Search Results - "Hudak, Edward"
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Parsimonious Discovery of Synergistic Drug Combinations
Published in ACS chemical biology (16-12-2011)“…Combination therapies that enhance efficacy or permit reduced dosages to be administered have seen great success in a variety of therapeutic applications. More…”
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Journal Article -
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Live Cell Membranome cDNA Screen: A Novel Homogenous Live Cell Binding Assay to Study Membrane Protein-Ligand Interaction
Published in SLAS discovery (01-12-2019)“…Interactions between transmembrane receptors and their ligands play important roles in normal biological processes and pathological conditions. However, the…”
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Journal Article -
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Identification of small-molecule modulators of mouse SVZ progenitor cell proliferation and differentiation through high-throughput screening
Published in Journal of biomolecular screening (01-04-2009)“…Adult mouse subventricular zone (SVZ) neural stem/progenitor cells are multipotent self-renewing cells that retain the capacity to generate the major cell…”
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Journal Article -
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A 1,536-well ultra-high-throughput siRNA screen to identify regulators of the Wnt/beta-catenin pathway
Published in Assay and drug development technologies (01-06-2010)“…High-throughput siRNA screens are now widely used for identifying novel drug targets and mapping disease pathways. Despite their popularity, there remain…”
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Journal Article -
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THE ISOMERIC NORMAL NONYNOIC ACIDS
Published in Journal of organic chemistry (01-10-1954)Get full text
Journal Article -
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Protein and Cell Surface Engineering with Oxime Conjugates
Published 01-01-2013“…Chapter 1 outlines my work on utilizing the genetically encoded consensus sequence termed the aldehyde tag to introduce a bioorthogonal carbonyl group onto…”
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Dissertation -
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Protein and Cell Surface Engineering with Oxime Conjugates
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Dissertation -
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Compiling parallel loops for high performance computers: Partitioning, data assignment, and remapping
Published 01-01-1992“…Communication overhead in multiprocessor systems, as exemplified by cache coherency traffic and global memory access, has a substantial impact on…”
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Dissertation