Search Results - "Huet, Sébastien"

Serine-linked PARP1 auto-modification controls PARP inhibitor response by Prokhorova, Evgeniia, Zobel, Florian, Smith, Rebecca, Zentout, Siham, Gibbs-Seymour, Ian, Schützenhofer, Kira, Peters, Alessandra, Groslambert, Joséphine, Zorzini, Valentina, Agnew, Thomas, Brognard, John, Nielsen, Michael L., Ahel, Dragana, Huet, Sébastien, Suskiewicz, Marcin J., Ahel, Ivan

“…Poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 are recruited and activated by DNA damage, resulting in ADP-ribosylation at numerous sites, both within PARP1…”
Get full text

CHD3 and CHD4 recruitment and chromatin remodeling activity at DNA breaks is promoted by early poly(ADP-ribose)-dependent chromatin relaxation by Smith, Rebecca, Sellou, Hafida, Chapuis, Catherine, Huet, Sébastien, Timinszky, Gyula

“…Abstract One of the first events to occur upon DNA damage is the local opening of the compact chromatin architecture, facilitating access of repair proteins to…”
Get full text

RhoA- and Cdc42-induced antagonistic forces underlie symmetry breaking and spindle rotation in mouse oocytes by Dehapiot, Benoit, Clément, Raphaël, Bourdais, Anne, Carrière, Virginie, Huet, Sébastien, Halet, Guillaume

“…Mammalian oocyte meiotic divisions are highly asymmetric and produce a large haploid gamete and 2 small polar bodies. This relies on the ability of the cell to…”
Get full text

The RNA export factor Mex67 functions as a mobile nucleoporin by Derrer, Carina Patrizia, Mancini, Roberta, Vallotton, Pascal, Huet, Sébastien, Weis, Karsten, Dultz, Elisa

“…The RNA export factor Mex67 is essential for the transport of mRNA through the nuclear pore complex (NPC) in yeast, but the molecular mechanism of this export…”
Get full text

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks by Rother, Magdalena B., Pellegrino, Stefania, Smith, Rebecca, Gatti, Marco, Meisenberg, Cornelia, Wiegant, Wouter W., Luijsterburg, Martijn S., Imhof, Ralph, Downs, Jessica A., Vertegaal, Alfred C. O., Huet, Sébastien, Altmeyer, Matthias, van Attikum, Haico

“…Chromatin structure is dynamically reorganized at multiple levels in response to DNA double-strand breaks (DSBs). Yet, how the different steps of chromatin…”
Get full text

Lost in the Crowd: How Does Human 8-Oxoguanine DNA Glycosylase 1 (OGG1) Find 8-Oxoguanine in the Genome? by D'Augustin, Ostiane, Huet, Sébastien, Campalans, Anna, Radicella, Juan Pablo

“…The most frequent DNA lesion resulting from an oxidative stress is 7,8-dihydro-8-oxoguanine (8-oxoG). 8-oxoG is a premutagenic base modification due to its…”
Get full text

Multi-Scale Imaging of the Dynamic Organization of Chromatin by García Fernández, Fabiola, Huet, Sébastien, Miné-Hattab, Judith

“…Chromatin is now regarded as a heterogeneous and dynamic structure occupying a non-random position within the cell nucleus, where it plays a key role in…”
Get full text

Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining by Singh, Jenny Kaur, Smith, Rebecca, Rother, Magdalena B., de Groot, Anton J. L., Wiegant, Wouter W., Vreeken, Kees, D’Augustin, Ostiane, Kim, Robbert Q., Qian, Haibin, Krawczyk, Przemek M., González-Prieto, Román, Vertegaal, Alfred C. O., Lamers, Meindert, Huet, Sébastien, van Attikum, Haico

“…DNA double-strand breaks (DSBs) are among the most deleterious types of DNA damage as they can lead to mutations and chromosomal rearrangements, which underlie…”
Get full text

The recruitment of ACF1 and SMARCA5 to DNA lesions relies on ADP-ribosylation dependent chromatin unfolding by Pinto Jurado, Eva, Smith, Rebecca, Bigot, Nicolas, Chapuis, Catherine, Timinszky, Gyula, Huet, Sébastien

“…ADP-ribosylation signaling orchestrates the recruitment of various repair actors and chromatin remodeling processes promoting access to lesions during the…”
Get full text

