Search Results - "Hugen, Niek"

Tumor Deposits in Colorectal Cancer: Improving the Value of Modern Staging-A Systematic Review and Meta-Analysis by Nagtegaal, Iris D, Knijn, Nikki, Hugen, Niek, Marshall, Helen C, Sugihara, Kenichi, Tot, Tibor, Ueno, Hideki, Quirke, Philip

“…Purpose Colorectal cancer (CRC) treatment is largely determined by tumor stage. Despite improvements made in the treatment of various types of metastatic…”
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The Impact of Primary Tumor Location in Synchronous Metastatic Colorectal Cancer: Differences in Metastatic Sites and Survival by Brouwer, Nelleke P. M., van der Kruijssen, Dave E. W., Hugen, Niek, de Hingh, Ignace H. J. T., Nagtegaal, Iris D., Verhoeven, Rob H. A., Koopman, Miriam, de Wilt, Johannes H. W.

“…Purpose We explored differences in survival between primary tumor locations, hereby focusing on the role of metastatic sites in synchronous metastatic…”
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Colorectal signet‐ring cell carcinoma: benefit from adjuvant chemotherapy but a poor prognostic factor by Hugen, Niek, Verhoeven, Rob H., Lemmens, Valery E, van Aart, Carola J., Elferink, Marloes A., Radema, Sandra A., Nagtegaal, Iris D., de Wilt, Johannes H.

“…Colorectal signet‐ring cell carcinoma (SRCC) has been associated with poor survival compared with mucinous adenocarcinoma (MC) and the more common…”
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Umbilical metastases: Real‐world data shows abysmal outcome by Hugen, Niek, Kanne, Heleen, Simmer, Femke, Water, Carlijn, Voorham, Quirinus J., Ho, Vincent K., Lemmens, Valery E., Simons, Michiel, Nagtegaal, Iris D.

“…Umbilical metastases form a clinical challenge, especially when they represent the first sign of malignant disease and the primary tumor is unknown. Our study…”
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Divergent Metastatic Patterns Between Subtypes of Thyroid Carcinoma Results From the Nationwide Dutch Pathology Registry by Hugen, Niek, Sloot, Yvette J E, Netea-Maier, Romana T, van de Water, Carlijn, Smit, Jan W A, Nagtegaal, Iris D, van Engen-van Grunsven, Ilse C H

“…Abstract Background Metastatic disease is the main cause of cancer-related mortality in thyroid carcinoma (TC) patients. Clinical studies have suggested…”
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Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network by Holmes, Kristen M, Annala, Matti, Chua, Corrine Y. X, Dunlap, Sarah M, Liu, Yuexin, Hugen, Niek, Moore, Lynette M, Cogdell, David, Hu, Limei, Nykter, Matti, Hess, Kenneth, Fuller, Gregory N, Zhang, Wei

“…Insulin-like growth factor-binding protein 2 (IGFBP2) is increasingly recognized as a glioma oncogene, emerging as a target for therapeutic intervention. In…”
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Assessment of Radiotherapy-Associated Angiosarcoma After Breast Cancer Treatment in a Dutch Population-Based Study by Rombouts, Anouk J M, Huising, Jonathan, Hugen, Niek, Siesling, Sabine, Poortmans, Philip Martin, Nagtegaal, Iris D, de Wilt, Johannes H W

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Unraveling the routes to distant metastases in colorectal cancer: Tumor deposits and lymph node metastases as the gateway by Brouwer, Nelleke Pietronella Maria, Oguz Erdogan, Ayse Selcen, Vliet, Shannon, Rutgers, Natasja, Knijn, Nikki, Lijnschoten, Gesina, Tan, Jessica Juliana, Wilt, Johannes Hendrik Willem, Hugen, Niek, Brown, Gina, Simmer, Femke, Nagtegaal, Iris Dionne

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Reply to Zhang, ‘Comment on: The mode of circumferential margin involvement in rectal cancer determines its impact on outcomes: A population-based study’ by Hugen, Niek, Loughrey, Maurice B., Nagtegaal, Iris D.

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Distinct metastatic patterns in colorectal cancer patients based on primary tumour location by Hugen, Niek, Nagtegaal, Iris D

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An overview of 25 years of incidence, treatment and outcome of colorectal cancer patients by Brouwer, Nelleke P.M., Bos, Amanda C.R.K., Lemmens, Valery E.P.P., Tanis, Pieter J., Hugen, Niek, Nagtegaal, Iris D., Wilt, Johannes H.W., Verhoeven, Rob H.A.

