Search Results - "Hubert, Catherine B."
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Metabolomic approaches for enzyme function and pathway discovery in bacteria
Published in Methods in enzymology (2022)“…Most of the chemical diversity present in the natural world derives from the incredible ability of enzymes to act on and control metabolism. Yet, thousands of…”
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In vitro elucidation of the crucial but complex oxidative tailoring steps in rufomycin biosynthesis enables one pot conversion of rufomycin B to rufomycin C
Published in Chemical communications (Cambridge, England) (09-11-2021)“…The antimycobacterial peptides, rufomycins, have their antibiotic activity conferred by oxidative tailoring of the cyclic peptide. Here we elucidate the roles…”
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New chemistry from natural product biosynthesis
Published in Biochemical Society transactions (15-06-2016)“…Catalysts are a vital part of synthetic chemistry. However, there are still many important reactions for which catalysts have not been developed. The use of…”
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Vitamin B5 supports MYC oncogenic metabolism and tumor progression in breast cancer
Published in Nature metabolism (01-11-2023)“…Tumors are intrinsically heterogeneous and it is well established that this directs their evolution, hinders their classification and frustrates therapy 1 – 3…”
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Convergence and divergence in the metabolic network of Mycobacterium tuberculosis
Published in Current opinion in systems biology (01-12-2021)“…Metabolism is still often regarded as a set of canonical reactions, identical in all organisms, yet that is far from correct. Metabolism and the metabolic…”
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Vitamin B 5 supports MYC oncogenic metabolism and tumor progression in breast cancer
Published in Nature metabolism (01-11-2023)“…Tumors are intrinsically heterogeneous and it is well established that this directs their evolution, hinders their classification and frustrates therapy …”
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