Search Results - "Hughes, Anastasia"

Murine bone-derived mesenchymal stem cells undergo molecular changes after a single passage in culture by Hughes, Anastasia M., Kuek, Vincent, Oommen, Joyce, Kotecha, Rishi S., Cheung, Laurence C.

“…The rarity of the mesenchymal stem cell (MSC) population poses a significant challenge for MSC research. Therefore, these cells are often expanded in vitro,…”
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Therapeutic Targeting of the Leukaemia Microenvironment by Kuek, Vincent, Hughes, Anastasia M, Kotecha, Rishi S, Cheung, Laurence C

“…In recent decades, the conduct of uniform prospective clinical trials has led to improved remission rates and survival for patients with acute myeloid…”
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The Bone Marrow Microenvironment in B-Cell Development and Malignancy by Hughes, Anastasia M, Kuek, Vincent, Kotecha, Rishi S, Cheung, Laurence C

“…B lymphopoiesis is characterized by progressive loss of multipotent potential in hematopoietic stem cells, followed by commitment to differentiate into B…”
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New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment by Cheung, Laurence C., Tickner, Jennifer, Hughes, Anastasia M., Skut, Patrycja, Howlett, Meegan, Foley, Bree, Oommen, Joyce, Wells, Julia E., He, Bo, Singh, Sajla, Chua, Grace-Alyssa, Ford, Jette, Mullighan, Charles G., Kotecha, Rishi S., Kees, Ursula R.

“…The microenvironments of leukemia and cancer are critical for multiple stages of malignancies, and they are an attractive therapeutic target. While skeletal…”
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The bone marrow microenvironment of pre-B acute lymphoblastic leukemia at single-cell resolution by Anderson, Denise, Skut, Patrycja, Hughes, Anastasia M., Ferrari, Emanuela, Tickner, Jennifer, Xu, Jiake, Mullin, Benjamin H., Tang, Dave, Malinge, Sébastien, Kees, Ursula R., Kotecha, Rishi S., Lassmann, Timo, Cheung, Laurence C.

“…The bone marrow microenvironment (BMM) plays a key role in leukemia progression, but its molecular complexity in pre-B cell acute lymphoblastic leukemia…”
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Characterization of mesenchymal stem cells in pre-B acute lymphoblastic leukemia by Hughes, Anastasia M, Kuek, Vincent, Oommen, Joyce, Chua, Grace-Alyssa, van Loenhout, Maria, Malinge, Sebastien, Kotecha, Rishi S, Cheung, Laurence C

“…Components of the bone marrow microenvironment (BMM) have been shown to mediate the way in which leukemia develops, progresses and responds to treatment…”
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Preclinical efficacy of azacitidine and venetoclax for infant KMT2A-rearranged acute lymphoblastic leukemia reveals a new therapeutic strategy by Cheung, Laurence C., Aya-Bonilla, Carlos, Cruickshank, Mark N., Chiu, Sung K., Kuek, Vincent, Anderson, Denise, Chua, Grace-Alyssa, Singh, Sajla, Oommen, Joyce, Ferrari, Emanuela, Hughes, Anastasia M., Ford, Jette, Kunold, Elena, Hesselman, Maria C., Post, Frederik, Faulk, Kelly E., Breese, Erin H., Guest, Erin M., Brown, Patrick A., Loh, Mignon L., Lock, Richard B., Kees, Ursula R., Jafari, Rozbeh, Malinge, Sébastien, Kotecha, Rishi S.

“…Infants with KMT2A -rearranged B-cell acute lymphoblastic leukemia (ALL) have a dismal prognosis. Survival outcomes have remained static in recent decades…”
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Romidepsin enhances the efficacy of cytarabine in vivo , revealing histone deacetylase inhibition as a promising therapeutic strategy for KMT2A -rearranged infant acute lymphoblastic leukemia by Cheung, Laurence C, Cruickshank, Mark N, Hughes, Anastasia M, Singh, Sajla, Chua, Grace-Alyssa, Ford, Jette, Ferrari, Emanuela, Oommen, Joyce, Malinge, Sébastien, Lock, Richard B, Kees, Ursula R, Kotecha, Rishi S

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Preclinical Evaluation of Carfilzomib for Infant KMT2A -Rearranged Acute Lymphoblastic Leukemia by Cheung, Laurence C, de Kraa, Rebecca, Oommen, Joyce, Chua, Grace-Alyssa, Singh, Sajla, Hughes, Anastasia M, Ferrari, Emanuela, Ford, Jette, Chiu, Sung K, Stam, Ronald W, Kees, Ursula R, Malinge, Sébastien, Kotecha, Rishi S

