Search Results - "Hudgins, Lisa C."

Chylomicronemia from GPIHBP1 autoantibodies by Miyashita, Kazuya, Lutz, Jens, Hudgins, Lisa C., Toib, Dana, Ashraf, Ambika P., Song, Wenxin, Murakami, Masami, Nakajima, Katsuyuki, Ploug, Michael, Fong, Loren G., Young, Stephen G., Beigneux, Anne P.

“…Some cases of chylomicronemia are caused by autoantibodies against glycosylphosphatidylinositol-anchored HDL binding protein 1 (GPIHBP1), an endothelial cell…”
Get full text

A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism by Fisher, ffolliott M, Kim, MiSung, Doridot, Ludivine, Cunniff, Jeremy C, Parker, Thomas S, Levine, Daniel M, Hellerstein, Marc K, Hudgins, Lisa C, Maratos-Flier, Eleftheria, Herman, Mark A

“…Abstract Objective Increased fructose consumption is a contributor to the burgeoning epidemic of non-alcoholic fatty liver disease (NAFLD). Recent evidence…”
Get full text

A Dual Sugar Challenge Test for Lipogenic Sensitivity to Dietary Fructose by Hudgins, Lisa C, Parker, Thomas S, Levine, Daniel M, Hellerstein, Marc K

“…An oral challenge of glucose and fructose gives a robust lipogenic response as measured from the increase in VLDL triglyceride palmitate over 4 hours. Context:…”
Get full text

Rationale and design of the familial hypercholesterolemia foundation CAscade SCreening for Awareness and DEtection of Familial Hypercholesterolemia registry by O’Brien, Emily C., PhD, Roe, Matthew T., MD, MHS, Fraulo, Elizabeth S., BSN, Peterson, Eric D., MD, MPH, Ballantyne, Christie M., MD, Genest, Jacques, MD, Gidding, Samuel S., MD, Hammond, Emma, BSc, PhD, Hemphill, Linda C., MD, Hudgins, Lisa C., MD, Kindt, Iris, MD, MPH, Moriarty, Patrick M., MD, Ross, Joyce, MSN, CRNP, Underberg, James A., MD, Watson, Karol, MD, Pickhardt, Dave, MBA, Rader, Daniel J., MD, Wilemon, Katherine, BS, Knowles, Joshua W., MD, PhD

“…Background Familial hypercholesterolemia (FH) is a hereditary condition caused by various genetic mutations that lead to significantly elevated low-density…”
Get full text

Role for Stearoyl-CoA Desaturase-1 in Leptin-Mediated Weight Loss by Cohen, Paul, Miyazaki, Makoto, Socci, Nicholas D., Hagge-Greenberg, Aaron, Liedtke, Wolfgang, Soukas, Alexander A., Sharma, Ratnendra, Hudgins, Lisa C., Ntambi, James M., Friedman, Jeffrey M.

“…Leptin elicits a metabolic response that cannot be explained by its anorectic effects alone. To examine the mechanism underlying leptin's metabolic actions, we…”
Get full text

Long-Term Safety and Efficacy of Low-Density Lipoprotein Apheresis in Childhood for Homozygous Familial Hypercholesterolemia by Hudgins, Lisa C., MD, Kleinman, Bryan, BS, Scheuer, Abby, FNP, White, Sharon, RN, Gordon, Bruce R., MD

“…Untreated pediatric patients with homozygous familial hypercholesterolemia usually have myocardial infarctions, heart failure, or death by the teenage years…”
Get full text

LpA-II:B:C:D:E: a new immunochemically-defined acute phase lipoprotein in humans by Bagdade, John D, Jilma, Bernd, Hudgins, Lisa C, Alaupovic, Petar, McCurdy, Carrie E

“…Previous studies of lipoproteins in patients with sepsis have been performed on density fractions isolated by conventional ultracentrifugation that are…”
Get full text

2023 Update on European Atherosclerosis Society Consensus Statement on Homozygous Familial Hypercholesterolaemia: new treatments and clinical guidance by Cuchel, Marina, Raal, Frederick J, Hegele, Robert A, Al-Rasadi, Khalid, Arca, Marcello, Averna, Maurizio, Bruckert, Eric, Freiberger, Tomas, Gaudet, Daniel, Harada-Shiba, Mariko, Hudgins, Lisa C, Kayikcioglu, Meral, Masana, Luis, Parhofer, Klaus G, Roeters van Lennep, Jeanine E, Santos, Raul D, Stroes, Erik S G, Watts, Gerald F, Wiegman, Albert, Stock, Jane K, Tokgözoğlu, Lale S, Catapano, Alberico L, Ray, Kausik K