“…Regarding the continuous changes in the diagnostic process and treatment of colorectal cancer (CRC), it is important to evaluate long‐term trends which are…”
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Advances in the care of patients with mucinous colorectal cancer by Hugen, Niek, Brown, Gina, Glynne-Jones, Robert, de Wilt, Johannes H. W., Nagtegaal, Iris D.

“…Key Points Mucinous adenocarcinoma represents a distinct molecular and clinical tumour subtype, which should be recognized during the multimodality treatment…”
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Metastatic pattern in esophageal and gastric cancer: Influenced by site and histology by Verstegen, Moniek Hp, Harker, Mitchell, van de Water, Carlijn, van Dieren, Jolanda, Hugen, Niek, Nagtegaal, Iris D, Rosman, Camiel, van der Post, Rachel S

“…Detailed information on metastatic patterns in of patients with esophageal and gastric cancer is limited. Early recognition of metastases is important to avoid…”
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Tumour deposits are associated with worse survival than extranodal extension; a network meta-analysis on tumour nodules in colorectal cancer by Brouwer, Nelleke P M, van Vliet, Shannon, IntHout, Joanna, De Wilt, Johannes H W, Simmer, Femke, Hugen, Niek, Nagtegaal, Iris D

“…Lymph node metastases (LNM) play a central role in the tumour-node-metastasis (TNM) classification for colorectal cancer (CRC), with extranodal extension (ENE)…”
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The mode of circumferential margin involvement in rectal cancer determines its impact on outcomes: A population-based study by Hugen, Niek, Voorham, Quirinus J.M., Beets, Geerard L., Loughrey, Maurice B., Snaebjornsson, Petur, Nagtegaal, Iris D.

“…The clinical value of different modes of CRM involvement in rectal cancer patients is unclear. This study aims to determine the clinical impact of different…”
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Increased risk for second primary rectal cancer after pelvic radiation therapy by Rombouts, Anouk J.M., Hugen, Niek, Elferink, Marloes A.G., Poortmans, Philip M.P., Nagtegaal, Iris D., de Wilt, Johannes H.W.

“…The aim of this study was to analyse the association between pelvic radiation therapy (RT) and the development of rectal cancer as a second primary cancer…”
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Efficacy of an Autologous Blood Patch for Prolonged Air Leak: A Systematic Review by Hugen, Niek, Hekma, Edo J., Claessens, Niels J.M., Smit, Hans J.M., Reijnen, Michel M.P.J.

“…Prolonged air leak after pulmonary surgery remains a clinical challenge and sometimes needs surgical reintervention. An autologous blood patch (ABP) may…”
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Tumour-guided cell free tumour DNA analysis in peritoneal fluids of gastric cancer patients can detect occult peritoneal metastases by Van Der Sluis, Karen, van Sandick, Johanna, Vollebergh, Marieke, van Dieren, Jolanda, Hugen, Niek, Hartemink, Koen, Veenhof, Alexander, Verhoeven, Els, van der Berg, Jose, Snaebjornsson, Petur, van Wezel, Tom, Boelens, Mirjam, Kodach, Liudmila

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The Complexity of Shapes: How the Circularity of Tumor Nodules Affects Prognosis in Colorectal Cancer by Brouwer, Nelleke P M, Khan, Amjad, Bokhorst, John-Melle, Ayatollahi, Fazael, Hay, Jennifer, Ciompi, Francesco, Simmer, Femke, Hugen, Niek, de Wilt, Johannes H W, Berger, Martin D, Lugli, Alessandro, Zlobec, Inti, Edwards, Joanne, Nagtegaal, Iris D

“…The current stratification of tumor nodules in colorectal cancer (CRC) staging is subjective and leads to high interobserver variability. In this study, the…”
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Origin and outcome of metastatic tumours to the testes: a nationwide study by Woortman, Carmen, van Leenders, Geert J L H, Hugen, Niek, van Oijen, Martijn G H, Nagtegaal, Iris D

“…To perform a retrospective cohort analysis for metastatic tumours in the testes to explore the timing, presentation and prognosis of this particular type of…”
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