Search Results - "Huelgas, Gabriela"

C. elegans germline cell death, live by Huelgas Morales, Gabriela, Greenstein, David

“…DTC, distal tip cell. https://doi.org/10.1371/journal.pgen.1007425.g001 Raiders and colleagues used a combination of live imaging and an examination of fixed…”
Get full text

Control of oocyte meiotic maturation in C. elegans by Huelgas-Morales, Gabriela, Greenstein, David

“…In virtually all sexually reproducing animals, oocytes arrest in meiotic prophase and resume meiosis in a conserved biological process called meiotic…”
Get full text

Use of Novel Homochiral Thioureas Camphor Derived as Asymmetric Organocatalysts in the Stereoselective Formation of Glycosidic Bonds by López, Mildred, Huelgas, Gabriela, Sánchez, Mario, Armenta, Adalid, Mendoza, Angel, Lozada-Ramírez, José Daniel, Anaya de Parrodi, Cecilia

“…We synthesized six new camphor-derived homochiral thioureas - , from commercially available (1 )-(-)-camphorquinone. These new compounds - were evaluated as…”
Get full text

LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans by Tsukamoto, Tatsuya, Gearhart, Micah D, Spike, Caroline A, Huelgas-Morales, Gabriela, Mews, Makaela, Boag, Peter R, Beilharz, Traude H, Greenstein, David

“…An extended meiotic prophase is a hallmark of oogenesis. Hormonal signaling activates the CDK1/cyclin B kinase to promote oocyte meiotic maturation, which…”
Get full text

TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation by Guo, Qianjin, Cheng, Zi-Ming, Gonzalez-Cantú, Hector, Rotondi, Matthew, Huelgas-Morales, Gabriela, Ethiraj, Purushoth, Qiu, Zhijun, Lefkowitz, Jonathan, Song, Wan, Landry, Bethany N., Lopez, Hector, Estrada-Zuniga, Cynthia M., Goyal, Shivi, Khan, Mohammad Aasif, Walker, Timothy J., Wang, Exing, Li, Faqian, Ding, Yanli, Mulligan, Lois M., Aguiar, Ricardo C.T., Dahia, Patricia L.M.

“…The TMEM127 gene encodes a transmembrane protein of poorly known function that is mutated in pheochromocytomas, neural crest-derived tumors of adrenomedullary…”
Get full text

Synthesis and conformational analysis of novel tertiary amides derived from N-[(S)-α-phenylethyl]-1,3-imidazolidine by Santacruz-Juárez, Ericka, Höpfl, Herbert, Huelgas, Gabriela, Romero, Oscar, Castro, Alejandro, Parrodi, Cecilia Anaya de, Morales-Meza, Sharity, Sanchez, Mario

Get full text

The Stress Granule RNA-Binding Protein TIAR-1 Protects Female Germ Cells from Heat Shock in Caenorhabditis elegans by Huelgas-Morales, Gabriela, Silva-García, Carlos Giovanni, Salinas, Laura S, Greenstein, David, Navarro, Rosa E

“…In response to stressful conditions, eukaryotic cells launch an arsenal of regulatory programs to protect the proteome. One major protective response involves…”
Get full text

DPFF‐1 transcription factor deficiency causes the aberrant activation of MPK‐1 and meiotic defects in the Caenorhabditis elegans germline by Villanueva‐Chimal, Emmanuel, Salinas, Laura S., Fernández‐Cardenas, Laura P., Huelgas‐Morales, Gabriela, Cabrera‐Wrooman, Alejandro, Navarro, Rosa E.

“…Summary The d4 family of transcription factors consists of three members in mammals. DPF1/neuro‐d4 is expressed mainly in neurons and the peripheral nervous…”
Get full text

Combination of Phosphodiesterase 4 (PDE4) Inhibitor Roflumilast and R-CHOP As First-Line Therapy for High-Risk Diffuse Large B Cell Lymphoma Patients by Diaz Duque, Adolfo Enrique, Karnad, Anand, Butler, Matthew James, Bowhay-Carnes, Elizabeth, Michalek, Joel E, Huelgas, Gabriela, Aguiar, Ricardo

Get full text

Abstract 6891: Establishment and characterization of a panel of naïve and pretreated small cell lung cancer (SCLC) XPDX models by Morales, Gabriela Huelgas, Forofontov, Peter, Flores, Johnnie, Simonson, Alyssa, Diaz, Armando, Lund, Jim, Banos, Natalia, Papadopoulos, Kyriakos, Rasco, Drew, Patnaik, Amita, Abedi, Ali, Puente, Napoleon, Calvo, Emiliano, Moreno, Victor, Drengler, Ronald, Smith, Lon, Wick, Michael

“…Abstract SCLC is an aggressive cancer of neuroendocrine origin, accounting for approximately 15% of all lung cancer cases. While the incidence of SCLC in the…”
Get full text

