Search Results - "Hudecová, Soňa"

SB203580, a specific inhibitor of p38-MAPK pathway, is a new reversal agent of P-glycoprotein-mediated multidrug resistance by Barančı́k, Miroslav, Boháčová, Vierka, Kvačkajová, Janka, Hudecová, Soňa, Križanová, Ol’ga, Breier, Albert

“…P-glycoprotein (P-gp) is the plasma membrane transport pump responsible for efflux of chemotherapeutic agents from cells and is one of the systems that secures…”
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Type 3 inositol 1,4,5-trisphosphate receptor has antiapoptotic and proliferative role in cancer cells by Rezuchova, Ingeborg, Hudecova, Sona, Soltysova, Andrea, Matuskova, Miroslava, Durinikova, Erika, Chovancova, Barbora, Zuzcak, Michal, Cihova, Marina, Burikova, Monika, Penesova, Adela, Lencesova, Lubomira, Breza, Jan, Krizanova, Olga

“…Although the involvement of type 1 (IP 3 R1) and type 2 (IP 3 R2) inositol 1,4,5-trisphosphate receptors in apoptosis induction has been well documented in…”
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Endogenous H2S producing enzymes are involved in apoptosis induction in clear cell renal cell carcinoma by Breza, Jan, Soltysova, Andrea, Hudecova, Sona, Penesova, Adela, Szadvari, Ivan, Babula, Petr, Chovancova, Barbora, Lencesova, Lubomira, Pos, Ondrej, Ondrias, Karol, Krizanova, Olga

“…Background Knowledge about the expression and thus a role of enzymes that produce endogenous H.sub.2S - cystathionine-[beta]-synthase, cystathionine…”
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Melatonin-Induced Changes in Cytosolic Calcium Might be Responsible for Apoptosis Induction in Tumour Cells by Chovancova, Barbora, Hudecova, Sona, Lencesova, Lubomira, Babula, Petr, Rezuchova, Ingeborg, Penesova, Adela, Grman, Marian, Moravcik, Roman, Zeman, Michal, Krizanova, Olga

“…Background/Aims: Melatonin is a hormone transferring information about duration of darkness to the organism and is known to modulate several signaling pathways…”
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Haloperidol Affects Plasticity of Differentiated NG-108 Cells Through σ1R/IP3R1 Complex by Kubickova, Jana, Lencesova, Lubomira, Csaderova, Lucia, Stracina, Tibor, Hudecova, Sona, Babula, Petr, Rozborilova, Eva, Novakova, Marie, Krizanova, Olga

“…Haloperidol is an antipsychotic agent that primarily acts as an antagonist of D2 dopamine receptors. Besides other receptor systems, it targets sigma 1…”
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Calcium and ROS: A mutual interplay by Görlach, Agnes, Bertram, Katharina, Hudecova, Sona, Krizanova, Olga

“…Calcium is an important second messenger involved in intra- and extracellular signaling cascades and plays an essential role in cell life and death decisions…”
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Nuclear all-trans retinoic acid receptors by Brtko, Julius, Filipčík, Peter, Hudecová, Soňa, Brtková, Anastázia, Bransová, Janette

“…The present study was undertaken to investigate the effects of selenite (SeIV) and selenate (SeVI) on the all-trans retinoic acid (RA)-nuclear retinoic acid…”
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Purification of the homogentisic acid oxidase from mammalian liver by Hudecová, Soňa, Straková, Zuzana, Krianova, Olga

“…Alkaptonuria is a rare human autosomal recessive disease caused by the lack of homogentisic acid oxidase (HTO) activity. This enzyme, produced mainly in liver,…”
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Calcium signaling affects migration and proliferation differently in individual cancer cells due to nifedipine treatment by Chovancova, Barbora, Liskova, Veronika, Miklikova, Svetlana, Hudecova, Sona, Babula, Petr, Penesova, Adela, Sevcikova, Angelika, Durinikova, Erika, Novakova, Marie, Matuskova, Miroslava, Krizanova, Olga

“…[Display omitted] Several papers have reported that calcium channel blocking drugs were associated with increased breast cancer risk and worsened prognosis…”
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Sodium/calcium exchanger is involved in apoptosis induced by H2S in tumor cells through decreased levels of intracellular pH by Szadvari, Ivan, Hudecova, Sona, Chovancova, Barbora, Matuskova, Miroslava, Cholujova, Dana, Lencesova, Lubomira, Valerian, David, Ondrias, Karol, Babula, Petr, Krizanova, Olga

“…We explored possibility that sodium/calcium exchanger 1 (NCX1) is involved in pH modulation and apoptosis induction in GYY4137 treated cells. We have shown…”
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Type 1 Sodium Calcium Exchanger Forms a Complex with Carbonic Anhydrase IX and Via Reverse Mode Activity Contributes to pH Control in Hypoxic Tumors by Liskova, Veronika, Hudecova, Sona, Lencesova, Lubomira, Iuliano, Filippo, Sirova, Marta, Ondrias, Karol, Pastorekova, Silvia, Krizanova, Olga

