Search Results - "Hudson, Robert H.E"

On the Necessity of Nucleobase Protection for 2‑Thiouracil for Fmoc-Based Pseudo-Complementary Peptide Nucleic Acid Oligomer Synthesis by Hudson, Robert H.E, Heidari, Ali, Martin-Chan, Timothy, Park, Gyeongsu, Wisner, James A

“…A selection of benzyl-based protecting groups for thiouracil (SU) for the synthesis of pseudo-complementary peptide nucleic acid (PNA) has been evaluated. The…”
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Supported organometallic palladium catalyst into mesoporous channels of magnetic MCM-41 nanoparticles for phosphine-free C C coupling reactions by Ghorbani-Choghamarani, Arash, Tahmasbi, Bahman, Hudson, Robert H.E., Heidari, Ali

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Boehmite@tryptophan‐Pd nanoparticles: A new catalyst for C–C bond formation by Ghorbani‐Choghamarani, Arash, Mohammadi, Masoud, Hudson, Robert H.E., Tamoradi, Taiebeh

“…A boehmite@tryptophan‐Pd nanoparticulate catalyst was prepared by a simple, fast and convenient route. The nanomaterial was characterized using various…”
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FSM-16/AEPC-SO3H: Synthesis, Characterization and Its Application for the Catalytic Preparation of 1,8-Dioxo-octahydroxanthene and Tetrahydrobenzo[b]pyran Derivatives by Hajjami, Maryam, Gholamian, Fatemeh, Hudson, Robert H. E., Sanati, Ali Mohammad

“…A new acidic mesoporous catalyst (FSM-16/AEPC-SO 3 H) was successfully synthesized and characterized by FT-IR, TGA, XRD, SEM, TEM, EDS and BET techniques. The…”
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The use of Sonogashira coupling for the synthesis of modified uracil peptide nucleic acid by Hudson, Robert H.E, Li, Ge, Tse, Joseph

“…Palladium-catalyzed Sonogashira coupling has been shown to be compatible with PNA monomers as illustrated by the reaction of 5-iodouracil peptide nucleic acid…”
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6‐phenylpyrrolocytosine as a fluorescent probe to examine nucleotide flipping catalyzed by a DNA repair protein by Kotandeniya, Delshanee, Rogers, Melanie S., Fernandez, Jenna, Kanugula, Sreenivas, Hudson, Robert H. E., Rodriguez, Freddys, Lipscomb, John D., Tretyakova, Natalia

“…Cellular exposure to tobacco‐specific nitrosamines causes formation of promutagenic O6‐[4‐oxo‐4‐(3‐pyridyl)but‐1‐yl]guanine (O6‐POB‐G) and O6‐methylguanine…”
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PNA Molecular Beacons Assembled by Post-Synthetic Click Chemistry Functionalization by Wang, Xiaoxiao, Hudson, Robert H. E.

“…To avoid the tedious synthesis of functionalized peptide nucleic acid (PNA) monomers for probe development, we proposed a simple approach to modify PNA…”
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Synthesis and photophysical evaluation of new fluorescent 7-arylethynyl-7-deazaadenosine analogs by Matarazzo, Augusto, Brow, Justin, Hudson, Robert H.E

“…Three new fluorescent 7-deaza-2′-deoxyadenosine analogs were synthesized via the Sonogashira cross-coupling reaction of 7-iodo-7-deaza-2′-deoxyadenosine with…”
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Tribute to J. Peter Guthrie, FCIC, FRSC 1942–2017 by Workentin, Mark S, Hudson, Robert H.E

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single-label phenylpyrrolocytidine provides a molecular beacon-like response reporting HIV-1 RT RNase H activity by Wahba, Alexander S, Esmaeili, Abbasali, Damha, Masad J, Hudson, Robert H.E

