Search Results - "Hughes, Maureen"

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    T cell receptor CDR3 loop length repertoire is determined primarily by features of the V(D)J recombination reaction by Hughes, Maureen M., Yassai, Maryam, Sedy, John R., Wehrly, Tara D., Huang, Ching‐Yu, Kanagawa, Osami, Gorski, Jack, Sleckman, Barry P.

    Published in European journal of immunology (01-06-2003)
    “…The third complementarity‐determining region (CDR) of the TCR α and β chains forms loops that engage amino acid residues of peptides complexed with MHC. This…”
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    Journal Article
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    Mechanisms That Direct Ordered Assembly of T Cell Receptor β Locus V, D, and J Gene Segments by Sleckman, Barry P., Bassing, Craig H., Hughes, Maureen M., Okada, Ami, D'Auteuil, Margaux, Wehrly, Tara D., Woodman, Barbara B., Davidson, Laurie, Chen, Jianzhu, Alt, Frederick W.

    “…T cell receptor (TCR) β variable region genes are assembled in progenitor T cells from germ-line Vβ , Dβ , and Jβ segments via an ordered two-step process in…”
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    Journal Article
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    Regulation of T-cell receptor β-chain gene assembly by recombination signals: the beyond 12/23 restriction by Tillman, Robert E., Wooley, Andrea L., Hughes, Maureen M., Khor, Bernard, Sleckman, Barry P.

    Published in Immunological reviews (01-08-2004)
    “…Assembly of antigen receptor genes is regulated in several important contexts during lymphocyte development. This regulation occurs through modulation of gene…”
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    Journal Article
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    The B12/23 Restriction Is Critically Dependent on Recombination Signal Nonamer and Spacer Sequences by Hughes, Maureen M, Tillman, Robert E, Wehrly, Tara D, White, J. Michael, Sleckman, Barry P

    Published in The Journal of immunology (1950) (15-12-2003)
    “…Ag receptor variable region gene assembly is initiated through the formation of a synaptic complex which minimally includes the recombination-activating gene…”
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    Journal Article
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    Restrictions limiting the generation of DNA double strand breaks during chromosomal V(D)J recombination by Tillman, Robert E, Wooley, Andrea L, Hughes, Maureen M, Wehrly, Tara D, Swat, Wojciech, Sleckman, Barry P

    Published in The Journal of experimental medicine (04-02-2002)
    “…Antigen receptor loci are composed of numerous variable (V), diversity (D), and joining (J) gene segments, each flanked by recombination signal sequences…”
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    Journal Article
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    Speaking and listening in the primary curriculum: some themes and their impact by Westgate, David, Hughes, Maureen

    Published in Education 3-13 (03-07-2016)
    “…In a previous phase of a project based in a group of UK primary schools, speaking and listening was found to be an effective focus for improved learning across…”
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    Journal Article
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    Speaking and listening across the primary curriculum: an entry to improved learning and a focus for CPD by Westgate, David, Hughes, Maureen

    Published in Education 3-13 (03-09-2015)
    “…This paper reports on the initial stage of an exploratory project based in six primary schools in Newcastle upon Tyne (UK) - and on plans for its extension…”
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    Journal Article
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    Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule by Sleckman, Barry P, Bassing, Craig H, Alt, Frederick W, Hughes, Maureen M, D'Auteuil, Margaux, Wehrly, Tara D, Woodman, Barbara B, Gärtner, Frank, White, J. Michael, Davidson, Laurie

    Published in Nature (London) (01-06-2000)
    “…The genes encoding the variable regions of lymphocyte antigen receptors are assembled from variable (V), diversity (D) and joining (J) gene segments. V(D)J…”
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    Journal Article
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    Tipping the tower of PISA: Cross-national learning as a strategy to inform leaders about diverse students and achievement in the global neighborhood by Hughes, Maureen O'Reilly

    Published 01-01-2013
    “…Despite the inherent obstacles posed by increasingly diverse student populations, school leaders worldwide are under mounting pressure to raise student…”
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    Dissertation
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    Identifying 'Quality' in Classroom Talk: An Enduring Research Task by Westgate, David, Hughes, Maureen

    Published in Language and education (1997)
    “…After 20 or more years of classroom research using recorded talk-data, many of the substantive as well as the methodological issues addressed by pioneers in…”
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    Journal Article
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    Ion-Exchange Chromatography Followed by ESI-MS for Quantitative Analysis of Sugar Monophosphates from Glucose Catabolism by Walters, James J., Grayson, Michael A., Gross, Michael L., Hughes, Maureen, Shearer, Georgia, Kohl, Daniel H., Bashkin, James

    “…The aim of this work is to establish a quantitative method to determine the ratio of [U- 13C] labeled to unlabeled hexose monophosphates isolated from yeast…”
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    Journal Article
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    Possible Enabling Strategies in Teacher-led Talk with Young Pupils by Hughes, Maureen, Westgate, David

    Published in Language and education (1998)
    “…It has been established that some teachers show themselves to be 'better' talk-partners for young pupils than others, in that they co-construct contexts in…”
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    Journal Article
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    Functional analysis of requirements for the targeting of V beta to D beta rearrangement in the TCR beta locus by Hughes, Maureen Marie

    “…In the TCR Beta locus, variable (V), diversity (D), and joining (J) gene segments assemble by a process known as V(D)J recombination. Assembly in the TCR Beta…”
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    Dissertation
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    Tipping the tower of PISA: Cross-national learning as a strategy to inform leaders about diverse students and achievement in the global neighborhood by Hughes, Maureen O'Reilly

    “…Despite the inherent obstacles posed by increasingly diverse student populations, school leaders worldwide are under mounting pressure to raise student…”
    Get full text
    Dissertation
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    Functional analysis of requirements for the targeting of V beta to D beta rearrangement in the TCR beta locus by Hughes, Maureen Marie

    Published 01-01-2003
    “…In the TCR Beta locus, variable (V), diversity (D), and joining (J) gene segments assemble by a process known as V(D)J recombination. Assembly in the TCR Beta…”
    Get full text
    Dissertation
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