Search Results - "Hudson, Quanah J."
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The Role of Long Non-Coding RNAs in Endometriosis
Published in International journal of molecular sciences (22-10-2021)“…Endometriosis is a chronic gynecological disorder affecting the quality of life and fertility of many women around the world. Heterogeneous and non-specific…”
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The Airn lncRNA does not require any DNA elements within its locus to silence distant imprinted genes
Published in PLoS genetics (01-07-2019)“…Long non-coding (lnc) RNAs are numerous and found throughout the mammalian genome, and many are thought to be involved in the regulation of gene expression…”
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Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression
Published in eLife (14-08-2017)“…To determine the dynamics of allelic-specific expression during mouse development, we analyzed RNA-seq data from 23 F1 tissues from different developmental…”
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LINC01133 Inhibits Invasion and Promotes Proliferation in an Endometriosis Epithelial Cell Line
Published in International journal of molecular sciences (04-08-2021)“…Endometriosis is a common gynecological disorder characterized by ectopic growth of endometrium outside the uterus and is associated with chronic pain and…”
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Mechanisms of long range silencing by imprinted macro non-coding RNAs
Published in Current opinion in genetics & development (01-06-2012)“…Non-coding (nc) RNA silencing of imprinted genes in extra-embryonic tissues provides a good model for understanding an underexamined aspect of gene regulation…”
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Hsa-mir-135a Shows Potential as A Putative Diagnostic Biomarker in Saliva and Plasma for Endometriosis
Published in Biomolecules (Basel, Switzerland) (19-08-2022)“…Endometriosis is a chronic disease characterized by the implantation and proliferation of endometrial tissue outside of the uterine cavity. The nonspecific…”
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Correction: The Airn lncRNA does not require any DNA elements within its locus to silence distant imprinted genes
Published in PLoS genetics (21-10-2020)“…[This corrects the article DOI: 10.1371/journal.pgen.1008268.]…”
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The rs2046210 Polymorphism Is Associated with Endometriosis Risk and Elevated Estrogen Receptor 1 Expression in the Eutopic Endometrium of Women with the Disease
Published in Biomedicines (25-07-2024)“…In this focused genetic case-control study, we analyzed two functional single-nucleotide variants (SNVs) associated with breast cancer risk (rs2046210,…”
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Aromatase inhibition reduces expression of FOXL2 in the embryonic chicken ovary
Published in Developmental dynamics (01-07-2005)“…P450‐aromatase is the terminal estrogen‐synthesizing enzyme and a key gene in avian sex determination. Aromatase is expressed specifically in female gonads,…”
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New Candidate Genes Identified for Controlling Mouse Gonadal Sex Determination and the Early Stages of Granulosa and Sertoli Cell Differentiation
Published in Biology of reproduction (01-02-2010)“…Mammalian gonadal sex-determining (GSD) genes are expressed in a unique population of somatic cells that differentiate into granulosa cells in XX gonads or…”
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Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo
Published in Developmental biology (15-05-2011)“…A subset of imprinted genes in the mouse have been reported to show imprinted expression that is restricted to the placenta, a short-lived extra-embryonic…”
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Challenges in uncovering non-invasive biomarkers of endometriosis
Published in Experimental Biology and Medicine (01-03-2020)“…Endometriosis affects up to 10% of women of childbearing age, causing symptoms that can include chronic pelvic pain and reduced fertility. The symptoms are not…”
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A downstream CpG island controls transcript initiation and elongation and the methylation state of the imprinted Airn macro ncRNA promoter
Published in PLoS genetics (01-03-2012)“…A CpG island (CGI) lies at the 5' end of the Airn macro non-protein-coding (nc) RNA that represses the flanking Igf2r promoter in cis on paternally inherited…”
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Airn Transcriptional Overlap, But Not Its lncRNA Products, Induces Imprinted Igf2r Silencing
Published in Science (American Association for the Advancement of Science) (14-12-2012)“…Mammalian imprinted genes often cluster with long noncoding (lnc) RNAs. Three lncRNAs that induce parental-specific silencing show hallmarks indicating that…”
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Inducible uniparental chromosome disomy to probe genomic imprinting at single-cell level in brain and beyond
Published in Neurochemistry international (01-05-2021)“…Genomic imprinting is an epigenetic mechanism that results in parental allele-specific expression of ~1% of all genes in mouse and human. Imprinted genes are…”
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DIRAS3 regulates autophagy in an endometriosis epithelial cell line
Published in Reproductive biomedicine online (01-10-2023)“…What is the role of DIRAS3 in endometriosis pathogenesis? Prospective patient cohort study combined with experiments in the 12Z human endometriosis epithelial…”
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New Candidate Genes Identified for Controlling Mouse Gonadal Sex Determination and the Early Stages of Granulosa and Sertoli Cell Differentiation1
Published in Biology of reproduction (01-02-2010)“…Mammalian gonadal sex-determining (GSD) genes are expressed in a unique population of somatic cells that differentiate into granulosa cells in XX gonads or…”
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Endometriosis Patients Show an Increased M2 Response in the Peritoneal CD14 +low /CD68 +low Macrophage Subpopulation Coupled with an Increase in the T-helper 2 and T-regulatory Cells
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-10-2020)“…Endometriosis is a chronic inflammatory disease associated with an impaired immune response at the site of lesion implantation. The ability of macrophages to…”
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Expression and evolutionary conservation of the tescalcin gene during development
Published in Gene Expression Patterns (01-06-2009)“…The tescalcin gene ( Tesc) encodes an EF-hand calcium-binding protein that interacts with the sodium/hydrogen exchanger, NHE1. Previous studies indicated that…”
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Allelome.PRO, a pipeline to define allele-specific genomic features from high-throughput sequencing data
Published in Nucleic acids research (02-12-2015)“…Detecting allelic biases from high-throughput sequencing data requires an approach that maximises sensitivity while minimizing false positives. Here, we…”
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