Search Results - "Huflejt, Margaret E"

Anti-carbohydrate antibodies of normal sera: Findings, surprises and challenges by Huflejt, Margaret E., Vuskovic, Marko, Vasiliu, Daniela, Xu, Hongyu, Obukhova, Polina, Shilova, Nadezhda, Tuzikov, Alexander, Galanina, Oxana, Arun, Banu, Lu, Karen, Bovin, Nicolai

“…We have used microchip format glycan array to characterize the individual carbohydrate recognition patterns by antibodies (Ab) in sera of 106 healthy donors…”
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Printed Covalent Glycan Array for Ligand Profiling of Diverse Glycan Binding Proteins by Blixt, Ola, Head, Steve, Mondala, Tony, Scanlan, Christopher, Huflejt, Margaret E., Alvarez, Richard, Bryan, Marian C., Fazio, Fabio, Calarese, Daniel, Stevens, James, Razi, Nahid, Stevens, David J., Skehel, John J., van Die, Irma, Burton, Dennis R., Wilson, Ian A., Cummings, Richard, Bovin, Nicolai, Wong, Chi-Huey, Paulson, James C.

“…Here we describe a glycan microarray constructed by using standard robotic microarray printing technology to couple amine functionalized glycans to an…”
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Serum antiglycan antibody detection of nonmucinous ovarian cancers by using a printed glycan array by Jacob, Francis, Goldstein, Darlene R., Bovin, Nicolai V., Pochechueva, Tatiana, Spengler, Marianne, Caduff, Rosemarie, Fink, Daniel, Vuskovic, Marko I., Huflejt, Margaret E., Heinzelmann-Schwarz, Viola

“…Epithelial ovarian cancer has the highest mortality rate among gynecological cancers. Altered glycosylation is associated with oncogenic transformation…”
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Galectin-4 in normal tissues and cancer by Huflejt, Margaret E, Leffler, Hakon

“…Galectin-4 belongs to a subfamily of galectins composed of two carbohydrate recognition domains within the same peptide chain. The two domains have all the…”
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Comparison of printed glycan array, suspension array and ELISA in the detection of human anti-glycan antibodies by Pochechueva, Tatiana, Jacob, Francis, Goldstein, Darlene R., Huflejt, Margaret E., Chinarev, Alexander, Caduff, Rosemarie, Fink, Daniel, Hacker, Neville, Bovin, Nicolai V., Heinzelmann-Schwarz, Viola

“…Anti-glycan antibodies represent a vast and yet insufficiently investigated subpopulation of naturally occurring and adaptive antibodies in humans. Recently, a…”
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Glycomics, Extracellular Matrix, and Anti-glycan Antibodies in Exfoliation Syndrome by Huflejt, Margaret E, Preiss, Jordan S, Thomson, Jennifer E, Gils, Ingrid M, Vuskovic, Marko I

“…Exfoliation syndrome (XFS) is considered to be a disease of extracellular matrix. Here we review key experimental evidence of aberrations in structure,…”
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Endogenous galectin-1 enforces class I–restricted TCR functional fate decisions in thymocytes by Liu, Scot D., Whiting, Chan C., Tomassian, Tamar, Pang, Mabel, Bissel, Stephanie J., Baum, Linda G., Mossine, Valeri V., Poirier, Françoise, Huflejt, Margaret E., Miceli, M. Carrie

“…During thymocyte development, the T-cell receptor (TCR) can discriminate major histocompatibility complex (MHC)/peptide ligands over a narrow range of…”
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The role of Thomsen-Friedenreich antigen in adhesion of human breast and prostate cancer cells to the endothelium by GLINSKY, Vladislav V, GLINSKY, Gennadi V, RITTENHOUSE-OLSON, Kate, HUFLEJT, Margaret E, GLINSKII, Olga V, DEUTSCHER, Susan L, QUINN, Thomas P

“…Interactions of metastatic cancer cells with vasculatory endothelium are critical during early stages of cancer metastasis. Understanding the molecular…”
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Natural Antibodies Against Sialoglycans by Shilova, Nadezhda, Huflejt, Margaret E, Vuskovic, Marko, Obukhova, Polina, Navakouski, Maksim, Khasbiullina, Nailya, Pazynina, Galina, Galanina, Oxana, Bazhenov, Alexey, Bovin, Nicolai

“…Natural antibodies, part of the innate immunity system, are produced at strictly regulated levels in normal sera without immunization and thus are part of the…”
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Processing and analysis of serum antibody binding signals from Printed Glycan Arrays for diagnostic and prognostic applications by Vuskovic, Marko I, Xu, Hongyu, Bovin, Nicolai V, Pass, Harvey I, Huflejt, Margaret E

