Search Results - "Hughes, Barry D."

Distinguishing cell shoving mechanisms by Nan, Pingyu, Walsh, Darragh M, Landman, Kerry A, Hughes, Barry D

“…Motivated by in vitro time-lapse images of ovarian cancer spheroids inducing mesothelial cell clearance, the traditional agent-based model of cell migration,…”
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A computational model for collective cellular motion in three dimensions: general framework and case study for cell pair dynamics by Frascoli, Federico, Hughes, Barry D, Zaman, Muhammad H, Landman, Kerry A

“…Cell migration in healthy and diseased systems is a combination of single and collective cell motion. While single cell motion has received considerable…”
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Is cell migration or proliferation dominant in the formation of linear arrays of oligodendrocytes? by Walsh, Darragh M., Röth, Philipp T., Holmes, William R., Landman, Kerry A., Merson, Tobias D., Hughes, Barry D.

“…Oligodendrocytes are the myelin-producing cells of the central nervous system that are responsible for electrically insulating axons to speed the propagation…”
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Evidence for Cooperative Selection of Axons for Myelination by Adjacent Oligodendrocytes in the Optic Nerve by Walsh, Darragh M, Merson, Tobias D, Landman, Kerry A, Hughes, Barry D

“…The cellular mechanisms that regulate the topographic arrangement of myelin internodes along axons remain largely uncharacterized. Recent clonal analysis of…”
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An in silico agent-based model demonstrates Reelin function in directing lamination of neurons during cortical development by Caffrey, James R, Hughes, Barry D, Britto, Joanne M, Landman, Kerry A

“…The characteristic six-layered appearance of the neocortex arises from the correct positioning of pyramidal neurons during development and alterations in this…”
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Looking inside an invasion wave of cells using continuum models: Proliferation is the key by Simpson, Matthew J., Landman, Kerry A., Hughes, Barry D., F. Newgreen, Donald

“…Recently, a suite of cell migration assays were conducted to investigate the migration of neural crest (NC) cells along the gut during the development of the…”
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Infection-acquired versus vaccine-acquired immunity in an SIRWS model by Leung, Tiffany, Campbell, Patricia T., Hughes, Barry D., Frascoli, Federico, McCaw, James M.

“…In some disease systems, the process of waning immunity can be subtle, involving a complex relationship between the duration of immunity—acquired either…”
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Watching the Internal Clock of Cells while They Move and Divide by Hughes, Barry D.

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Interatomic force laws that evade dynamic measurement by Sader, John E., Hughes, Barry D., Huber, Ferdinand, Giessibl, Franz J.

“…Measurement of the force between two atoms is performed routinely with the atomic force microscope. The shape of this interatomic force law is now found to…”
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Dissecting the dynamics of epigenetic changes in phenotype-structured populations exposed to fluctuating environments by Lorenzi, Tommaso, Chisholm, Rebecca H., Desvillettes, Laurent, Hughes, Barry D.

“…An enduring puzzle in evolutionary biology is to understand how individuals and populations adapt to fluctuating environments. Here we present an…”
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3D hybrid modelling of vascular network formation by Perfahl, Holger, Hughes, Barry D., Alarcón, Tomás, Maini, Philip K., Lloyd, Mark C., Reuss, Matthias, Byrne, Helen M.

“…We develop an off-lattice, agent-based model to describe vasculogenesis, the de novo formation of blood vessels from endothelial progenitor cells during…”
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Evolutionary dynamics of phenotype-structured populations: from individual-level mechanisms to population-level consequences by Chisholm, Rebecca H., Lorenzi, Tommaso, Desvillettes, Laurent, Hughes, Barry D.

“…Epigenetic mechanisms are increasingly recognised as integral to the adaptation of species that face environmental changes. In particular, empirical work has…”
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Solutions of a non‐local aggregation equation: Universal bounds, concavity changes, and efficient numerical solutions by Fellner, Klemens, Hughes, Barry D.

“…We consider a one‐dimensional aggregation equation for a non‐negative density ρ(x,t) associated with a quartic potential W(x)=βx2+δx4 ( δ>0, β∈R). We show that…”
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Building macroscale models from microscale probabilistic models: a general probabilistic approach for nonlinear diffusion and multispecies phenomena by Penington, Catherine J, Hughes, Barry D, Landman, Kerry A

“…A discrete agent-based model on a periodic lattice of arbitrary dimension is considered. Agents move to nearest-neighbor sites by a motility mechanism…”
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Cell invasion with proliferation mechanisms motivated by time-lapse data by Simpson, Matthew J., Landman, Kerry A., Hughes, Barry D.

“…Cell invasion involves a population of cells which are motile and proliferative. Traditional discrete models of proliferation involve agents depositing…”
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Why we do not expect dispersal probability density functions based on a single mechanism to fit real seed shadows by Cousens, Roger D., Hughes, Barry D., Mesgaran, Mohsen B.

“…1. Bullock et al. (Journal of Ecology 105:6-19, 2017) have suggested that the theory behind the Wald Analytical Long Distance (WALD) model for wind dispersal…”
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Periodic solutions in an SIRWS model with immune boosting and cross-immunity by Leung, Tiffany, Hughes, Barry D., Frascoli, Federico, McCaw, James M.

“…Incidence of whooping cough, an infection caused by Bordetella pertussis and Bordetella parapertussis, has been on the rise since the 1980s in many countries…”
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Publisher Correction: Interatomic force laws that evade dynamic measurement by Sader, John E., Hughes, Barry D., Huber, Ferdinand, Giessibl, Franz J.

“…In the version of this Comment originally published, equation (4) was incorrect; see the correction notice for details. This has now been corrected in the…”
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What is the optimal distribution of myelin along a single axon? by Walsh, Darragh M., Landman, Kerry A., Hughes, Barry D.

“…•Ion channel distribution determines the optimal pattern of partial myelination.•Short node-internode pairs yield fastest conduction if channel number is…”
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A dynamical model of tumour immunotherapy by Frascoli, Federico, Kim, Peter S., Hughes, Barry D., Landman, Kerry A.

“…•A new ODE model of tumour-immune dynamics is analysed.•Solutions show oscillations between cancer volume and immune cells.•Tumour shape has consequences for…”
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