“…Hypoxia and acidosis are among the key microenvironmental factors that contribute to cancer progression. We have explored a possibility that the type 1Na /Ca…”
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Hypoxic conditions increases H2S-induced ER stress in A2870 cells by Lencesova, Lubomira, Vlcek, Miroslav, Krizanova, Olga, Hudecova, Sona

“…Hypoxia—a state of lower oxygen demand—is responsible for a higher aggressiveness of tumors and therefore a worse prognosis. During hypoxia, several metabolic…”
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Polysulfides and products of H2S/S-nitrosoglutathione in comparison to H2S, glutathione and antioxidant Trolox are potent scavengers of superoxide anion radical and produce hydroxyl radical by decomposition of H2O2 by Misak, Anton, Grman, Marian, Bacova, Zuzana, Rezuchova, Ingeborg, Hudecova, Sona, Ondriasova, Elena, Krizanova, Olga, Brezova, Vlasta, Chovanec, Miroslav, Ondrias, Karol

“…Exogenous and endogenously produced sulfide derivatives, such as H2S/HS−/S2−, polysulfides and products of the H2S/S-nitrosoglutathione interaction (S/GSNO),…”
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Polysulfides and products of H 2 S/S-nitrosoglutathione in comparison to H 2 S, glutathione and antioxidant Trolox are potent scavengers of superoxide anion radical and produce hydroxyl radical by decomposition of H 2 O 2 by Misak, Anton, Grman, Marian, Bacova, Zuzana, Rezuchova, Ingeborg, Hudecova, Sona, Ondriasova, Elena, Krizanova, Olga, Brezova, Vlasta, Chovanec, Miroslav, Ondrias, Karol

“…Exogenous and endogenously produced sulfide derivatives, such as H S/HS /S , polysulfides and products of the H S/S-nitrosoglutathione interaction (S/GSNO),…”
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Nuclear all-trans retinoic acid receptors: in vitro effects of selenium by Brtko, J, Filipcik, P, Hudecova, S, Brtkova, A, Bransova, J

“…The present study was undertaken to investigate the effects of selenite (SeIV) and selenate (SeVI) on the all-trans retinoic acid (RA)-nuclear retinoic acid…”
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Sodium/calcium exchanger is upregulated by sulfide signaling, forms complex with the beta 1 and beta 3 but not beta 2 adrenergic receptors, and induces apoptosis by Markova, Jana, Hudecova, Sona, Soltysova, Andrea, Sirova, Marta, Csaderova, Lucia, Lencesova, Lubomira, Ondrias, Karol, Krizanova, Olga

“…Hydrogen sulfide (H sub(2)S) as a novel gasotransmitter regulates variety of processes, including calcium transport systems. Sodium calcium exchanger (NCX) is…”
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Sodium/calcium exchanger is upregulated by sulfide signaling, forms complex with the β1 and β3 but not β2 adrenergic receptors, and induces apoptosis by Markova, Jana, Hudecova, Sona, Soltysova, Andrea, Sirova, Marta, Csaderova, Lucia, Lencesova, Lubomira, Ondrias, Karol, Krizanova, Olga

“…Hydrogen sulfide (H 2 S) as a novel gasotransmitter regulates variety of processes, including calcium transport systems. Sodium calcium exchanger (NCX) is one…”
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Sodium/calcium exchanger is involved in apoptosis induced by H 2 S in tumor cells through decreased levels of intracellular pH by Szadvari, Ivan, Hudecova, Sona, Chovancova, Barbora, Matuskova, Miroslava, Cholujova, Dana, Lencesova, Lubomira, Valerian, David, Ondrias, Karol, Babula, Petr, Krizanova, Olga

“…We explored possibility that sodium/calcium exchanger 1 (NCX1) is involved in pH modulation and apoptosis induction in GYY4137 treated cells. We have shown…”
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NF-κB inhibition significantly upregulates the norepinephrine transporter system, causes apoptosis in pheochromocytoma cell lines and prevents metastasis in an animal model by Pacak, Karel, Sirova, Marta, Giubellino, Alessio, Lencesova, Lubomira, Csaderova, Lucia, Laukova, Marcela, Hudecova, Sona, Krizanova, Olga

“…Pheochromocytomas (PHEOs) and paragangliomas (PGLs) are specific types of neuroendocrine tumors that originate in the adrenal medulla or…”
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Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy by PASTOREK, MICHAL, SIMKO, VERONIKA, TAKACOVA, MARTINA, BARATHOVA, MONIKA, BARTOSOVA, MARIA, HUNAKOVA, LUBA, SEDLAKOVA, OLGA, HUDECOVA, SONA, KRIZANOVA, OLGA, DEQUIEDT, FRANCK, PASTOREKOVA, SILVIA, SEDLAK, JAN

“…One of the recently emerging anticancer strategies is the use of natural dietary compounds, such as sulforaphane, a cancer-chemopreventive isothiocyanate found…”
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