“…Procedures for data preprocessing, quality control, data analysis, evaluation and visualization of the new high-throughput biomarker platform based on printed…”
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Glycoprotein 90K/MAC-2BP interacts with galectin-1 and mediates galectin-1-induced cell aggregation by TINARI, Nicola, KUWABARA, Ichiro, HUFLEJT, Margaret E, SHEN, Patrick F, IACOBELLI, Stefano, LIU, Fu-Tong

“…The glycoprotein 90K was originally described as a tumor-secreted antigen and subsequently found to have immunostimulatory activity as well as other possible…”
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Galectin‐3 binds lactosaminylated lipooligosaccharides from Neisseria gonorrhoeae and is selectively expressed by mucosal epithelial cells that are infected by John, Constance M., Jarvis, Gary A., Swanson, Karen V., Leffler, Hakon, Cooper, Morris D., Huflejt, Margaret E., Griffiss, J. McLeod

“…Summary Galectins are a family of β‐galactoside binding proteins that have been proposed as host receptors for bacteria because β‐galactoside carbohydrates are…”
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Changes in Membrane Lipid Composition during Saline Growth of the Fresh Water Cyanobacterium Synechococcus 6311 by Huflejt, Margaret E., Antoine Tremolieres, Bernard Pineau, Johanna K. Lang, John Hatheway, Packer, Lester

“…Growth of Synechococcus 6311 in the presence of 0.5 molar NaCl is accompanied by significant changes in membrane lipid composition. Upon transfer of the cells…”
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Impairment of Enzymic and Nonenzymic Antioxidants in Skin by UVB Irradiation by Fuchs, Jürgen, Huflejt, Margaret E., Rothfuss, Laurie M., Wilson, David S., Carcamo, Gerardo, Packer, Lester

“…Antioxidants may play a significant role in ameliorating or preventing photobiologic damage in skin that could lead to cutaneous disorders such as cancer and…”
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Complex Treatment of Amyotrophic Lateral Sclerosis Patient by Białkowska, Joanna, Mroczkowska, Dorota, Huflejt, Margaret E., Wojtkiewicz, Joanna, Siwek, Tomasz, Barczewska, Monika, Maksymowicz, Wojciech

“…Amyotrophic lateral sclerosis is a progressive and fatal degenerative neuromuscular disease with few if any treatment options and physical rehabilitation…”
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Strikingly Different Localization of Galectin-3 and Galectin-4 in Human Colon Adenocarcinoma T84 Cells by Huflejt, Margaret E., Jordan, Elizabeth T., Gitt, Michael A., Barondes, Samuel H., Leffler, Hakon

“…Two β-galactoside-binding proteins were found to be prominently expressed in the human colon adenocarcinoma T84 cell line. Cloning and sequencing of one, a…”
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Abstract POSTER-BIOL-1322: Natural anti-glycan IgM recognize P1 glycosphingolipid expressed on ovarian cancer cells by Jacob, Francis, Anugraham, Merrina, Pochechueva, Tatiana, Tse, Brian Wan-Chi, Alam, Shahidul, Guertler, Rea, Bovin, Nicolai V., Fedier, André, Hacker, Neville F., Huflejt, Margaret E., Packer, Nicolle, Heinzelmann-Schwarz, Viola A.

“…Abstract Recent research strongly suggests a role of plasma-derived anti-P1 antibodies (AGA) in ovarian cancer, as demonstrated by three independent…”
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Serum anti-glycan antibody detection of non-mucinous ovarian cancers by using a printed glycan array by Jacob, Francis, Goldstein, Darlene R., Bovin, Nicolai V., Pochechueva, Tatiana, Spengler, Marianne, Caduff, Rosemarie, Fink, Daniel, Vuskovic, Marko I., Huflejt, Margaret E., Heinzelmann-Schwarz, Viola

“…Epithelial Ovarian cancer has the highest mortality rate among gynaecological cancers. Altered glycosylation is associated with oncogenic transformation…”
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Effects of Thomsen-Friedenreich antigen-specific peptide P-30 on β-galactoside-mediated homotypic aggregation and adhesion to the endothelium of MDA-MB-435 human breast carcinoma cells by GLINSKY, V. V, HUFLEJT, M. E, GLINSKY, G. V, DEUTSCHER, S. L, QUINN, T. P

“…Both the ability of malignant cells to form multicellular aggregates via homotypic or heterotypic aggregation and their adhesion to the endothelium are…”
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Optimal Combination of Glycan-Based Serum Diagnostic Markers Which Maximize AUC by Marko I. Vuskovic, Haofei Fang, Harvey I. Pass, Margaret E. Huflejt

“…Recently a new high-throughput biomarker discovery platform based on printed glycan arrays (PGA) has emerged. PGAs are similar to DNA arrays but contain…”
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