Search Results - "Hughes, Elizabeth R."

Precision editing of the gut microbiota ameliorates colitis by Zhu, Wenhan, Winter, Maria G., Byndloss, Mariana X., Spiga, Luisella, Duerkop, Breck A., Hughes, Elizabeth R., Büttner, Lisa, de Lima Romão, Everton, Behrendt, Cassie L., Lopez, Christopher A., Sifuentes-Dominguez, Luis, Huff-Hardy, Kayci, Wilson, R. Paul, Gillis, Caroline C., Tükel, Çagla, Koh, Andrew Y., Burstein, Ezra, Hooper, Lora V., Bäumler, Andreas J., Winter, Sebastian E.

“…Tungstate inhibits molybdenum-cofactor-dependent microbial respiratory pathways and shows potential as a selective treatment for microbial imbalances that…”
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Microbial Respiration and Formate Oxidation as Metabolic Signatures of Inflammation-Associated Dysbiosis by Hughes, Elizabeth R., Winter, Maria G., Duerkop, Breck A., Spiga, Luisella, Furtado de Carvalho, Tatiane, Zhu, Wenhan, Gillis, Caroline C., Büttner, Lisa, Smoot, Madeline P., Behrendt, Cassie L., Cherry, Sara, Santos, Renato L., Hooper, Lora V., Winter, Sebastian E.

“…Intestinal inflammation is frequently associated with an alteration of the gut microbiota, termed dysbiosis, which is characterized by a reduced abundance…”
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Editing of the gut microbiota reduces carcinogenesis in mouse models of colitis-associated colorectal cancer by Zhu, Wenhan, Miyata, Naoteru, Winter, Maria G, Arenales, Alexandre, Hughes, Elizabeth R, Spiga, Luisella, Kim, Jiwoong, Sifuentes-Dominguez, Luis, Starokadomskyy, Petro, Gopal, Purva, Byndloss, Mariana X, Santos, Renato L, Burstein, Ezra, Winter, Sebastian E

“…Chronic inflammation and gut microbiota dysbiosis, in particular the bloom of genotoxin-producing strains, are risk factors for the development of colorectal…”
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Dysbiosis-Associated Change in Host Metabolism Generates Lactate to Support Salmonella Growth by Gillis, Caroline C., Hughes, Elizabeth R., Spiga, Luisella, Winter, Maria G., Zhu, Wenhan, Furtado de Carvalho, Tatiane, Chanin, Rachael B., Behrendt, Cassie L., Hooper, Lora V., Santos, Renato L., Winter, Sebastian E.

“…During Salmonella-induced gastroenteritis, mucosal inflammation creates a niche that favors the expansion of the pathogen population over the microbiota. Here,…”
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An Oxidative Central Metabolism Enables Salmonella to Utilize Microbiota-Derived Succinate by Spiga, Luisella, Winter, Maria G., Furtado de Carvalho, Tatiane, Zhu, Wenhan, Hughes, Elizabeth R., Gillis, Caroline C., Behrendt, Cassie L., Kim, Jiwoong, Chessa, Daniela, Andrews-Polymenis, Helene L., Beiting, Daniel P., Santos, Renato L., Hooper, Lora V., Winter, Sebastian E.

“…The mucosal inflammatory response induced by Salmonella serovar Typhimurium creates a favorable niche for this gut pathogen. Conventional wisdom holds that S…”
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Epithelial-Derived Reactive Oxygen Species Enable AppBCX-Mediated Aerobic Respiration of Escherichia coli during Intestinal Inflammation by Chanin, Rachael B., Winter, Maria G., Spiga, Luisella, Hughes, Elizabeth R., Zhu, Wenhan, Taylor, Savannah J., Arenales, Alexandre, Gillis, Caroline C., Büttner, Lisa, Jimenez, Angel G., Smoot, Madeline P., Santos, Renato L., Winter, Sebastian E.

“…The intestinal epithelium separates host tissue and gut-associated microbial communities. During inflammation, the host releases reactive oxygen and nitrogen…”
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Enterococcus faecalis: E. coli’s Siderophore-Inducing Sidekick by Hughes, Elizabeth R., Winter, Sebastian E.

“…Many infectious diseases involve polymicrobial infections, which are characterized by synergistic interactions between different microorganisms colonizing a…”
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Formate oxidation in the intestinal mucus layer enhances fitness of Salmonella enterica serovar Typhimurium by Winter, Maria G, Hughes, Elizabeth R, Muramatsu, Matthew K, Jimenez, Angel G, Chanin, Rachael B, Spiga, Luisella, Gillis, Caroline C, McClelland, Michael, Andrews-Polymenis, Helene, Winter, Sebastian E

“…serovar Typhimurium induces intestinal inflammation to create a niche that fosters the outgrowth of the pathogen over the gut microbiota. Under inflammatory…”
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Reshaping of bacterial molecular hydrogen metabolism contributes to the outgrowth of commensal E. coli during gut inflammation by Hughes, Elizabeth R, Winter, Maria G, Alves da Silva, Laice, Muramatsu, Matthew K, Jimenez, Angel G, Gillis, Caroline C, Spiga, Luisella, Chanin, Rachael B, Santos, Renato L, Zhu, Wenhan, Winter, Sebastian E

“…The composition of gut-associated microbial communities changes during intestinal inflammation, including an expansion of Enterobacteriaceae populations. The…”
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Dysbiosis-Associated Change in Host Metabolism Generates Lactate to Support Salmonella Growth by Gillis, Caroline C., Hughes, Elizabeth R., Spiga, Luisella, Winter, Maria G., Zhu, Wenhan, Furtado de Carvalho, Tatiane, Chanin, Rachael B., Behrendt, Cassie L., Hooper, Lora V., Santos, Renato L., Winter, Sebastian E.

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Xenosiderophore Utilization Promotes Bacteroides thetaiotaomicron Resilience during Colitis by Zhu, Wenhan, Winter, Maria G., Spiga, Luisella, Hughes, Elizabeth R., Chanin, Rachael, Mulgaonkar, Aditi, Pennington, Jenelle, Maas, Michelle, Behrendt, Cassie L., Kim, Jiwoong, Sun, Xiankai, Beiting, Daniel P., Hooper, Lora V., Winter, Sebastian E.

“…During short-lived perturbations, such as inflammation, the gut microbiota exhibits resilience and reverts to its original configuration. Although microbial…”
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Mechanism of 2'-fucosyllactose degradation by human-associated Akkermansia by Padilla, Loren, Fricker, Ashwana D, Luna, Estefani, Choudhury, Biswa, Hughes, Elizabeth R, Panzetta, Maria E, Valdivia, Raphael H, Flores, Gilberto E

“…Among the first microorganisms to colonize the human gut of breastfed infants are bacteria capable of fermenting human milk oligosaccharides (HMOs). One of the…”
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Enterococcus faecalis : E. coli ’s Siderophore-Inducing Sidekick by Hughes, Elizabeth R., Winter, Sebastian E.

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