Search Results - "Huettner, Soeren S"

The natural compound atraric acid suppresses androgen-regulated neo-angiogenesis of castration-resistant prostate cancer through angiopoietin 2 by Ehsani, Marzieh, Bartsch, Sophie, Rasa, Seyed Mohammad Mahdi, Dittmann, Jessica, Pungsrinont, Thanakorn, Neubert, Laura, Huettner, Soeren S., Kotolloshi, Roland, Schindler, Katrin, Ahmad, Aya, Mosig, Alexander S., Adam, Lisa, Ori, Alessandro, Neri, Francesco, Berndt, Alexander, Grimm, Marc-Oliver, Baniahmad, Aria

“…Castration-resistant prostate cancer (CRPC) is an aggressive lethal form of prostate cancer (PCa). Atraric acid (AA) not only inhibits the wild-type androgen…”
Get full text

Supraphysiological androgen levels induce cellular senescence in human prostate cancer cells through the Src-Akt pathway by Roediger, Julia, Hessenkemper, Wiebke, Bartsch, Sophie, Manvelyan, Marina, Huettner, Soeren S, Liehr, Thomas, Esmaeili, Mohsen, Foller, Susan, Petersen, Iver, Grimm, Marc-Oliver, Baniahmad, Aria

“…Prostate cancer (PCa) is the second leading cause of cancer mortality of men in Western countries. The androgen receptor (AR) and AR-agonists (androgens) are…”
Get full text

Adult stem cells at work: regenerating skeletal muscle by Schmidt, Manuel, Schüler, Svenja C., Hüttner, Sören S., von Eyss, Björn, von Maltzahn, Julia

“…Skeletal muscle regeneration is a finely tuned process involving the activation of various cellular and molecular processes. Satellite cells, the stem cells of…”
Get full text

A dysfunctional miR-1-TRPS1-MYOG axis drives ERMS by suppressing terminal myogenic differentiation by Hüttner, Sören S., Henze, Henriette, Elster, Dana, Koch, Philipp, Anderer, Ursula, von Eyss, Björn, von Maltzahn, Julia

“…Rhabdomyosarcoma is the most common pediatric soft tissue tumor, comprising two major subtypes: the PAX3/7-FOXO1 fusion-negative embryonal and the PAX3/7-FOXO1…”
Get full text

Single Myofiber Culture Assay for the Assessment of Adult Muscle Stem Cell Functionality Ex Vivo by Hüttner, Sören S, Hayn, Christian, Ahrens, Hellen E, Schmidt, Manuel, Henze, Henriette, von Maltzahn, Julia

“…Adult skeletal muscle tissue harbors a stem cell population that is indispensable for its ability to regenerate. Upon muscle damage, muscle stem cells leave…”
Get more information

Thyroid Hormone Transporters MCT8 and OATP1C1 Control Skeletal Muscle Regeneration by Mayerl, Steffen, Schmidt, Manuel, Doycheva, Denica, Darras, Veerle M., Hüttner, Sören S., Boelen, Anita, Visser, Theo J., Kaether, Christoph, Heuer, Heike, von Maltzahn, Julia

“…Thyroid hormone (TH) transporters are required for the transmembrane passage of TH in target cells. In humans, inactivating mutations in the TH transporter…”
Get full text

Denervation alters the secretome of myofibers and thereby affects muscle stem cell lineage progression and functionality by Henze, Henriette, Hüttner, Sören S., Koch, Philipp, Schüler, Svenja C., Groth, Marco, von Eyss, Björn, von Maltzahn, Julia

“…Skeletal muscle function crucially depends on innervation while repair of skeletal muscle relies on resident muscle stem cells (MuSCs). However, it is poorly…”
Get full text