Search Results - "Hubert, Mathieu"

Syncytia formation by SARS‐CoV‐2‐infected cells by Buchrieser, Julian, Dufloo, Jérémy, Hubert, Mathieu, Monel, Blandine, Planas, Delphine, Rajah, Maaran Michael, Planchais, Cyril, Porrot, Françoise, Guivel‐Benhassine, Florence, Van der Werf, Sylvie, Casartelli, Nicoletta, Mouquet, Hugo, Bruel, Timothée, Schwartz, Olivier

“…Severe cases of COVID‐19 are associated with extensive lung damage and the presence of infected multinucleated syncytial pneumocytes. The viral and cellular…”
Get full text

SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance by Robinot, Rémy, Hubert, Mathieu, de Melo, Guilherme Dias, Lazarini, Françoise, Bruel, Timothée, Smith, Nikaïa, Levallois, Sylvain, Larrous, Florence, Fernandes, Julien, Gellenoncourt, Stacy, Rigaud, Stéphane, Gorgette, Olivier, Thouvenot, Catherine, Trébeau, Céline, Mallet, Adeline, Duménil, Guillaume, Gobaa, Samy, Etournay, Raphaël, Lledo, Pierre-Marie, Lecuit, Marc, Bourhy, Hervé, Duffy, Darragh, Michel, Vincent, Schwartz, Olivier, Chakrabarti, Lisa A.

“…Understanding how SARS-CoV-2 spreads within the respiratory tract is important to define the parameters controlling the severity of COVID-19. Here we examine…”
Get full text

Syncytia formation by SARS‐CoV‐2‐infected cells by Buchrieser, Julian, Dufloo, Jérémy, Hubert, Mathieu, Monel, Blandine, Planas, Delphine, Rajah, Maaran Michael, Planchais, Cyril, Porrot, Françoise, Guivel‐Benhassine, Florence, Van der Werf, Sylvie, Casartelli, Nicoletta, Mouquet, Hugo, Bruel, Timothée, Schwartz, Olivier

Get full text

Mother-to-Child Transmission of Arboviruses during Breastfeeding: From Epidemiology to Cellular Mechanisms by Desgraupes, Sophie, Hubert, Mathieu, Gessain, Antoine, Ceccaldi, Pierre-Emmanuel, Vidy, Aurore

“…Most viruses use several entry sites and modes of transmission to infect their host (parenteral, sexual, respiratory, oro-fecal, transplacental,…”
Get full text

STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses by Vila, Isabelle K., Chamma, Hanane, Steer, Alizée, Saccas, Mathilde, Taffoni, Clara, Turtoi, Evgenia, Reinert, Line S., Hussain, Saqib, Marines, Johanna, Jin, Lei, Bonnefont, Xavier, Hubert, Mathieu, Schwartz, Olivier, Paludan, Soren R., Van Simaeys, Gaetan, Doumont, Gilles, Sobhian, Bijan, Vlachakis, Dimitrios, Turtoi, Andrei, Laguette, Nadine

“…Concerted alteration of immune and metabolic homeostasis underlies several inflammation-related pathologies, ranging from metabolic syndrome to infectious…”
Get full text

Endolysosomal channel TMEM175 mediates antitoxin activity of DABMA by Wu, Yu, Huang, Jiamin, Zhang, Fei, Guivel‐Benhassine, Florence, Hubert, Mathieu, Schwartz, Olivier, Xiao, Weihua, Cintrat, Jean‐Christophe, Qu, Lili, Barbier, Julien, Gillet, Daniel, Cang, Chunlei

“…DABMA is a chemical molecule optimized from the parent compound ABMA and exhibits broad‐spectrum antipathogenic activity by modulating the host's endolysosomal…”
Get full text

Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion by Planas, Delphine, Staropoli, Isabelle, Michel, Vincent, Lemoine, Frederic, Donati, Flora, Prot, Matthieu, Porrot, Francoise, Guivel-Benhassine, Florence, Jeyarajah, Banujaa, Brisebarre, Angela, Dehan, Océane, Avon, Léa, Bolland, William Henry, Hubert, Mathieu, Buchrieser, Julian, Vanhoucke, Thibault, Rosenbaum, Pierre, Veyer, David, Péré, Hélène, Lina, Bruno, Trouillet-Assant, Sophie, Hocqueloux, Laurent, Prazuck, Thierry, Simon-Loriere, Etienne, Schwartz, Olivier

“…The unceasing circulation of SARS-CoV-2 leads to the continuous emergence of novel viral sublineages. Here, we isolate and characterize XBB.1, XBB.1.5,…”
Get full text

A Corning perspective on the future of technical glass in our evolving world by Kohli, Jeffrey T., Hubert, Mathieu, Youngman, Randall E., Morse, David L.