Nuclear Import and Assembly of Influenza A Virus RNA Polymerase Studied in Live Cells by Fluorescence Cross-Correlation Spectroscopy by HUET, Sébastien, AVILOV, Sergiy V, FERBITZ, Lars, DAIGLE, Nathalie, CUSACK, Stephen, ELLENBERG, Jan

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Spatio-temporal dynamics of the DNA glycosylase OGG1 in finding and processing 8-oxoguanine by Cintori, Luana, Di Guilmi, Anne-Marie, Canitrot, Yvan, Huet, Sebastien, Campalans, Anna

“…OGG1 is the DNA glycosylase responsible for the removal of the oxidative lesion 8-oxoguanine (8-oxoG) from DNA. The recognition of this lesion by OGG1 is a…”
Get full text

The N-terminal domain of TET1 promotes the formation of dense chromatin regions refractory to transcription by Lejart, Audrey, Zentout, Siham, Chapuis, Catherine, D’Augustin, Ostiane, Smith, Rebecca, Salbert, Gilles, Huet, Sébastien

“…TET (ten-eleven translocation) enzymes initiate active cytosine demethylation via the oxidation of 5-methylcytosine. TET1 is composed of a C-terminal domain,…”
Get full text

A fractal model for nuclear organization: current evidence and biological implications by Bancaud, Aurélien, Lavelle, Christophe, Huet, Sébastien, Ellenberg, Jan

“…Chromatin is a multiscale structure on which transcription, replication, recombination and repair of the genome occur. To fully understand any of these…”
Get full text

Differential Pigment Accumulation in Carrot Leaves and Roots during Two Growing Periods by Perrin, Florent, Brahem, Marwa, Dubois-Laurent, Cécile, Huet, Sébastien, Jourdan, Matthieu, Geoffriau, Emmanuel, Peltier, Didier, Gagné, Séverine

“…Carotenoids are important secondary metabolites involved in plant growth and nutritional quality of vegetable crops. These pigments are highly accumulated in…”
Get full text

Crowded chromatin is not sufficient for heterochromatin formation and not required for its maintenance by Walter, Andreas, Chapuis, Catherine, Huet, Sébastien, Ellenberg, Jan

“…In contrast to cytoplasmic organelles, which are usually separated from the rest of the cell by phospholipid membranes, nuclear compartments are readily…”
Get full text

New Methodologies to Study DNA Repair Processes in Space and Time Within Living Cells by Zentout, Siham, Smith, Rebecca, Jacquier, Marine, Huet, Sébastien

“…DNA repair requires a coordinated effort from an array of factors that play different roles in the DNA damage response from recognizing and signaling the…”
Get full text

Multisite evaluation of phenotypic plasticity for specialized metabolites, some involved in carrot quality and disease resistance by Chevalier, Wilfried, Moussa, Sitti-Anlati, Medeiros Netto Ottoni, Miguel, Dubois-Laurent, Cécile, Huet, Sébastien, Aubert, Christophe, Desnoues, Elsa, Navez, Brigitte, Cottet, Valentine, Chalot, Guillaume, Jost, Michel, Barrot, Laure, Freymark, Gerald, Uittenbogaard, Maarten, Chaniet, François, Suel, Anita, Bouvier Merlet, Marie-Hélène, Hamama, Latifa, Le Clerc, Valérie, Briard, Mathilde, Peltier, Didier, Geoffriau, Emmanuel

“…Renewed consumer demand motivates the nutritional and sensory quality improvement of fruits and vegetables. Specialized metabolites being largely involved in…”
Get full text

'Should I stay or should I go?': myosin V function in organelle trafficking by Desnos, Claire, Huet, Sébastien, Darchen, François

“…Actin‐ and microtubule‐based motors can propel different cargos along filaments. Within cells, they control the distribution of membrane‐bound compartments by…”
Get full text

Poly(ADP-Ribose)-Dependent Chromatin Remodeling in DNA Repair by Lebeaupin, Théo, Smith, Rebecca, Huet, Sébastien, Timinszky, Gyula

“…The tightly packed and dynamic structure of chromatin can undergo major reorganization in response to endogenous or exogenous stimuli, such as the regulation…”
Get more information

Formation of the Nuclear Envelope Permeability Barrier Studied by Sequential Photoswitching and Flux Analysis by Dultz, Elisa, Huet, Sébastien, Ellenberg, Jan

“…In higher eukaryotes, the nuclear envelope breaks down during mitosis. It reforms during telophase, and nuclear import is reestablished within <10 min after…”
Get full text