Search Results - "Huff, A C"

Epidemiology and Outcomes of Clostridium difficile Infections in Hematopoietic Stem Cell Transplant Recipients by Alonso, Carolyn D., Treadway, Suzanne B., Hanna, David B., Huff, Carol Ann, Neofytos, Dionissios, Carroll, Karen C., Marr, Kieren A.

“…Background. Clostridium difficile is the leading cause of infectious diarrhea among hospitalized patients and is a major concern for patients undergoing…”
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Salvage transplantation for allograft failure using fludarabine and alemtuzumab as conditioning regimen by Bolaños-Meade, J, Luznik, L, Muth, M, Matsui, W H, Huff, C A, Smith, B D, Levy, M Y, Kasamon, Y L, Swinnen, L J, Powell, J D, Brodsky, R A, Ambinder, R F, Jones, R J, Fuchs, E J

“…Graft failure after allogeneic blood or marrow transplantation, although generally uncommon, can be a devastating complication. This report includes the…”
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Identification of control elements 3' to the human keratin 1 gene that regulate cell type and differentiation-specific expression by HUFF, C. A, YUSPA, S. H, ROSENTHAL, D

“…To define DNA regulatory elements that mediate the response of the keratin 1 (K1) gene to Ca(2+)-induced differentiation, regions spanning the 5'- and…”
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Characterization of clonogenic multiple myeloma cells by Matsui, William, Huff, Carol Ann, Wang, Qiuju, Malehorn, Matthew T., Barber, James, Tanhehco, Yvette, Smith, B. Douglas, Civin, Curt I., Jones, Richard J.

“…The identity of the cells responsible for the initiation and maintenance of multiple myeloma (MM) remains unclear largely because of the difficulty growing MM…”
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Recrudescence of Cutaneous Mycobacterium haemophilum Lesions Following Tetanus Immunization by Gibson, Michael K., Villano, Stephen A., Huff, Carol Ann

“…Mycobacterium haemophilum is increasingly recognized as a cause of cutaneous, joint, and pulmonary infections in immuno-compromised hosts. We describe a…”
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Evidence for a common mechanism of action for antitumor and antibacterial agents that inhibit type II DNA topoisomerases by Huff, A C, Kreuzer, K N

“…Numerous antitumor and antibacterial agents inhibit type II DNA topoisomerases, yielding, in each case, a complex of enzyme covalently bound to cleaved DNA. We…”
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Autoproteolysis of the small subunit of calcium-dependent protease II activates and regulates protease activity by DeMartino, G N, Huff, C A, Croall, D E

“…Calcium-dependent protease II (CDP-II) from bovine heart is a heterodimer with subunit molecular weights of 80,000 and 26,000. Previous studies have…”
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DNA damage at thymine N-3 abolishes base-pairing capacity during DNA synthesis by Huff, A C, Topal, M D

“…3-Methylthymine was synthesized into DNA copolymers and deoxynucleoside triphosphate to study its effect on DNA synthesis by the Klenow fragment of Escherichia…”
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Bacteriophage T4 DNA Topoisomerase is the Target of Antitumor Agent 4′-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) in T4-Infected Escherichia coli by Huff, Anne C., Leatherwood, Janet K., Kreuzer, Kenneth N.

“…The mammalian type II DNA topoisomerase has been proposed to be the intracellular target of a variety of antitumor agents, including m-AMSA…”
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Oral Selinexor–Dexamethasone for Triple-Class Refractory Multiple Myeloma by Chari, Ajai, Vogl, Dan T, Gavriatopoulou, Maria, Nooka, Ajay K, Yee, Andrew J, Huff, Carol A, Moreau, Philippe, Dingli, David, Cole, Craig, Lonial, Sagar, Dimopoulos, Meletios, Stewart, A. Keith, Richter, Joshua, Vij, Ravi, Tuchman, Sascha, Raab, Marc S, Weisel, Katja C, Delforge, Michel, Cornell, Robert F, Kaminetzky, David, Hoffman, James E, Costa, Luciano J, Parker, Terri L, Levy, Moshe, Schreder, Martin, Meuleman, Nathalie, Frenzel, Laurent, Mohty, Mohamad, Choquet, Sylvain, Schiller, Gary, Comenzo, Raymond L, Engelhardt, Monika, Illmer, Thomas, Vlummens, Philip, Doyen, Chantal, Facon, Thierry, Karlin, Lionel, Perrot, Aurore, Podar, Klaus, Kauffman, Michael G, Shacham, Sharon, Li, Lingling, Tang, Shijie, Picklesimer, Carla, Saint-Martin, Jean-Richard, Crochiere, Marsha, Chang, Hua, Parekh, Samir, Landesman, Yosef, Shah, Jatin, Richardson, Paul G, Jagannath, Sundar

