herwerden, Lynne, Planes, Serge, Srinivasan, Maya, Berumen, Michael L., Jones, Geoffrey P.

    Published in Current biology (05-06-2012)
    “…Marine reserves, areas closed to all forms of fishing, continue to be advocated and implemented to supplement fisheries and conserve populations [1–4]…”
    Get full text
    Journal Article
  16. 16

    Genome-wide identification, characterization and expression profile analysis of expansins gene family in sugarcane (Saccharum spp.) by Santiago, Thaís R, Pereira, Valquiria M, de Souza, Wagner R, Steindorff, Andrei S, Cunha, Bárbara A D B, Gaspar, Marília, Fávaro, Léia C L, Formighieri, Eduardo F, Kobayashi, Adilson K, C Molinari, Hugo B

    Published in PloS one (11-01-2018)
    “…Expansins refer to a family of closely related non-enzymatic proteins found in the plant cell wall that are involved in the cell wall loosening. In addition,…”
    Get full text
    Journal Article
  17. 17

    XerD unloads bacterial SMC complexes at the replication terminus by Karaboja, Xheni, Ren, Zhongqing, Brandão, Hugo B., Paul, Payel, Rudner, David Z., Wang, Xindan

    Published in Molecular cell (18-02-2021)
    “…Bacillus subtilis structural maintenance of chromosomes (SMC) complexes are topologically loaded at centromeric sites adjacent to the replication origin by the…”
    Get full text
    Journal Article
  18. 18
  19. 19

    MCM complexes are barriers that restrict cohesin-mediated loop extrusion by Dequeker, Bart J. H., Scherr, Matthias J., Brandão, Hugo B., Gassler, Johanna, Powell, Sean, Gaspar, Imre, Flyamer, Ilya M., Lalic, Aleksandar, Tang, Wen, Stocsits, Roman, Davidson, Iain F., Peters, Jan-Michael, Duderstadt, Karl E., Mirny, Leonid A., Tachibana, Kikuë

    Published in Nature (London) (02-06-2022)
    “…Eukaryotic genomes are compacted into loops and topologically associating domains (TADs) 1 – 3 , which contribute to transcription, recombination and genomic…”
    Get full text
    Journal Article
  20. 20

    Organization and replicon interactions within the highly segmented genome of Borrelia burgdorferi by Ren, Zhongqing, Takacs, Constantin N, Brandão, Hugo B, Jacobs-Wagner, Christine, Wang, Xindan

    Published in PLoS genetics (26-07-2023)
    “…Borrelia burgdorferi, a causative agent of Lyme disease, contains the most segmented bacterial genome known to date, with one linear chromosome and over twenty…”
    Get full text
    Journal Article