Search Results - "Hughes, Martin N"

Chemistry of nitric oxide and related species by Hughes, Martin N

“…Nitric oxide (NO) has essential roles in a remarkable number of diverse biological processes. The reactivity of NO depends upon its physical properties, such…”
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New functions for the ancient globin family: bacterial responses to nitric oxide and nitrosative stress by Poole, Robert K., Hughes, Martin N.

“…Globin‐like oxygen‐binding proteins occur in bacteria, yeasts and other fungi, and protozoa. The simplest contain protohaem as sole prosthetic group, but show…”
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Transcriptional Responses of Escherichia coli to S-Nitrosoglutathione under Defined Chemostat Conditions Reveal Major Changes in Methionine Biosynthesis by Flatley, Janet, Barrett, Jason, Pullan, Steven T., Hughes, Martin N., Green, Jeffrey, Poole, Robert K.

“…Nitric oxide and nitrosating agents exert powerful antimicrobial effects and are central to host defense and signal transduction. Nitric oxide and…”
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Making and working with hydrogen sulfide: The chemistry and generation of hydrogen sulfide in vitro and its measurement in vivo: a review by Hughes, Martin N, Centelles, Miguel N, Moore, Kevin P

“…Hydrogen sulfide is rapidly emerging as an important vasoactive mediator formed in health and disease. Its biological action is centered on its reactivity with…”
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Nitrite and nitrosyl compounds in food preservation by Cammack, Richard, Joannou, C.L, Cui, Xiao-Yuan, Torres Martinez, Claudia, Maraj, Shaun R, Hughes, Martin N

“…Nitrite is consumed in the diet, through vegetables and drinking water. It is also added to meat products as a preservative. The potential risks of this…”
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Kinetics of the reactions of nitrogen dioxide with glutathione, cysteine, and uric acid at physiological pH by Ford, Eleonora, Hughes, Martin N., Wardman, Peter

“…Nitrogen dioxide (NO 2 •) is a key biological oxidant. It can be derived from peroxynitrite via the interaction of nitric oxide with superoxide, from nitrite…”
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Relationships between nitric oxide, nitroxyl ion, nitrosonium cation and peroxynitrite by Hughes, Martin N.

“…This review is concerned mainly with the three redox-related, but chemically distinct, species NO −, NO ⋅ and NO +, with greatest emphasis being placed on the…”
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Interaction of bilirubin and biliverdin with reactive nitrogen species by Kaur, Harparkash, Hughes, Martin N., Green, Colin J., Naughton, Patrick, Foresti, Roberta, Motterlini, Roberto

“…Bilirubin (BR) and biliverdin (BV), two metabolites produced during haem degradation by haem oxygenase, possess strong antioxidant activities toward peroxyl…”
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NO sensing by FNR: regulation of the Escherichia coli NO-detoxifying flavohaemoglobin, Hmp by Cruz-Ramos, Hugo, Crack, Jason, Wu, Guanghui, Hughes, Martin N., Scott, Colin, Thomson, Andrew J., Green, Jeffrey, Poole, Robert K.

“…Nitric oxide (NO) is a signalling and defence molecule of major importance in biology. The flavohaemoglobin Hmp of Escherichia coli is involved in protective…”
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Escherichia coli flavohaemoglobin (Hmp) reduces cytochrome c and Fe(III)-hydroxamate K by electron transfer from NADH via FAD: sensitivity of oxidoreductase activity to haem-bound dioxygen by Poole, Robert K, Rogers, Nicola J, D'mello, Rita A. M, Hughes, Martin N, Orii, Yutaka

“…1 Division of Life Sciences, King's College London, Campden Hill Road, London W8 7AH, UK 2 Chemistry Department, King's College London, Strand, London WC2R…”
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Anoxic function for the Escherichia coli flavohaemoglobin (Hmp): reversible binding of nitric oxide and reduction to nitrous oxide by Kim, Sung Oog, Orii, Yutaka, Lloyd, David, Hughes, Martin N., Poole, Robert K.

“…The flavohaemoglobin Hmp of Escherichia coli is inducible by nitric oxide (NO) and provides protection both aerobically and anaerobically from inhibition of…”
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Characterization of the bactericidal effects of sodium nitroprusside and other pentacyanonitrosyl complexes on the food spoilage bacterium Clostridium sporogenes by Joannou, C.L. (King's College London, London, UK.), Cui, X.Y, Rogers, N, Vielotte, N, Martinez, C.L.T, Vugman, N.V, Hughes, M.N, Cammack, R

“…The potent bactericidal activity of sodium nitroprusside (SNP; Na2[Fe(CN)5(NO)]) towards Clostridium sporogenes has been investigated. SNP inhibited cell…”
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Synthesis, chemistry, and applications of nitroxyl ion releasers sodium trioxodinitrate or Angeli's salt and Piloty's acid by Hughes, M N, Cammack, R

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The preparation and purification of NO gas and the use of NO releasers: the application of NO donors and other agents of nitrosative stress in biological systems by Aga, Rubina G, Hughes, Martin N

“…Cylinders and lecture bottles are often the source of nitric oxide (NO) in studies of the biological chemistry of this remarkable molecule. The NO from both…”
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The Flavohemoglobin of Escherichia coli Confers Resistance to a Nitrosating Agent, a “Nitric Oxide Releaser,” and Paraquat and Is Essential for Transcriptional Responses to Oxidative Stress by Membrillo-Hernández, Jorge, Coopamah, Malini D., Anjum, Muna F., Stevanin, Tania M., Kelly, Andrew, Hughes, Martin N., Poole, Robert K.

“…Escherichia coli possesses a flavohemoglobin (Hmp), product of hmp, the first microbial globin gene to be sequenced and characterized at the molecular level…”
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Inhibitory effects of sulfamic acid on three thiosulfate-oxidizing chemolithotrophs by Lusty, James R., Hughes, Martin N., Kelly, Donovan P.

“…Abstract Sulfamate is an analogue of thiosulfate, and the sodium and potassium salts of sulfamic acid inhibited the chemolithoautotrophic growth on thiosulfate…”
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Evidence for the transport of zinc(II) ions via the Pit inorganic phosphate transport system in Escherichia coli by Beard, Steven J., Hashim, Rohani, Wu, Guanghui, Binet, Marie R.B., Hughes, Martin N., Poole, Robert K.

“…Abstract A locus involved in zinc(II) uptake in Escherichia coli K-12 was identified through the generation of a zinc(II)-resistant mutant by transposon…”
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Copper biosorption by Pseudomonas cepacia and other strains by SAVVAIDIS, Ioannis, HUGHES, Martin N, POOLE, Robert K

“…Biosorption of copper by Pseudomonas cepacia was found to be dependent on added copper concentration. Copper uptake by the cells was rapid over the range of…”
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The reaction of superoxide radicals with S-nitrosoglutathione and the products of its reductive heterolysis by Ford, Eleonora, Hughes, Martin N, Wardman, Peter

“…Generation of superoxide radicals (0.01-0.1 microm s(-1)) by radiolysis of aqueous solutions containing S-nitrosoglutathione (45-160 microm, pH 3.8-7.3)…”
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Nitric oxide releases intracellular zinc from prokaryotic metallothionein in Escherichia coli by Binet, Marie R.B, Cruz-Ramos, Hugo, Laver, Jay, Hughes, Martin N, Poole, Robert K

“…Nitric oxide (NO) has a broad spectrum of signalling and regulatory functions and multiple molecular targets. Recently, the intrabacterial toxicity of NO and…”
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