“…Selinexor, a drug that inhibits nuclear export of tumor suppressor proteins, was tested in a phase 2 trial involving patients with myeloma whose disease had…”
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Changes in Photo-Aged Human Skin Following Topical Application of All-Trans Retinoic Acid by Rosenthal, Dean S, Roop, Dennis R, Huff, Carol A, Weiss, Jonathan S, Ellis, Charles N, Hamilton, Ted, Voorhees, John J, Yuspa, Stuart H

“…Although topical applications of retinoids on rodents and humans have been shown to cause epidermal hyperplasia, a detailed study of the influence of retinoids…”
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DNA sequence preferences at sites cleaved by human DNA topoisomerase II in response to novel quinolone derivatives by Huff, A C, Robinson, R G, Evans, A C, Selander, K N, Wentland, M P, Rake, J B, Coughlin, S A

“…We have examined the DNA cleavage site specificity of human type II DNA topoisomerase in the presence of each of five novel quinolone derivatives. Each…”
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Isolation and characterization of monoclonal antibodies to a recombinant human topoisomerase II polypeptide by Robinson, R G, Rapp, L, Bowdish, K J, Graham, M A, Huff, A C, Coughlin, S A

“…We have produced two murine monoclonal antibodies (SWT3D1 and SWR1C2) to a recombinant polypeptide corresponding to the carboxyl-terminal one-third (amino acid…”
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A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes by Rosenthal, D S, Steinert, P M, Chung, S, Huff, C A, Johnson, J, Yuspa, S H, Roop, D R

“…Keratins K1 and K10 represent the major differentiation products of the maturing epidermal keratinocytes. Primary epidermal cell cultures from newborn K1…”
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Ibrutinib alone or with dexamethasone for relapsed or relapsed and refractory multiple myeloma: phase 2 trial results by Richardson, Paul G., Bensinger, William I., Huff, Carol Ann, Costello, Caitlin L., Lendvai, Nikoletta, Berdeja, Jesus G., Anderson, Larry D., Siegel, David S., Lebovic, Daniel, Jagannath, Sundar, Laubach, Jacob P., Stockerl‐Goldstein, Keith E., Kwei, Long, Clow, Fong, Elias, Laurence, Salman, Zeena, Graef, Thorsten, Bilotti, Elizabeth, Vij, Ravi

“…Summary Novel therapies with unique new targets are needed for patients who are relapsed/refractory to current treatments for multiple myeloma. Ibrutinib is a…”
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The paradox of response and survival in cancer therapeutics by Huff, Carol Ann, Matsui, William, Smith, B. Douglas, Jones, Richard J.

“…Although most patients with cancer respond to therapy, few are cured. Moreover, objective clinical responses to treatment often do not even translate into…”
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Inheritance of resistance in corn (Zea mays) to gray leaf spot by Huff, C.A, Ayers, J.E, Hill, R.R. Jr

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Effects of imatinib and interferon on primitive chronic myeloid leukaemia progenitors by Angstreich, Greg R., Matsui, William, Huff, Carol Ann, Vala, Milada S., Barber, James, Hawkins, Anita L., Griffin, Constance A., Douglas Smith, B., Jones, Richard J.

“…Summary Imatinib has impressive activity against chronic myeloid leukaemia (CML), but does not appear to completely eradicate the disease. Although responses…”
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Mutational alteration of the breakage/resealing subunit of bacteriophage T4 DNA topoisomerase confers resistance to antitumor agent m-AMSA by Huff, A C, Ward, 4th, R E, Kreuzer, K N

“…Bacteriophage T4 provides a simple model system in which to examine the mechanism of action of antitumor agents that have been proposed to attack type II DNA…”
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Strategies to eliminate cancer stem cells: Clinical implications by Huff, Carol Ann, Matsui, William H., Douglas Smith, B., Jones, Richard J.

“…Over the past two decades, major advances in our understanding of cancer have translated into only modest increments in survival for the majority of cancer…”
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