“…Graphical Abstract Graphical Abstract Homozygous familial hypercholesterolaemia is a rare autosomal semi-dominant disease affecting males and females equally,…”
Get full text

Atherosclerosis in Survivors of Kawasaki Disease by Gupta-Malhotra, Monesha, MBBS, Gruber, Dorota, MS, GC, Abraham, Seena S., MBBS, Roman, Mary J., MD, Zabriskie, John B., MD, Hudgins, Lisa C., MD, Flynn, Patrick A., MD, Levine, Daniel M., MD, Okorie, Uzoma, MD, Baday, Aline, MS, Schiller, Myles S., MD, Maturi, Janet, MS, RD, Meehan, Diane, MS, RD, Dyme, Joshua, MD, Parker, Thomas S., MD, Wittkowski, Knut M., PhD, ScD, Gersony, Welton M., MD, Cooper, Rubin S., MD

“…Objectives To test the hypothesis that long-term survivors of low-risk Kawasaki disease (KD) have ongoing vascular inflammation and dysfunction and a higher…”
Get full text

A single intravenous dose of endotoxin rapidly alters serum lipoproteins and lipid transfer proteins in normal volunteers by Hudgins, Lisa C., Parker, Thomas S., Levine, Daniel M., Gordon, Bruce R., Saal, Stuart D., Jiang, Xian-cheng, Seidman, Cindy E., Tremaroli, Jolanta D., Lai, Julie, Rubin, Albert L.

“…Endotoxemia is associated with rapid and marked declines in serum levels of LDL and HDL by unknown mechanisms. Six normal volunteers received a single, small…”
Get full text

Relationship between carbohydrate-induced hypertriglyceridemia and fatty acid synthesis in lean and obese subjects by Hudgins, L.C, Hellerstein, M.K, Seidman, C.E, Neese, R.A, Tremaroli, J.D, Hirsch, J

“…We previously reported that a eucaloric, low fat, liquid formula diet enriched in simple carbohydrate markedly increased the synthesis of fatty acids in lean…”
Get full text

Lipoprotein Apheresis: Utility, Outcomes, and Implementation in Clinical Practice: A Scientific Statement From the American Heart Association by Gianos, Eugenia, Duell, P Barton, Toth, Peter P, Moriarty, Patrick M, Thompson, Gilbert R, Brinton, Eliot A, Hudgins, Lisa C, Nametka, Mary, Byrne, Kathleen H, Raghuveer, Geetha, Nedungadi, Prashant, Sperling, Laurence S

“…Despite the availability of multiple classes of lipoprotein-lowering medications, some high-risk patients have persistent hypercholesterolemia and may require…”
Get full text

Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States by deGoma, Emil M, Ahmad, Zahid S, O'Brien, Emily C, Kindt, Iris, Shrader, Peter, Newman, Connie B, Pokharel, Yashashwi, Baum, Seth J, Hemphill, Linda C, Hudgins, Lisa C, Ahmed, Catherine D, Gidding, Samuel S, Duffy, Danielle, Neal, William, Wilemon, Katherine, Roe, Matthew T, Rader, Daniel J, Ballantyne, Christie M, Linton, MacRae F, Duell, PBarton, Shapiro, Michael D, Moriarty, Patrick M, Knowles, Joshua W

“…Background-Cardiovascular disease burden and treatment patterns among patients with familial hypercholesterolemia (FH) in the United States remain poorly…”
Get full text

Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry by deGoma, Emil M, Ahmad, Zahid S, O’Brien, Emily C, Kindt, Iris, Shrader, Peter, Newman, Connie B, Pokharel, Yashashwi, Baum, Seth J, Hemphill, Linda C, Hudgins, Lisa C, Ahmed, Catherine D, Gidding, Samuel S, Duffy, Danielle, Neal, William, Wilemon, Katherine, Roe, Matthew T, Rader, Daniel J, Ballantyne, Christie M, Linton, MacRae F, Duell, P Barton, Shapiro, Michael D, Moriarty, Patrick M, Knowles, Joshua W

