Search Results - "Hudoklin, Samo"
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Automatic segmentation of mitochondria and endolysosomes in volumetric electron microscopy data
Published in Computers in biology and medicine (01-04-2020)“…Automatic segmentation of intracellular compartments is a powerful technique, which provides quantitative data about presence, spatial distribution, structure…”
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Analysis of miR-9-5p, miR-124-3p, miR-21-5p, miR-138-5p, and miR-1-3p in Glioblastoma Cell Lines and Extracellular Vesicles
Published in International journal of molecular sciences (11-11-2020)“…Glioblastoma (GBM), the most common primary brain tumor, is a complex and extremely aggressive disease. Despite recent advances in molecular biology, there is…”
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Formation and maintenance of blood–urine barrier in urothelium
Published in Protoplasma (01-10-2010)“…Blood–urine barrier, which is formed during differentiation of superficial urothelial cells, is the tightest and most impermeable barrier in the body. In the…”
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Adipose-Derived Stem Cells Respond to Increased Osmolarities
Published in PloS one (05-10-2016)“…Cell therapies present a feasible option for the treatment of degenerated cartilaginous and intervertebral disc (IVD) tissues. Microenvironments of these…”
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Olanzapine decreased osteocyte maturation and Wnt/β-catenin signaling during loading of the alveolar bone in rats
Published in Biomolecules & biomedicine (01-02-2023)“…Several studies indicate the influence of olanzapine on bone metabolism; however, the results are contradictory. We evaluated the effects of olanzapine on the…”
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Extracellular Vesicles Derived Human-miRNAs Modulate the Immune System in Type 1 Diabetes
Published in Frontiers in cell and developmental biology (31-03-2020)“…Extracellular vesicles with their molecular cargo can modulate target cell response and may affect the pathogenesis of diseases. The extracellular vesicles…”
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Electron tomography of fusiform vesicles and their organization in urothelial cells
Published in PloS one (12-03-2012)“…The formation of fusiform vesicles (FVs) is one of the most distinctive features in the urothelium of the urinary bladder. FVs represent compartments for…”
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Urothelial plaque formation in post-Golgi compartments
Published in PloS one (24-08-2011)“…Urothelial plaques are specialized membrane domains in urothelial superficial (umbrella) cells, composed of highly ordered uroplakin particles. We investigated…”
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Raziskovalni modeli raka sečnega mehurja za izboljšanje diagnostike in zdravljenja
Published in Zdravniški vestnik (Ljubljana, Slovenia : 1992) (13-07-2020)“…Rak sečnega mehurja je ena najpogostejših rakavih bolezni pri moških in ima visoko stopnjo ponovljivosti, zaradi česar predstavlja velik ekonomski in socialni…”
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Polyelectrolyte–surfactant–complex nanoparticles as a delivery platform for poorly soluble drugs: A case study of ibuprofen loaded cetylpyridinium-alginate system
Published in International journal of pharmaceutics (30-04-2020)“…[Display omitted] Previously, we reported on the surfactant cetylpyridinium chloride (CPC) as a crosslinker of alginate for the formation of stable…”
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The Golgi complex: An organelle that determines urothelial cell biology in health and disease
Published in Histochemistry and cell biology (01-09-2022)“…The Golgi complex undergoes considerable structural remodeling during differentiation of urothelial cells in vivo and in vitro. It is known that in a healthy…”
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Encapsulation of doxorubicin prodrug in heat-triggered liposomes overcomes off-target activation for advanced prostate cancer therapy
Published in Acta biomaterialia (01-03-2022)“…L-377,202 prodrug consists of doxorubicin (Dox) conjugated to a prostate-specific antigen (PSA) peptide substrate that can be cleaved by enzymatically active…”
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Automatic segmentation and reconstruction of intracellular compartments in volumetric electron microscopy data
Published in Computer methods and programs in biomedicine (01-08-2022)“…BACKGROUND AND OBJECTIVESIn recent years, electron microscopy is enabling the acquisition of volumetric data with resolving power to directly observe the…”
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Increased endocytosis of magnetic nanoparticles into cancerous urothelial cells versus normal urothelial cells
Published in Histochemistry and cell biology (2018)“…The blood–urine barrier is the tightest and most impermeable barrier in the body and as such represents a problem for intravesical drug delivery applications…”
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Biocompatibility Parameters with Standard and Increased Dose of Citrate in Hemodialysis—A Randomized Trial
Published in Journal of clinical medicine (04-07-2021)“…Background: The dose of citrate needed in regional citrate anticoagulation (RCA) to achieve optimal biocompatibility is unknown. We performed a randomized…”
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PD1 blockade potentiates the therapeutic efficacy of photothermally-activated and MRI-guided low temperature-sensitive magnetoliposomes
Published in Journal of controlled release (10-04-2021)“…This study investigates the effect of PD1 blockade on the therapeutic efficacy of novel doxorubicin-loaded temperature-sensitive liposomes. Herein, we report…”
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Intracellular Activation of a Prostate Specific Antigen-Cleavable Doxorubicin Prodrug: A Key Feature Toward Prodrug-Nanomedicine Design
Published in Molecular pharmaceutics (01-04-2019)“…L-377,202 prodrug (Dox-PSA) was in phase I clinical trials for patients with metastatic castration-resistant prostate cancer (mCRPC). It consists of…”
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