Search Results - "Huerta Yépez, Sara"

Application of computational methods for anticancer drug discovery, design, and optimization by Diego Prada-Gracia, Sara Huerta-Yépez, Liliana M. Moreno-Vargas

“…Developing a novel drug is a complex, risky, expensive and time-consuming venture. It is estimated that the conventional drug discovery process ending with a…”
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Role of diets rich in omega-3 and omega-6 in the development of cancer by Sara Huerta-Yépez, Ana B. Tirado-Rodriguez, Oliver Hankinson

“…Over the past decade, some studies have addressed the therapeutic effects of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) and the opposite effects of…”
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Necrotic Cell Death and Inflammasome NLRP3 Activity in Mycobacterium bovis-Infected Bovine Macrophages by Escobar-Chavarría, Omar, Benitez-Guzman, Alejandro, Jiménez-Vázquez, Itzel, Carrisoza-Urbina, Jacobo, Arriaga-Pizano, Lourdes, Huerta-Yépez, Sara, Baay-Guzmán, Guillermina, Gutiérrez-Pabello, José A.

“…Mycobacterium bovis is a facultative intracellular bacterium that produces cellular necrosis in granulomatous lesions in bovines. Although M. bovis-induced…”
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Toll-Like Receptors and Cytokines are Upregulated during Helicobacter pylori Infection in Children by Lagunes-Servin, Hugo, Torres, Javier, Maldonado-Bernal, Carmen, Pérez-Rodríguez, Martha, Huerta-Yépez, Sara, Madrazo de la Garza, Armando, Muñoz-Pérez, Leopoldo, Flores-Luna, Lourdes, Ramón-García, Guillermo, Camorlinga-Ponce, Margarita

“…Background and Aim Helicobacter pylori infection is mainly acquired during childhood, and establishes a chronic infection that may lead to peptic ulcer or…”
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Allergies: diseases closely related to cancer by Belén Tirado-Rodríguez, Sara Huerta-Yépez

“…Allergies are hypersensitivity reactions that occur through specific type Th2 immunological mechanisms characterized by different soluble mediators, as well as…”
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The Involvement of Polyunsaturated Fatty Acids in Apoptosis Mechanisms and Their Implications in Cancer by Montecillo-Aguado, Mayra, Tirado-Rodriguez, Belen, Huerta-Yepez, Sara

“…Cancer is a significant global public health issue and, despite advancements in detection and treatment, the prognosis remains poor. Cancer is a complex…”
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The Role of PTEN in Chemoresistance Mediated by the HIF-1α/YY1 Axis in Pediatric Acute Lymphoblastic Leukemia by Antonio-Andres, Gabriela, Morales-Martinez, Mario, Jimenez-Hernandez, Elva, Huerta-Yepez, Sara

“…Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Current chemotherapy treatment regimens have improved survival rates to approximately…”
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Modulation of mitochondrial functions by the indirect antioxidant sulforaphane: A seemingly contradictory dual role and an integrative hypothesis by Negrette-Guzmán, Mario, Huerta-Yepez, Sara, Tapia, Edilia, Pedraza-Chaverri, José

“…The chemotherapeutic isothiocyanate sulforaphane (SFN) was early linked to anticarcinogenic and antiproliferative activities. Soon after, this compound,…”
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Bactofection of sequences encoding a Bax protein peptide chemosensitizes prostate cancer tumor cells by Marco Antonio Hernández-Luna, Ricardo Díaz de León-Ortega, Daniel Dimitri Hernández-Cueto, Ricardo Gaxiola-Centeno, Raúl Castro-Luna, Leonel Martínez-Cristóbal, Sara Huerta-Yépez, Rosendo Luria-Pérez

“…Background: Tumor cell resistance to chemotherapy agents is one of the main problems in the eradication of different neoplasias. One of the mechanisms of this…”
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Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming by Koutsioumpa, Marina, Hatziapostolou, Maria, Polytarchou, Christos, Tolosa, Ezequiel J, Almada, Luciana L, Mahurkar-Joshi, Swapna, Williams, Jennifer, Tirado-Rodriguez, Ana Belen, Huerta-Yepez, Sara, Karavias, Dimitrios, Kourea, Helen, Poultsides, George A, Struhl, Kevin, Dawson, David W, Donahue, Timothy R, Fernández-Zapico, Martín E, Iliopoulos, Dimitrios

“…Despite advances in the identification of epigenetic alterations in pancreatic cancer, their biological roles in the pathobiology of this dismal neoplasm…”
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Effect of IL-17A on the immune response to pulmonary tuberculosis induced by high- and low-virulence strains of Mycobacterium bovis by Rodríguez-Míguez, Yadira, Lozano-Ordaz, Vasti, Ortiz-Cabrera, Angel E, Barrios-Payan, Jorge, Mata-Espinosa, Dulce, Huerta-Yepez, Sara, Baay-Guzman, Guillermina, Hernández-Pando, Rogelio

