Search Results - "Huebinger, Ryan M."

Study protocol for the Innovative Support for Patients with SARS-COV-2 Infections Registry (INSPIRE): A longitudinal study of the medium and long-term sequelae of SARS-CoV-2 infection by O'Laughlin, Kelli N, Thompson, Matthew, Hota, Bala, Gottlieb, Michael, Plumb, Ian D, Chang, Anna Marie, Wisk, Lauren E, Hall, Aron J, Wang, Ralph C, Spatz, Erica S, Stephens, Kari A, Huebinger, Ryan M, McDonald, Samuel A, Venkatesh, Arjun, Gentile, Nikki, Slovis, Benjamin H, Hill, Mandy, Saydah, Sharon, Idris, Ahamed H, Rodriguez, Robert, Krumholz, Harlan M, Elmore, Joann G, Weinstein, Robert A, Nichol, Graham

“…Reports on medium and long-term sequelae of SARS-CoV-2 infections largely lack quantification of incidence and relative risk. We describe the rationale and…”
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Mathematical model predicts anti-adhesion-antibiotic-debridement combination therapies can clear an antibiotic resistant infection by Roberts, Paul A, Huebinger, Ryan M, Keen, Emma, Krachler, Anne-Marie, Jabbari, Sara

“…As antimicrobial resistance increases, it is crucial to develop new treatment strategies to counter the emerging threat. In this paper, we consider combination…”
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Predictive modelling of a novel anti-adhesion therapy to combat bacterial colonisation of burn wounds by Roberts, Paul A, Huebinger, Ryan M, Keen, Emma, Krachler, Anne-Marie, Jabbari, Sara

“…As the development of new classes of antibiotics slows, bacterial resistance to existing antibiotics is becoming an increasing problem. A potential solution is…”
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Targeting bacterial adherence inhibits multidrug-resistant Pseudomonas aeruginosa infection following burn injury by Huebinger, Ryan M., Stones, Daniel H., de Souza Santos, Marcela, Carlson, Deborah L., Song, Juquan, Vaz, Diana Pereira, Keen, Emma, Wolf, Steven E., Orth, Kim, Krachler, Anne Marie

“…Classical antimicrobial drugs target proliferation and therefore place microbes under extreme selective pressure to evolve resistance. Alternative drugs that…”
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Survey-based Evaluation of Resident and Attending Financial Literacy by Huebinger, Ryan, Hussain, Rahat, Tupchong, Keegan, Walia, Shabana, Fairbrother, Hilary, Rogg, Jonathan

“…Introduction: Physician finances are linked to wellness and burnout. However, few physicians receive financial management education. We sought to determine the…”
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Branched-Chain Amino Acids Are Linked with Alzheimer's Disease-Related Pathology and Cognitive Deficits by Siddik, Md Abu Bakkar, Mullins, Caitlyn A, Kramer, Alyssa, Shah, Harsh, Gannaban, Ritchel B, Zabet-Moghaddam, Masoud, Huebinger, Ryan M, Hegde, Vijay K, MohanKumar, Sheba M J, MohanKumar, Puliyur S, Shin, Andrew C

“…Alzheimer's disease (AD) is an irreversible neurodegenerative disorder with a complex pathophysiology. Type 2 diabetes (T2D) is a strong risk factor for AD…”
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Variations of the lung microbiome and immune response in mechanically ventilated surgical patients by Huebinger, Ryan M, Smith, Ashley D, Zhang, Yan, Monson, Nancy L, Ireland, Sara J, Barber, Robert C, Kubasiak, John C, Minshall, Christian T, Minei, Joseph P, Wolf, Steven E, Allen, Michael S

“…Mechanically ventilated surgical patients have a variety of bacterial flora that are often undetectable by traditional culture methods. The source of infection…”
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Common Lung Microbiome Identified among Mechanically Ventilated Surgical Patients by Smith, Ashley D, Zhang, Yan, Barber, Robert C, Minshall, Christian T, Huebinger, Ryan M, Allen, Michael S

“…The examination of the pulmonary microbiome in patients with non-chronic disease states has not been extensively examined. Traditional culture based screening…”
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Can Genetic Analysis of Putative Blood Alzheimer's Disease Biomarkers Lead to Identification of Susceptibility Loci? by Barber, Robert C, Phillips, Nicole R, Tilson, Jeffrey L, Huebinger, Ryan M, Shewale, Shantanu J, Koenig, Jessica L, Mitchel, Jeffrey S, O'Bryant, Sid E, Waring, Stephen C, Diaz-Arrastia, Ramon, Chasse, Scott, Wilhelmsen, Kirk C

“…Although 24 Alzheimer's disease (AD) risk loci have been reliably identified, a large portion of the predicted heritability for AD remains unexplained. It is…”
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Adaptive lymphocyte profiles correlate to brain Aβ burden in patients with mild cognitive impairment by Stowe, Ann M, Ireland, Sara J, Ortega, Sterling B, Chen, Ding, Huebinger, Ryan M, Tarumi, Takashi, Harris, Thomas S, Cullum, C Munro, Rosenberg, Roger, Monson, Nancy L, Zhang, Rong