“…6-Phenylpyrrolocytidine (PhpC), a structurally conservative and highly fluorescent cytidine analog, was incorporated into oligoribonucleotides. The…”
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A sensitive PARACEST contrast agent for temperature MRI: Eu3+-DOTAM-glycine (Gly)-phenylalanine (Phe) by Li, Alex X., Wojciechowski, Filip, Suchy, Mojmir, Jones, Craig K., Hudson, Robert H.E., Menon, Ravi S., Bartha, Robert

“…Tissue temperature is a fundamental physiological parameter that can provide insight into pathological processes. The purpose of this study was to develop and…”
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Preliminary evaluation of PARACEST MRI agents for the detection of nitric oxide synthase by Suchý, Mojmír, Li, Alex X, Liu, Yin, Feng, Qingping, Bartha, Robert, Hudson, Robert H.E

“…Several paramagnetic chemical exchange saturation transfer magnetic resonance imaging (PARACEST MRI) agents for the potential detection of nitric oxide…”
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A novel positron emission tomography contrast agent targeting cathepsin d shows preferential in vivo retention in an Alzheimer’s disease mouse model by Snir, Jonatan A, Suchy, Mojmir, Bindseil, Geron A, Chronik, Blaine A, Hudson, Robert H.E, Pasternak, Stephen H, Bartha, Robert

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A novel positron emission tomography contrast agent targeting cathepsin d shows preferential in vivo retention in an Alzheimer’s disease mouse model by Snir, Jonatan A, Suchy, Mojmir, Bindseil, Geron A, Chronik, Blaine A, Hudson, Robert H.E, Pasternak, Stephen H, Bartha, Robert

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Dynamic optical imaging of a cleavable CPP-bound dual NIR fluorescent/MRI probe targeting cathepsin D by Snir, Jonatan, Suchy, Mojmir, Li, Alex X, Lawrence, Keith St, Hudson, Robert H.E, Pasternak, Stephen, Bartha, Robert

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A dual magnetic resonance imaging/fluorescent contrast agent for Cathepsin-D detection by Ta, Robert, Suchy, Mojmir, Tam, Joshua H K, Li, Alex X, Martinez-Santiesteban, Francisco S, Scholl, Timothy J, Hudson, Robert H E, Bartha, Robert, Pasternak, Stephen H

“…Currently there are no approved biomarkers for the pre-symptomatic diagnosis of Alzheimer's disease (AD). Cathepsin-D (Cat-D) is a lysosomal protease that is…”
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Analysis and purification of peptide nucleic acids by denaturing PAGE by Dodd, David W, Hudson, Robert H.E

“…A flexible and convenient protocol for the analysis and purification of peptide nucleic acid (PNA) oligomers and PNA-peptide chimeras by denaturing PAGE is…”
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Hydrophilic modifications in peptide nucleic acid Synthesis and properties of PNA possessing 5-hydroxymethyluracil and 5-hydroxymethylcytosine by Hudson, Robert HE, Liu, Yuhong, Wojciechowski, Filip

“…We have investigated the chemistry for the incorporation of C5-hydroxymethyl-uracil and -cytosine in peptide nucleic acid (PNA) and the subsequent effect of…”
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In-Vitro and In-Vivo Study of a Magnetic Resonance Imaging (MRI)/Fluorescent Contrast Agent for Detection in Alzheimer's Disease by Ta, Robert, Li, Alex X, Suchy, Mojmir, Hudson, Robert H.E, Pasternak, Stephen H, Bartha, Robert

“…Background: A new magnetic resonance imaging (MRI)/fluorescent contrast agent, DOTA-CAT, has been designed to detect a biological target. DOTA-CAT consists of…”
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In vitro cellular uptake of a magnetic resonance imaging (MRI)/fluorescent contrast agent for detection of Cathepsin-D activity in Alzheimer's disease by Ta, Robert M, Li, Alex X, Suchy, Mojmir, Hudson, Robert H.E, Pasternak, Stephen H, Bartha, Robert

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