“…Glass is a material with a rich history and a bright future. Due to its outstanding properties and its versatility, it is a key material in many applications…”
Get full text

Mpox Hepatic and Pulmonary Lesions in HIV/Hepatitis B Virus Co-Infected Patient, France by Calin, Ruxandra, Périllaud-Dubois, Claire, Marot, Stéphane, Kerrou, Khaldoun, Peytavin, Gilles, Bachir, Marwa, Kirch, Anne Laure, Lassel, Ludovic, Fallet, Vincent, Gozlan, Joel, Pain, Jean Baptiste, Senet, Patricia, Ferraris, Olivier, Bine, Sébastien, Hubert, Mathieu, Schwartz, Olivier, Morand-Joubert, Laurence, Pialoux, Gilles

“…We report a case of persistent disseminated mpox evolving over >6 months in an HIV/hepatitis B virus co-infected patient in France who had <200 CD4+ cells/mm ,…”
Get full text

SARS‐CoV‐2 Alpha, Beta, and Delta variants display enhanced Spike‐mediated syncytia formation by Rajah, Maaran Michael, Hubert, Mathieu, Bishop, Elodie, Saunders, Nell, Robinot, Remy, Grzelak, Ludivine, Planas, Delphine, Dufloo, Jérémy, Gellenoncourt, Stacy, Bongers, Alice, Zivaljic, Marija, Planchais, Cyril, Guivel‐Benhassine, Florence, Porrot, Françoise, Mouquet, Hugo, Chakrabarti, Lisa A, Buchrieser, Julian, Schwartz, Olivier

“…Severe COVID‐19 is characterized by lung abnormalities, including the presence of syncytial pneumocytes. Syncytia form when SARS‐CoV‐2 spike protein expressed…”
Get full text

Productive Infection of Mouse Mammary Glands and Human Mammary Epithelial Cells by Zika Virus by Hubert, Mathieu, Chiche, Aurélie, Legros, Vincent, Jeannin, Patricia, Montange, Thomas, Gessain, Antoine, Ceccaldi, Pierre-Emmanuel, Vidy, Aurore

“…Zika virus (ZIKV) belongs to the large category of arboviruses. Surprisingly, several human-to-human transmissions of ZIKV have been notified, either following…”
Get full text

Evidence That Zika Virus Is Transmitted by Breastfeeding to Newborn A129 (Ifnar1 Knock-Out) Mice and Is Able to Infect and Cross a Tight Monolayer of Human Intestinal Epithelial Cells by Hubert, Mathieu, Jeannin, Patricia, Burlaud-Gaillard, Julien, Roingeard, Philippe, Gessain, Antoine, Ceccaldi, Pierre-Emmanuel, Vidy, Aurore

“…Zika virus (ZIKV) belongs to the Flavivirus genus in the Flaviviridae family. Mainly transmitted via mosquito bites (Aedes aegypti, Aedes albopictus), ZIKV has…”
Get full text

L’ÉVÉNEMENT ET LE TRAGIQUE: SUR LE CARACTÈRE INDIGESTE DE LA PHILOSOPHIE DE CLÉMENT ROSSET by Mathieu Hubert

“…La “période tragiqueˮ, de La philosophie tragique (1960) à L’anti-nature (1973), marque le premier moment de la philosophie de Clément Rosset. Nous y…”
Get full text

The FDA-approved drug Auranofin has a dual inhibitory effect on SARS-CoV-2 entry and NF-κB signaling by Laplantine, Emmanuel, Chable-Bessia, Christine, Oudin, Anne, Swain, Jitendryia, Soria, Adèle, Merida, Peggy, Gourdelier, Manon, Mestiri, Sarra, Besseghe, Indira, Bremaud, Erwan, Neyret, Aymeric, Lyonnais, Sebastien, Favard, Cyril, Benaroch, Philippe, Hubert, Mathieu, Schwartz, Olivier, Guerin, Maryse, Danckaert, Anne, Del Nery, Elaine, Muriaux, Delphine, Weil, Robert