“…Infants with -rearranged B-cell precursor acute lymphoblastic leukemia (ALL) have poor outcomes. There is an urgent need to identify novel agents to improve…”
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Core Patient-Reported Outcomes for Trials in Nephrology by Hughes, Anastasia, Scholes-Robertson, Nicole, Ju, Angela, Jauré, Allison

“…The outcomes reported in trials across all stages of chronic kidney disease (CKD) are highly variable and often do not include outcomes that are directly…”
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Perceptions of a prescription model for accessing nicotine vaping products: an examination of submissions made by self-reported e-cigarette users to an Australian consultation by Jongenelis, Michelle I, Robinson, Abby, Hughes, Anastasia, Pettigrew, Simone

“…Abstract In response to rapid and substantial increases in rates of e-cigarette use among young people, Australia’s Therapeutic Goods Administration (TGA) made…”
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DISSECTION OF THE PRE-B LEUKAEMIA BONE MARROW MICROENVIRONMENT by Cheung, Laurence, Hughes, Anastasia, Kees, Ursula, Tickner, Jennifer, Kotecha, Rishi

“…The microenvironments of leukaemia and cancer are critical for multiple stages of malignancies, and they are an attractive therapeutic target. Clinical studies…”
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Targeting Bone Marrow Microenvironment for Treatment of High-Risk B-Cell Acute Lymphoblastic Leukemia by Cheung, Laurence C, Trinder, Sarah, Hughes, Anastasia, Mullin, Benjamin, Rashid, Sarah, Yuan, Jinbo, Xu, Jiake, Duncan, Owen, Lock, Richard B., Malinge, Sebastien, Kuek, Vincent, Kotecha, Rishi Sury

“…Introduction B-cell acute lymphoblastic leukemia (B-ALL) is the most common form of cancer in children, accounting for approximately 20% of all pediatric…”
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WCN24-1599 PATIENT-REPORTED OUTCOMES MEASURES FOR LIFE PARTICIPATION IN PATIENTS WITH CHRONIC KIDNEY DISEASE: A SYSTEMATIC REVIEW by Hughes, Anastasia, Ju, Anglea, Cazzolli, Rosanna, Howell, Martin, Jaure, Allison

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WCN24-1587 PATIENT-REPORTED OUTCOMES MEASURES FOR PATIENTS WITH CHRONIC KIDNEY DISEASE: A SYSTEMATIC REVIEW by Hughes, Anastasia, Ju, Angela, Cazzolli, Rosanna, Howell, Martin, Jaure, Allison

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Patient, Parental, and Health Professional Perspectives on Growth in Children With CKD by Wu, Justin G., Guha, Chandana, Hughes, Anastasia, Torrisi, Luca G., Craig, Jonathan C., Sinha, Aditi, Dart, Allison, Eddy, Allison A., Bockenhauer, Detlef, Yap, Hui-Kim, Groothoff, Jaap, Alexander, Stephen I., Furth, Susan L., Samuel, Susan, Carter, Simon A., Walker, Amanda, Kausman, Joshua, Jaure, Allison

“…Growth failure is a common problem among children with chronic kidney disease (CKD). Reduced height is associated with psychosocial burden, social stigma, and…”
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Patient-Centered Research and Innovation in Nephrology by Hughes, Anastasia, Guha, Chandana, Sluiter, Amanda, Himmelfarb, Jonathan, Jauré, Allison

“…Patient involvement in research can improve the relevance of research, consequently enhancing the recruitment, retention, and uptake of interventions and…”
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Patient-reported outcome measures for life participation in patients with chronic kidney disease: a systematic review by Hughes, Anastasia, Ju, Angela, Cazzolli, Rosanna, Howell, Martin, Caskey, Fergus J, Elliott, Meghan J, Farragher, Janine, Greenwood, Sharlene, Levin, Adeera, Manera, Karine, Sluiter, Amanda, Teixeira-Pinto, Armando, Trimarchi, Hernan, Wang, Bill, Guha, Chandana, Wu, Rebecca, Jaure, Allison

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WCN24-1881 Interventions to improve life participation in kidney transplant recipients: a systematic review and meta-analysis by Hughes, Anastasia, Natale, Patrizia, Ju, Angela, Howell, Martin, Wong, Germaine, Teixeira-Pinto, Armando, Guha, Chandana, Sluiter, Amanda, Scholes-Robertson, Nicole, Craig, Jonathan C., Josephson, Michelle A., Strippoli, Giovanni, Jaure, Allison

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