“…Tuberculosis (TB) is an infectious, chronic, and progressive disease occurring globally. Human TB is caused mainly by Mycobacterium tuberculosis (M…”
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Omega-6 Polyunsaturated Fatty Acids Enhance Tumor Aggressiveness in Experimental Lung Cancer Model: Important Role of Oxylipins by Montecillo-Aguado, Mayra, Tirado-Rodriguez, Belen, Antonio-Andres, Gabriela, Morales-Martinez, Mario, Tong, Zhen, Yang, Jun, Hammock, Bruce D, Hernandez-Pando, Rogelio, Huerta-Yepez, Sara

“…Lung cancer is currently the leading cause of cancer death worldwide; it is often diagnosed at an advanced stage and bears poor prognosis. It has been shown…”
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Effect of melatonin on electrical impedance and biomarkers of damage in a gastric ischemia/reperfusion model by Peña-Mercado, Eduardo, Garcia-Lorenzana, Mario, Huerta-Yepez, Sara, Cruz-Ledesma, Anahis, Beltran-Vargas, Nohra E

“…The damage to the gastrointestinal mucosa induced by ischemia/reperfusion (I/R) is closely related to high mortality in critically ill patients, which is…”
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Differential mast cell numbers and characteristics in human tuberculosis pulmonary lesions by Garcia-Rodriguez, Karen Magdalena, Bini, Estela Isabel, Gamboa-Domínguez, Armando, Espitia-Pinzón, Clara Inés, Huerta-Yepez, Sara, Bulfone-Paus, Silvia, Hernández-Pando, Rogelio

“…Tuberculosis (TB) is still a major worldwide health threat and primarily a lung disease. The innate immune response against Mycobacterium tuberculosis ( Mtb )…”
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TGF-β: An Important Mediator of Allergic Disease and a Molecule with Dual Activity in Cancer Development by Huerta-Yepez, Sara, Segura-Medina, Patricia, Ortega, Enrique, Tirado-Rodriguez, Belen

“…The transforming growth factor-β (TGF-β) superfamily is a family of structurally related proteins that includes TGF-β, activins/inhibins, and bone morphogenic…”
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Sulforaphane induces differential modulation of mitochondrial biogenesis and dynamics in normal cells and tumor cells by Negrette-Guzmán, Mario, Huerta-Yepez, Sara, Vega, Mario I., León-Contreras, Juan Carlos, Hernández-Pando, Rogelio, Medina-Campos, Omar Noel, Rodríguez, Esteban, Tapia, Edilia, Pedraza-Chaverri, José

“…Antioxidant-based chemotherapy has been intensely debated. Herein, we show that sulforaphane (SFN) induced mitochondrial biogenesis followed by mitochondrial…”
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Bioelectric, tissue, and molecular characteristics of the gastric mucosa at different times of ischemia by Eduardo, Peña-Mercado, Mario, Garcia-Lorenzana, Carlos César, Patiño-Morales, Mayra, Montecillo-Aguado, Sara, Huerta-Yepez, E, Beltran Nohra

“…Gastrointestinal ischemia may be presented as a complication associated with late shock detection in patients in critical condition. Prolonged ischemia can…”
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Upregulated Nuclear Expression of Soluble Epoxide Hydrolase Predicts Poor Outcome in Breast Cancer Patients: Importance of the Digital Pathology Approach by Montecillo-Aguado, Mayra, Soca-Chafre, Giovanny, Antonio-Andres, Gabriela, Morales-Martinez, Mario, Tirado-Rodriguez, Belen, Rocha-Lopez, Angelica G, Hernandez-Cueto, Daniel, Sánchez-Ceja, Sandra G, Alcala-Mota-Velazco, Berenice, Gomez-Garcia, Anel, Gutiérrez-Castellanos, Sergio, Huerta-Yepez, Sara

“…Breast cancer (BC) is the most common cancer in women, with incidence rates increasing globally in recent years. Therefore, it is important to find new…”
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The Cysteine Protease Giardipain-1 from Giardia duodenalis Contributes to a Disruption of Intestinal Homeostasis by Quezada-Lázaro, Rodrigo, Vázquez-Cobix, Yessica, Fonseca-Liñán, Rocío, Nava, Porfirio, Hernández-Cueto, Daniel Dimitri, Cedillo-Peláez, Carlos, López-Vidal, Yolanda, Huerta-Yepez, Sara, Ortega-Pierres, M. Guadalupe

“…In giardiasis, diarrhoea, dehydration, malabsorption, weight loss and/or chronic inflammation are indicative of epithelial barrier dysfunction. However, the…”
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Chemotherapeutic drugs sensitize cancer cells to TRAIL-mediated apoptosis: up-regulation of DR5 and inhibition of Yin Yang 1 by Baritaki, Stavroula, Huerta-Yepez, Sara, Sakai, Toshiyuki, Spandidos, Demetrios A, Bonavida, Benjamin

“…Several chemotherapeutic drugs in combination with tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) result in reversal of resistance to…”
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