Search Results - "Hufford, Charles D."

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    Antifungal Evaluation of Pseudolaric Acid B, a Major Constituent of Pseudolarix kaempferi by Li, Erguang, Clark, Alice M, Hufford, Charles D

    “…Pseudolaric acid B [1] was isolated and identified as the main antifungal constituent of Pseudolarix kaempferi using bioassay-directed fractionation…”
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    Copyrine alkaloids: synthesis, spectroscopic characterization, and antimycotic/antimycobacterial activity of A- and B-ring-functionalized sampangines by Peterson, John R, Zjawiony, Jordan K, Liu, Shihchih, Hufford, Charles D, Clark, Alice M, Rogers, Robin D

    Published in Journal of medicinal chemistry (01-10-1992)
    “…Several A- and B-ring-substituted sampangines were synthesized and evaluated for antifungal and antimycobacterial activity against AIDS-related opportunistic…”
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    Microbial Transformation of Benzosampangine by Orabi, Khaled Y, Clark, Alice M, Hufford, Charles D

    “…Microbial transformation studies of the synthetic antifungal alkaloid benzosampangine (1) have revealed that 1 is metabolized by a number of microorganisms…”
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    Microbial Metabolites of Ophiobolin A and Antimicrobial Evaluation of Ophiobolins by Li, Erguang, Clark, Alice M, Rotella, David P, Hufford, Charles D

    “…Ophiobolin A [1], 3-anhydroophiobolin A [2], ophiobolin B [3], and ophiobolin L [4] were isolated from fermentation broths of Cochliobolus heterostrophus…”
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    Use of microorganisms for the study of drug metabolism: an update by Clark, A M, Hufford, C D

    Published in Medicinal research reviews (01-09-1991)
    “…The use of microorganisms as tools in the study of drug metabolism appears to be gaining popularity. The selected examples cited here provide additional…”
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    Substituted indoloquinolines as new antifungal agents by ABLORDEPPEY, Seth Y, PINGCHEN FAN, SHOUMING LI, CLARK, Alice M, HUFFORD, Charles D

    Published in Bioorganic & medicinal chemistry (01-05-2002)
    “…Cryptolepine (2) possesses desirable properties to serve as a lead in developing new antifungal agents. Using SAR techniques, several analogues of cryptolepine…”
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    Bioactive (+)-manzamine A and (+)-8-hydroxymanzamine A tertiary bases and salts from Acanthostrongylophora ingens and their preparations by Samoylenko, Volodymyr, Khan, Shabana I, Jacoba, Melissa R, Tekwani, Babu L, Walker, Larry A, Hufford, Charles D, Muhammad, Ilias

    Published in Natural product communications (01-02-2009)
    “…The genus Acanthostrongylophora is famous for producing a wide array of manzamine alkaloids as natural hydrochloride salts. An examination of A. ingens has now…”
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    2-Hydroxy-5-(ethanolamino)-3-(10'-Z-pentadecenyl)-1, 4-benzoquinone, New Microbial Phase II Metabolite of Maesanin by ABOURASHED, Ehab A., EL-FERALY, Farouk S., KHAN, Ikhlas A., HUFFORD, Charles D.

    Published in Chemical & pharmaceutical bulletin (01-01-2000)
    “…The use of microbial models for biotransformation of the natural benzoquinone, maesanin (1), resulted in the isolation of an ethanolamine conjugate (5) from…”
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    NMR assignments of ellagic acid derivatives by Li, Xing-Cong, Elsohly, Hala N., Hufford, Charles D., Clark, Alice M.

    Published in Magnetic resonance in chemistry (01-11-1999)
    “…HMBC spectroscopy optimized for small couplings was employed to determine the four‐bond and two‐bond proton carbon correlations on the aromatic rings of…”
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    The use of microorganisms for the study of drug metabolism by Clark, A M, McChesney, J D, Hufford, C D

    Published in Medicinal research reviews (01-04-1985)
    “…The potential for the use of microorganisms as tools in the study of drug metabolism appears to be unlimited. The selected examples cited here are only the…”
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    Antimicrobial properties of Honduran medicinal plants by Lentz, David L, Clark, Alice M, Hufford, Charles D, Meurer-Grimes, Barbara, Passreiter, Claus M, Cordero, Javier, Ibrahimi, Omar, Okunade, Adewole L

    Published in Journal of ethnopharmacology (01-12-1998)
    “…Ninety-two plants used in the traditional pharmacopoeia of the Pech and neighboring Mestizo peoples of central Honduras are reported. The results of in vitro…”
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    Clinic at the Health Food Store? Employee Recommendations and Product Analysis by Glisson, James K., Rogers, Holly E., Abourashed, Ehab A., Ogletree, Richard, Hufford, Charles D., Khan, Ikhlas

    Published in Pharmacotherapy (01-01-2003)
    “…Study Objectives. To determine what products health food store employees recommend for depression, to analyze the content of these products based on label…”
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    Antifungal Activity of Trillium grandiflorum Constituents by Hufford, Charles D, Liu, Shihchih, Clark, Alice M

    “…EtOH extracts of the rhizomes and aboveground portion of Trillium grandiflorum showed significant antifungal activity. Bioassay directed fractionation has led…”
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    Alkaloids from Haplophyllum tuberculatum by Al-Rehaily, Adnan J., Al-Howiriny, Tawfeq A., Ahmad, Mohammad S., Al-Yahya, Mohammad A., El-Feraly, Farouk S., Hufford, Charles D., McPhail, Andrew T.

    Published in Phytochemistry (Oxford) (01-06-2001)
    “…Two new alkaloids, haplotubinone ( 3 ) and haplotubine ( 4 ), were isolated from the aerial parts of Haplophyllum tuberculatum together with the known lignan…”
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    Microbial Transformation of Sampangine by Orabi, Khaled Y, Li, Erguang, Clark, Alice M, Hufford, Charles D

    “…Microbial transformation studies of the antifungal alkaloid sampangine (2) have revealed that it is metabolized by a number of microorganisms. Using a standard…”
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    Metabolism of antimalarial sesquiterpene lactones by Lee, I S, Hufford, C D

    “…Metabolism of artemisinin derivatives, which are antimalarial sesquiterpenes, appeared to lead to the production of the more polar metabolites in general…”
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    Microbial metabolism of bornaprine, 3-(diethylamino)propyl 2-phenylbicyclo[2.2.1]heptane-2-carboxylate by Elmarakby, S A, Clark, A M, Baker, J K, Hufford, C D

    Published in Journal of pharmaceutical sciences (01-06-1986)
    “…Metabolism studies of the anticholinergic drug, bornaprine [3-(diethylamino)propyl 2-phenylbicyclo[2.2.1]heptane-2-carboxylate, an epimeric mixture], in rats,…”
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    Characterization of the Major Metabolite of Sampangine in Rats by Orabi, Khaled Y, Walker, Larry A, Clark, Alice M, Hufford, Charles D

    “…Sampangine (1) is a plant-derived antifungal copyrine alkaloid extracted from the stem bark of Cananga odorata. Although it possesses potent in vitro…”
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