“…BACKGROUND—Cardiovascular disease burden and treatment patterns among patients with familial hypercholesterolemia (FH) in the United States remain poorly…”
Get full text

Clinical practice recommendations on lipoprotein apheresis for children with homozygous familial hypercholesterolaemia: An expert consensus statement from ERKNet and ESPN by Reijman, M. Doortje, Kusters, D. Meeike, Groothoff, Jaap W., Arbeiter, Klaus, Dann, Eldad J., de Boer, Lotte M., de Ferranti, Sarah D., Gallo, Antonio, Greber-Platzer, Susanne, Hartz, Jacob, Hudgins, Lisa C., Ibarretxe, Daiana, Kayikcioglu, Meral, Klingel, Reinhard, Kolovou, Genovefa D., Oh, Jun, Planken, R. Nils, Stefanutti, Claudia, Taylan, Christina, Wiegman, Albert, Schmitt, Claus Peter

“…Homozygous familial hypercholesterolaemia is a life-threatening genetic condition, which causes extremely elevated LDL-C levels and atherosclerotic…”
Get full text

Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase by Weinstock, P.H, Levak-Frank, S, Hudgins, L.C, Radner, H, Friedman, J.M, Zechner, R, Breslow, J.L

“…Lipoprotein lipase (LPL) is the rate-limiting enzyme for the import of triglyceride-derived fatty acids by muscle, for utilization, and adipose tissue (AT),…”
Get full text

Children with Heterozygous Familial Hypercholesterolemia in the United States: Data from the Cascade Screening for Awareness and Detection-FH Registry by de Ferranti, Sarah D., Shrader, Peter, Linton, MacRae F., Knowles, Joshua W., Hudgins, Lisa C., Benuck, Irwin, Kindt, Iris, O'Brien, Emily C., Peterson, Amy L., Ahmad, Zahid S., Clauss, Sarah, Duell, P. Barton, Shapiro, Michael D., Wilemon, Katherine, Gidding, Samuel S., Neal, William

“…To describe enrollment characteristics of youth in the Cascade Screening for Awareness and Detection of FH Registry. This is a cross-sectional analysis of 493…”
Get full text

Why do sweets fatten our livers? by Hudgins, Lisa C

Get full text

Contemporary Homozygous Familial Hypercholesterolemia in the United States: Insights From the CASCADE FH Registry by Cuchel, Marina, Lee, Paul C, Hudgins, Lisa C, Duell, P Barton, Ahmad, Zahid, Baum, Seth J, Linton, MacRae F, de Ferranti, Sarah D, Ballantyne, Christie M, Larry, John A, Hemphill, Linda C, Kindt, Iris, Gidding, Samuel S, Martin, Seth S, Moriarty, Patrick M, Thompson, Paul P, Underberg, James A, Guyton, John R, Andersen, Rolf L, Whellan, David J, Benuck, Irwin, Kane, John P, Myers, Kelly, Howard, William, Staszak, David, Jamison, Allison, Card, Mary C, Bourbon, Mafalda, Chora, Joana R, Rader, Daniel J, Knowles, Joshua W, Wilemon, Katherine, McGowan, Mary P

“…Background Homozygous familial hypercholesterolemia (HoFH) is a rare, treatment-resistant disorder characterized by early-onset atherosclerotic and aortic…”
Get full text

Cardiovascular outcomes in patients with homozygous familial hypercholesterolaemia on lipoprotein apheresis initiated during childhood: long-term follow-up of an international cohort from two registries by Reijman, M Doortje, Tromp, Tycho R, Hutten, Barbara A, Hovingh, G Kees, Blom, Dirk J, Catapano, Alberico L, Cuchel, Marina, Dann, Eldad J, Gallo, Antonio, Hudgins, Lisa C, Raal, Frederick J, Ray, Kausik K, Sadiq, Fouzia, Soran, Handrean, Groothoff, Jaap W, Wiegman, Albert, Kusters, D Meeike

“…Homozygous familial hypercholesterolaemia (HoFH) is a rare genetic disease characterised by extremely high plasma LDL cholesterol from birth, causing…”
Get more information