Search Results - "Huey, Daniel J."

Unlike Bone, Cartilage Regeneration Remains Elusive by Huey, Daniel J., Hu, Jerry C., Athanasiou, Kyriacos A.

“…Articular cartilage was predicted to be one of the first tissues to successfully be regenerated, but this proved incorrect. In contrast, bone (but also…”
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TGF‐β1, GDF‐5, and BMP‐2 Stimulation Induces Chondrogenesis in Expanded Human Articular Chondrocytes and Marrow‐Derived Stromal Cells by Murphy, Meghan K., Huey, Daniel J., Hu, Jerry C., Athanasiou, Kyriacos A.

“…Replacement of degenerated cartilage with cell‐based cartilage products may offer a long‐term solution to halt arthritis' degenerative progression…”
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Tension-compression loading with chemical stimulation results in additive increases to functional properties of anatomic meniscal constructs by Huey, Daniel J, Athanasiou, Kyriacos A

“…This study aimed to improve the functional properties of anatomically-shaped meniscus constructs through simultaneous tension and compression mechanical…”
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Functional self-assembled neocartilage as part of a biphasic osteochondral construct by Brown, Wendy E, Huey, Daniel J, Hu, Jerry C, Athanasiou, Kyriacos A

“…Bone-to-bone integration can be obtained by osteoconductive ceramics such as hydroxyapatite (HAp) and beta-tricalcium phosphate (β-TCP), but…”
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Enhancing post-expansion chondrogenic potential of costochondral cells in self-assembled neocartilage by Murphy, Meghan K, Huey, Daniel J, Reimer, Andrew J, Hu, Jerry C, Athanasiou, Kyriacos A

“…The insufficient healing capacity of articular cartilage necessitates mechanically functional biologic tissue replacements. Using cells to form biomimetic…”
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Chondrogenically tuned expansion enhances the cartilaginous matrix-forming capabilities of primary, adult, leporine chondrocytes by Huey, Daniel J, Hu, Jerry C, Athanasiou, Kyriacos A

“…When expanded through passage, chondrocytes lose their ability to produce high-quality cartilaginous matrix. This study attempts to improve the properties of…”
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TGF- beta 1, GDF-5, and BMP-2 Stimulation Induces Chondrogenesis in Expanded Human Articular Chondrocytes and Marrow-Derived Stromal Cells by Murphy, Meghan K, Huey, Daniel J, Hu, Jerry C, Athanasiou, Kyriacos A

“…Abstract Replacement of degenerated cartilage with cell-based cartilage products may offer a long-term solution to halt arthritis' degenerative progression…”
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Maturational growth of self-assembled, functional menisci as a result of TGF-β1 and enzymatic chondroitinase-ABC stimulation by Huey, Daniel J, Athanasiou, Kyriacos A

“…Abstract Replacement of the knee meniscus requires a material possessing adequate geometrical and biomechanical properties. Meniscal tissue engineering…”
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Maturational growth of self-assembled, functional menisci as a result of TGF- beta 1 and enzymatic chondroitinase-ABC stimulation by Huey, Daniel J, Athanasiou, Kyriacos A

“…Replacement of the knee meniscus requires a material possessing adequate geometrical and biomechanical properties. Meniscal tissue engineering attempts have…”
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Engineering biomechanically functional neocartilage derived from expanded articular chondrocytes through the manipulation of cell‐seeding density and dexamethasone concentration by Huang, Brian J., Huey, Daniel J., Hu, Jerry C., Athanasiou, Kyriacos A.

“…Recent work has established methods to engineer self‐assembled, scaffold‐free neocartilage from an expanded articular chondrocyte (AC) cell source. In…”
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Regenerating Mandibular Bone Using rhBMP-2: Part 1-Immediate Reconstruction of Segmental Mandibulectomies by Arzi, Boaz, Verstraete, Frank J.M., Huey, Daniel J., Cissell, Derek D., Athanasiou, Kyriacos A.

“…Objective To describe a surgical technique using a regenerative approach and internal fixation for immediate reconstruction of critical size bone defects after…”
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Alteration of the fibrocartilaginous nature of scaffoldless constructs formed from leporine meniscus cells and chondrocytes through manipulation of culture and processing conditions by Huey, Daniel J, Athanasiou, Kyriacos A

“…Articular cartilage and the menisci of the knee joint lack intrinsic repair capacity; thus, injuries to these tissues result in eventual osteoarthrotic changes…”
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Regenerating Mandibular Bone Using rhBMP-2: Part 2-Treatment of Chronic, Defect Non-Union Fractures by Verstraete, Frank J.M., Arzi, Boaz, Huey, Daniel J., Cissell, Derek D., Athanasiou, Kyriacos A.

“…Objective To describe a surgical technique using a regenerative approach and internal fixation for reconstruction of critical size bone defect non‐union…”
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A proposed model of naturally occurring osteoarthritis in the domestic rabbit by Arzi, Boaz, Wisner, Erik R., Huey, Daniel J., Kass, Philip H., Hu, Jerry, Athanasiou, Kyriacos A.

“…Osteoarthritis affects one in eight American adults over the age of 25 y and is a leading cause of chronic disability in the US. Translational research to…”
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Immunogenicity of bovine and leporine articular chondrocytes and meniscus cells by Huey, Daniel J, Sanchez-Adams, Johannah, Willard, Vincent P, Athanasiou, Kyriacos A

“…Immune rejection is a major concern for any allogeneic or xenogeneic graft. For in vivo investigations of cartilage tissue engineering strategies, small animal…”
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temporomandibular joint disc of Asian elephant (Elephas maximus) and African elephant (Loxodonta africana) by Arzi, Boaz, Willard, Vincent P, Huey, Daniel J, Verstraete, Frank J. M, Vapniarsky-Arzi, Natalia, Athanasiou, Kyriacos A

“…The temporomandibular joint (TMJ) is a synovial articulation between the mandibular head of the condylar process of the mandible and the mandibular fossa of…”
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TGF-[beta]1, GDF-5, and BMP-2 Stimulation Induces Chondrogenesis in Expanded Human Articular Chondrocytes and Marrow-Derived Stromal Cells by Murphy, Meghan K, Huey, Daniel J, Hu, Jerry C, Athanasiou, Kyriacos A

“…Replacement of degenerated cartilage with cell-based cartilage products may offer a long-term solution to halt arthritis' degenerative progression…”
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Engineering biomechanically functional neocartilage derived from expanded articular chondrocytes through the manipulation of cell-seeding density and dexamethasone concentration: Engineering biomechanically functional cartilage by Huang, Brian J., Huey, Daniel J., Hu, Jerry C., Athanasiou, Kyriacos A.

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Unlike Bone, Cartilage Regeneration Remains Elusive : BIOMATERIALS by HUEY, Daniel J, HU, Jerry C, ATHANASIOU, Kyriacos A

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Naturally-occurring osteoarthritis in the domestic rabbit: possible implications for bioengineering research by Arzi, Boaz, Wisner, Erik R., Huey, Daniel J., Kass, Philip H., Hu, Jerry, Athanasiou, Kyriacos A.

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