Homochiral bifunctional L‐prolinamide‐ and L‐bis‐prolinamide‐catalyzed asymmetric aldol reactions performed in wet solvent‐free conditions by Huelgas, Gabriela, Somanathan, Ratnasamy, Hernández Pérez, Julio M., Rojas Cabrera, Haydee, Higuera Macías, Maximiliano, Domínguez‐Huerta, Alejandra, Sabala, Rocío, Anaya de Parrodi, Cecilia

“…In this study, the novel bifunctional homochiral thiourea‐L‐prolinamides 1–4, tertiary amino‐L‐prolinamide 5, and bis‐L‐prolinamides 6 and 7 were prepared from…”
Get full text

Homochiral l-prolinamido-sulfonamides and their use as organocatalysts in aldol reactions by Rojas Cabrera, Haydee, Huelgas, Gabriela, Hernández Pérez, Julio M., Walsh, Patrick J., Somanathan, Ratnasamy, Anaya de Parrodi, Cecilia

“…[Display omitted] The synthesis of new homochiral l-prolinamido-sulfonamides 1–7 from enantiomerically pure…”
Get full text

‘Syn-effect’ in the diastereoselective alkylation of 3-[(E)-α,β-unsaturated-γ-substituted]-N-acyloxazolidinones by Jiménez, Jacqueline, Ramírez, JuánCarlos, Huelgas, Gabriela, Meléndrez, Ruth, Cabrera-Vivas, Blanca M., Sansinenea, Estibaliz, Ortiz, Aurelio

“…Synthetic methods for the formation of alkenes usually produce the E-alkene because it is more stable. However, in isomerization reaction (double bond…”
Get full text

A Concise Stereoselective Synthesis of (R)‐2‐Benzylmorpholine and ML398 from (R)‐(−)‐2‐Phenylglycinol by Torres, Saúl, Velasco, Manuel, Gallegos‐Rojas, José Ángel, Bernès, Sylvain, Orea, María L., Terán, Joel L., Huelgas, Gabriela, Gómez‐Calvario, Víctor, Juárez, Jorge R.

“…We describe here an efficient stereoselective method for the preparation of (R)‐2‐benzylmorpholine and ML398. The present method features a high…”
Get full text

Oxazolidine Sulfur Ylides Derived from Phenylglycinol for the Specific and Highly Diastereoselective Synthesis of Aryl and Alkyl trans-Epoxyamides by Gordillo, Paola G., Aparicio, David M., Flores, Marcos, Mendoza, Angel, Orea, Laura, Juárez, Jorge R., Huelgas, Gabriela, Gnecco, Dino, Terán, Joel L.

“…Aryl and alkyl chiral oxazolidine sulfonium salts with cis and trans dispositions derived from (–)‐(R)‐2‐phenylglycinol were demonstrated to be good to…”
Get full text

New ligands and structural insights into the catalytic asymmetric addition of organozinc reagents to ketones by Huelgas, Gabriela, LaRochelle, Lynne K., Rivas, Lucrecia, Luchinina, Yekaterina, Toscano, Rubén A., Carroll, Patrick J., Walsh, Patrick J., Anaya de Parrodi, Cecilia

“…The catalytic asymmetric addition of alkyl groups to ketones has received considerable attention. Outlined herein is the synthesis of two new ligands based on…”
Get full text

Decreased mechanotransduction prevents nuclear collapse in a Caenorhabditis elegans laminopathy by Huelgas-Morales, Gabriela, Sanders, Mark, Mekonnen, Gemechu, Tsukamoto, Tatsuya, Greenstein, David

“…The function of the nucleus depends on the integrity of the nuclear lamina, an intermediate filament network associated with the linker of nucleoskeleton and…”
Get full text

Multiple Mechanisms Inactivate the LIN-41 RNA-Binding Protein To Ensure a Robust Oocyte-to-Embryo Transition in Caenorhabditis elegans by Spike, Caroline A, Huelgas-Morales, Gabriela, Tsukamoto, Tatsuya, Greenstein, David

“…In the nematode , the conserved LIN-41 RNA-binding protein is a translational repressor that coordinately controls oocyte growth and meiotic maturation. LIN-41…”
Get full text

New ligands and structural insights into the catalytic asymmetric addition of organozinc reagents to ketones: Tetrahedron Young Investigator award 2011. Useful Synthetic Methods: Innovative Developments and Applications. F. Dean Toste by HUELGAS, Gabriela, LAROCHELLE, Lynne K, RIVAS, Lucrecia, LUCHININA, Yekaterina, TOSCANO, Ruben A, CARROLL, Patrick J, WALSH, Patrick J, DE PARRODI, Cecilia Anaya

Get full text

Catalytic asymmetric hydrosilylation of acetophenone with new chiral thiourea ligands containing the ( S)-α-phenylethyl group by Santacruz, Ericka, Huelgas, Gabriela, Angulo, Sandra K., Mastranzo, Virginia M., Hernández-Ortega, Simón, Aviña, Judit A., Juaristi, Eusebio, Parrodi, Cecilia Anaya de, Walsh, Patrick J.

“…New chiral thioureas 1–8 containing 1,2-ethylendiamine or trans-1,2-diaminocyclohexane as the carbon skeleton, and containing an ( S)-α-phenylethyl group have…”
Get full text