Search Results - "Hudson, Richard A"

The burden of selected vaccine-preventable diseases on the secondary care health system in England: Results from a five-year administrative healthcare dataset by Rabe, Adrian Paul J., Costello, Paul, Were, John J., Farrer, Archie, Hudson, Richard D.A.

“…•Resurgence of VPDs has been observed in England. The number of NHS 2ndry care episodes relating to 6 VPDs is reported here.•We show that these VPDs are…”
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Total Synthesis and Selective Activity of a New Class of Conformationally Restrained Epothilones by Alhamadsheh, Mamoun M., Gupta, Shuchi, Hudson, Richard A., Perera, Lalith, Tillekeratne, L. M. Viranga

“…Stereoselective total syntheses of two novel conformationally restrained epothilone analogues are described. Evans asymmetric alkylation, Brown allylation, and…”
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Electrochemical and Electrocatalytic Properties of Imidazole Analogues of the Redox Cofactor Pyrroloquinoline Quinone by Lumibao, Claudine Y., Tillekeratne, L. M. Viranga, Kirchhoff, Jon R., Fouchard, David M. D., Hudson, Richard A.

“…The electrochemical and electrocatalytic properties of two synthetic imidazole analogues of the redox cofactor pyrroloquinoline quinone (PQQ) were evaluated…”
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A Real-World Data Study on the Healthcare Resource Use for Uncontrolled Moderate-to-Severe Atopic Dermatitis in Secondary Care in the United Kingdom Prior to the Introduction of Biologic Treatment by Hudson, Richard D A, Ameen, Mahreen, George, Susannah M C, Harwood, Catherine A, Weller, Richard B, Lear, John T, Rout, Rajesh, Surendranathan, Thishi, Petrovic, Milos, Bewley, Anthony P

“…Whilst there is international evidence around the high healthcare resource utilization (HRU) associated with atopic dermatitis (AD), there is a lack of…”
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A rapid method for the purification of methanol dehydrogenase from Methylobacterium extorquens by Liu, Qinfeng, Kirchhoff, Jon R., Faehnle, Christopher R., Viola, Ronald E., Hudson, Richard A.

“…Methanol dehydrogenase (MDH) is a water soluble quinoprotein that catalyzes the oxidation of methanol as an important carbon source in methylotrophic bacteria…”
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Respiratory Syncytial Virus Hospital Admission Rates and Patients' Characteristics Before the Age of 2 Years in England, 2015-2019 by Fonseca, Maria João, Hagenaars, Saskia, Bangert, Mathieu, Flach, Clare, Hudson, Richard D A

“…A granular understanding of respiratory syncytial virus (RSV) burden in England is needed to prepare for new RSV prevention strategies. We estimated the rates…”
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English Grammar by Hudson, Richard

“…English Grammar: * helps users to understand grammatical concepts * encourages the reader to practise applying newly discovered concepts to everyday texts *…”
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Differential Inhibition of polymerase and Strand-Transfer Activities of HIV-1 Reverse Transcriptase by Tillekeratne, L.M.Viranga, Sherette, Angela, Fulmer, Jennifer A, Hupe, Lynn, Hupe, Donald, Gabbara, Sam, Peliska, James A, Hudson, Richard A

“…A new class of inhibitors of HIV-1 reverse transcriptase obtained by the systematic structural simplification of epicatechin and epigallocatechin gallates are…”
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Electrochemical detection of acetylcholine and choline: application to the quantitative nonradiochemical evaluation of choline transport by Barkhimer, Tatyana V, Kirchhoff, Jon R, Hudson, Richard A, Messer Jr, William S, Viranga Tillekeratne, L. M

“…The development of analytical methods for determining the cholinergic biomarkers acetylcholine (ACh) and choline (Ch) is important for assessing their role in…”
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Reductive Monoalkylation of Aromatic and Aliphatic Nitro Compounds and the Corresponding Amines with Nitriles by Nacario, Ruel, Kotakonda, Shailaja, Fouchard, David M. D., Tillekeratne, L. M. Viranga, Hudson, Richard A.

