Search Results - "Hudson, Jason S"
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Stability of the Na+ Form of the Human Telomeric G‑Quadruplex: Role of Adenines in Stabilizing G‑Quadruplex Structure
Published in ACS omega (31-01-2018)“…G-quadruplexes are higher order DNA structures that play significant roles in gene transcription and telomeric maintenance. The formation and stability of the…”
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Implementation of the first comprehensive state oral fluid drug testing program for roadside screening and laboratory testing in DUID cases—A 5-year review
Published in Journal of analytical toxicology (01-11-2023)“…Abstract Oral fluid (OF) is a valuable specimen for driving under the influence of drugs (DUID) applications. This study demonstrates the implementation of the…”
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Recognition and Binding of Human Telomeric G‑Quadruplex DNA by Unfolding Protein 1
Published in Biochemistry (Easton) (27-05-2014)“…The specific recognition by proteins of G-quadruplex structures provides evidence of a functional role for in vivo G-quadruplex structures. As previously…”
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Buprenorphine-Related Deaths in North Carolina from 2010 to 2018
Published in Journal of analytical toxicology (01-10-2021)“…Abstract Buprenorphine (BUP) is a commonly prescribed medication for the treatment of opioid use disorder (OUD). As prescriptions increase in North Carolina,…”
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Melatonin Supplementation in Undetermined Pediatric Deaths
Published in Journal of analytical toxicology (14-10-2022)“…Since 2015, the North Carolina Office of the Chief Medical Examiner has investigated seven deaths of infants and toddlers, ages 2 months to 3 years, with…”
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Death from Poppy Tea Consumption
Published in Journal of analytical toxicology (12-10-2020)“…Abstract The historical practice of brewing poppy tea for its opioid-like effects is reoccurring with modern-day substance users. We present four postmortem…”
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Pediatric opioid fatalities: What can we learn for prevention?
Published in Journal of forensic sciences (01-07-2021)“…The aim of this study was to highlight 19 cases investigated by the North Carolina Office of the Chief Medical Examiner over the last 12 years involving…”
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Interactions of Actinomycin D with Human Telomeric G-Quadruplex DNA
Published in Biochemistry (Easton) (02-06-2009)“…The G-quadruplex structural motif of DNA has emerged as a novel and exciting target for anticancer drug discovery. The human telomeric G-quadruplex consists of…”
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Structure and lipid interactions of an anti-inflammatory and anti-atherogenic 10-residue class G⁎ apolipoprotein J peptide using solution NMR
Published in Biochimica et biophysica acta (01-01-2011)“…The surprising observation that a 10-residue class G⁎ peptide from apolipoprotein J, [113–122]apoJ, possesses anti-inflammatory and anti-atherogenic properties…”
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