“…Patients with severe COVID-19 show an altered immune response that fails to control the viral spread and suffer from exacerbated inflammatory response, which…”
Get full text

Human Claudin-Derived Peptides Block the Membrane Fusion Process of Zika Virus and Are Broad Flavivirus Inhibitors by Zoladek, Jim, Burlaud-Gaillard, Julien, Chazal, Maxime, Desgraupes, Sophie, Jeannin, Patricia, Gessain, Antoine, Pardigon, Nathalie, Hubert, Mathieu, Roingeard, Philippe, Jouvenet, Nolwenn, Afonso, Philippe V

“…Zika virus (ZIKV) is a mosquito-borne flavivirus that emerged in the Pacific islands in 2007 and spread to the Americas in 2015. The infection remains…”
Get full text

Aggregative Variational Inequalities by von Mouche, Peter Hubert Mathieu, Szidarovszky, Ferenc

“…We enrich the theory of variational inequalities in the case of an aggregative structure by implementing recent results obtained by using the…”
Get full text

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing by Gordon, David E, Jang, Gwendolyn M, Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M, O'Meara, Matthew J, Rezelj, Veronica V, Guo, Jeffrey Z, Swaney, Danielle L, Tummino, Tia A, Hüttenhain, Ruth, Kaake, Robyn M, Richards, Alicia L, Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J, Braberg, Hannes, Fabius, Jacqueline M, Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J, Cakir, Merve, McGregor, Michael J, Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Mac Kain, Alice, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T, Melnyk, James E, Chorba, John S, Lou, Kevin, Dai, Shizhong A, Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher J P, Perica, Tina, Pilla, Kala Bharath, Ganesan, Sai J, Saltzberg, Daniel J, Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B, Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A, Bohn, Markus, Safari, Maliheh, Ugur, Fatima S, Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J, O'Neal, Michael C, Cai, Yiming, Chang, Jason C J, Broadhurst, David J, Klippsten, Saker, Sharp, Phillip P, Wenzell, Nicole A, Kuzuoglu-Ozturk, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M, Cavero, Devin A, Hiatt, Joseph, Roth, Theodore L, Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M, Frankel, Alan D, Rosenberg, Oren S, Verba, Kliment A, Agard, David A, Ott, Melanie, Emerman, Michael, Jura, Natalia

“…A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019…”
Get full text

Endolysosomal channel TMEM 175 mediates antitoxin activity of DABMA by Wu, Yu, Huang, Jiamin, Zhang, Fei, Guivel‐Benhassine, Florence, Hubert, Mathieu, Schwartz, Olivier, Xiao, Weihua, Cintrat, Jean‐Christophe, Qu, Lili, Barbier, Julien, Gillet, Daniel, Cang, Chunlei

“…DABMA is a chemical molecule optimized from the parent compound ABMA and exhibits broad‐spectrum antipathogenic activity by modulating the host's endolysosomal…”
Get full text

Celebrating Optical Glass – the International Year of Glass (2022): feature issue introduction by Ballato, John, Fotheringham, Ulrich, Hubert, Mathieu, Nolte, Stefan, Petit, Laeticia, Richardson, Kathleen A.

“…We introduce the Optical Materials Express feature issue that celebrates historic and recent advances in optical glass. In honor of the United Nations…”
Get full text

High fusion and cytopathy of SARS-CoV-2 variant B.1.640.1 by Bolland, William, Michel, Vincent, Planas, Delphine, Hubert, Mathieu, Staropoli, Isabelle, Guivel-Benhassine, Florence, Porrot, Françoise, N'Debi, Mélissa, Rodriguez, Christophe, Fourati, Slim, Prot, Matthieu, Planchais, Cyril, Hocqueloux, Laurent, Simon-Lorière, Etienne, Mouquet, Hugo, Prazuck, Thierry, Pawlotsky, Jean-Michel, Bruel, Timothée, Schwartz, Olivier, Buchrieser, Julian

“…SARS-CoV-2 variants with undetermined properties have emerged intermittently throughout the COVID-19 pandemic. Some variants possess unique phenotypes and…”
Get full text