“…A simple, selective, rapid, and efficient procedure for the synthesis of secondary amines from the reductive alkylation of either aliphatic or aromatic nitro…”
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Apoptotic activities in closely related styryllactone stereoisomers toward human tumor cell lines: Investigation of synergism of styryllactone-induced apoptosis with TRAIL by Gupta, Shuchi, Poeppelman, Lee, Hinman, Channing. L., Bretz, James, Hudson, Richard A., Tillekeratne, L.M. Viranga

“…A comparative study of the apoptotic activities of a related group of styryllactones and the potential of one of them, (−)-altholactone, to act synergistically…”
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Design, Total Synthesis, and Evaluation of Novel Open-Chain Epothilone Analogues by Alhamadsheh, Mamoun M, Hudson, Richard A, Viranga Tillekeratne, L. M

“…The design, total synthesis, and biological evaluation of two open-chain analogues of epothilone incorporating the critical C1−C8 fragment and the aromatic…”
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Enhanced Measurement Stability and Selectivity for Choline and Acetylcholine by Capillary Electrophoresis with Electrochemical Detection at a Covalently Linked Enzyme-Modified Electrode by Inoue, Takayo, Kirchhoff, Jon R, Hudson, Richard A

“…Enzyme-modified microelectrodes were developed for the indirect amperometric detection of acetylcholine and choline following separation by capillary…”
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Inhibition of choline transport by redox-active cholinomimetic bis-catechol reagents by Cai, Shuang, Mukherjee, Jhindan, Tillekeratne, L.M. Viranga, Hudson, Richard A., Kirchhoff, Jon R.

“…Two symmetrical bis-catechol substituted hexamethonium and decamethonium analogues were found to inhibit high-affinity choline transport in mouse brain…”
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Effects of Antioxidants Coenzyme Q10 and Lipoic Acid on Interleukin-1β-Mediated Inhibition of Glucose-Stimulated Insulin Release from Cultured Mouse Pancreatic Islets by Schroeder, Michelle M., Belloto, Robert J., Hudson, Richard A., McInerney, Marcia F.

“…During the development of the autoimmune disease, insulin-dependent diabetes mellitus (IDDM) islet cell death is thought to be mediated in part by oxygen and…”
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Classification of the mode of inhibition of high-affinity choline uptake using capillary electrophoresis with electrochemical detection at an enzyme-modified microelectrode by Barkhimer, Tatyana V., Kirchhoff, Jon R., Hudson, Richard A., Messer, William S.

“…A nonradiochemical in vitro assay using capillary electrophoresis with electrochemical detection at an enzyme-modified microelectrode has been developed to…”
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Inhibition and inactivation of presynaptic cholinergic markers using redox-reactive choline analogs by Patel, Phenil J, Messer, William S, Hudson, Richard A

“…Inhibition and inactivation of two presynaptic cholinergic "markers", choline acetyltransferase and high affinity choline transporter, has been investigated…”
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Synthesis of Imidazolo Analogues of the Oxidation−Reduction Cofactor Pyrroloquinoline Quinone (PQQ) by Fouchard, David M. D, Tillekeratne, L. M. V, Hudson, Richard A

“…Parallel syntheses of 2-hydro-, 2-methyl-, and 2-methoxycarbonylimidazo-7,9-dimethoxycarbonyl analogues of the oxidation−reduction cofactor pyrroloquinoline…”
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Potent isothiocyanate inhibitors of carbonic anhydrase: synthesis and evaluation by Khobzaoui, Moussa, Tillekeratne, L.M.Viranga, Hudson, Richard A

“…The reversible hydration of carbon dioxide by carbonic anhydrase (CA) regulates pH and carbon dioxide concentrations in diverse biological systems. Potent…”
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Internal standard method for the measurement of choline and acetylcholine by capillary electrophoresis with electrochemical detection by Wise, Dana D, Barkhimer, Tatyana V, Brault, Pierre-Alexandre, Kirchhoff, Jon R, Messer, William S, Hudson, Richard A

“…An internal standard method has been developed for the determination of the neurotransmitter acetylcholine and/or its metabolic precursor choline. This…”
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