“…We previously found that subjects with amnestic mild cognitive impairment exhibit a pro-inflammatory immune profile in the cerebrospinal fluid similar to…”
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Ethnic and racial differences in self-reported symptoms, health status, activity level, and missed work at 3 and 6 months following SARS-CoV-2 infection by O'Laughlin, Kelli N, Klabbers, Robin E, Ebna Mannan, Imtiaz, Gentile, Nicole L, Geyer, Rachel E, Zheng, Zihan, Yu, Huihui, Li, Shu-Xia, Chan, Kwun C G, Spatz, Erica S, Wang, Ralph C, L'Hommedieu, Michelle, Weinstein, Robert A, Plumb, Ian D, Gottlieb, Michael, Huebinger, Ryan M, Hagen, Melissa, Elmore, Joann G, Hill, Mandy J, Kelly, Morgan, McDonald, Samuel, Rising, Kristin L, Rodriguez, Robert M, Venkatesh, Arjun, Idris, Ahamed H, Santangelo, Michelle, Koo, Katherine, Saydah, Sharon, Nichol, Graham, Stephens, Kari A

“…Data on ethnic and racial differences in symptoms and health-related impacts following SARS-CoV-2 infection are limited. We aimed to estimate the ethnic and…”
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Retrospective Study of Midazolam Protocol for Prehospital Behavioral Emergencies by Huebinger, Ryan M, Zaidi, Hashim Q, Tataris, Katie L, Weber, Joseph M, Pearlman, Kenneth S, Markul, Eddie, Stein-Spencer, Leslee, Richards, Christopher T

“…Agitated patients in the prehospital setting pose challenges for both patient care and emergency medical services (EMS) provider safety. Midazolam is…”
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Outcomes of end‐stage renal disease patients in the PROCESS trial by Huebinger, Ryan M., Walia, Shabana, Yealy, Donald M., Kellum, John A., Huang, David T., Wang, Henry E.

“…Objective Intravenous fluid administration is a main component of sepsis therapy, but physicians are cautious about giving fluids to end‐stage renal disease…”
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Clinical characteristics and course of out‐of‐hospital shock in a national emergency medical services cohort by George, Timothy P., Chan, Hei Kit, Crowe, Remle P., Jarvis, Jeffrey L., Jansen, Jan O., Huebinger, Ryan M., Wang, Henry E.

“…Background Shock from medical and traumatic conditions can result in organ injury and death. Limited data describe out‐of‐hospital treatment of shock. We…”
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Video laryngoscopy for out of hospital cardiac arrest by Huebinger, Ryan M., Stilgenbauer, Hutch, Jarvis, Jeff L., Ostermayer, Daniel G., Schulz, Kevin, Wang, Henry E.

“…Endotracheal intubation is an import component of out-of-hospital cardiac arrest (OHCA) resuscitation. In this analysis, we evaluate the association of video…”
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IL-10 Polymorphism Associated with Decreased Risk for Mortality After Burn Injury by Huebinger, Ryan M., Ph.D, Rivera-Chavez, Fernando, M.D, Chang, Ling-Yu, B.S, Liu, Ming-Mei, B.S, Minei, Joseph P., M.D, Purdue, Gary F., M.D, Hunt, John L., M.D, Arnoldo, Brett D., M.D, Barber, Robert C., Ph.D

“…Objective Evaluation of single nucleotide polymorphisms (SNPs) in the interleukin‑10 promoter (‑592 and ‑819) on risk for death after burn injury. Methods…”
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Three-Month Symptom Profiles Among Symptomatic Adults With Positive and Negative Severe Acute Respiratory Syndrome Coronavirus 2 Tests: A Prospective Cohort Study From the INSPIRE Group by Spatz, Erica S, Gottlieb, Michael, Wisk, Lauren E, Anderson, Jill, Chang, Anna Marie, Gentile, Nicole L, Hill, Mandy J, Huebinger, Ryan M, Idris, Ahamed H, Kinsman, Jeremiah, Koo, Katherine, Li, Shu-Xia, McDonald, Samuel, Plumb, Ian D, Rodriguez, Robert M, Saydah, Sharon, Slovis, Benjamin, Stephens, Kari A, Unger, Elizabeth R, Wang, Ralph C, Yu, Huihui, Hota, Bala, Elmore, Joann G, Weinstein, Robert A, Venkatesh, Arjun

“…Abstract Background Long-term symptoms following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are a major concern, yet their…”
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Association of Ketamine Dosing with Intubation and Other Adverse Events in Patients with Behavioral Emergencies by Sergot, Paulina B., Mead, Loren B., Jones, Elizabeth B., Crowe, Remle P., Huebinger, Ryan M.

“…Varying rates of complications have been reported for prehospital sedation with ketamine, and the relationship to dosing has not been studied on a large scale…”
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Burn Serum Stimulates Myoblast Cell Death Associated with IL-6-Induced Mitochondrial Fragmentation by Sehat, Alvand, Huebinger, Ryan M, Carlson, Deborah L, Zang, Qun S, Wolf, Steven E, Song, Juquan

“…Burn patients suffer muscle mass loss associated with hyperinflammation and hypercatabolism. The mitochondria are affected by this metabolic alteration…”
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Elevated CNS Inflammation in Patients with Preclinical Alzheimer's Disease by Monson, Nancy L, Ireland, Sara J, Ligocki, Ann J, Chen, Ding, Rounds, William H, Li, Min, Huebinger, Ryan M, Munro Cullum, C, Greenberg, Benjamin M, Stowe, Ann M, Zhang, Rong

“…Alzheimer's disease (AD) is a progressive, neurodegenerative disease that may involve inflammatory responses in the central nervous system (CNS). Our objective…”
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