Search Results - "Huber, Stefan T."

Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake by Jakobi, Arjen J., Huber, Stefan T., Mortensen, Simon A., Schultz, Sebastian W., Palara, Anthimi, Kuhm, Tanja, Shrestha, Birendra Kumar, Lamark, Trond, Hagen, Wim J. H., Wilmanns, Matthias, Johansen, Terje, Brech, Andreas, Sachse, Carsten

“…p62/SQSTM1 is an autophagy receptor and signaling adaptor with an N-terminal PB1 domain that forms the scaffold of phase-separated p62 bodies in the cell. The…”
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Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes by Huber, Stefan T, Sarajlic, Edin, Huijink, Roeland, Weis, Felix, Evers, Wiel H, Jakobi, Arjen J

“…Cryogenic electron microscopy has become an essential tool for structure determination of biological macromolecules. In practice, the difficulty to reliably…”
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Large-Scale Mapping of Axonal Arbors Using High-Density Microelectrode Arrays by Bullmann, Torsten, Radivojevic, Milos, Huber, Stefan T., Deligkaris, Kosmas, Hierlemann, Andreas, Frey, Urs

“…Understanding the role of axons in neuronal information processing is a fundamental task in neuroscience. Over the last years, sophisticated patch-clamp…”
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PspA adopts an ESCRT-III-like fold and remodels bacterial membranes by Junglas, Benedikt, Huber, Stefan T., Heidler, Thomas, Schlösser, Lukas, Mann, Daniel, Hennig, Raoul, Clarke, Mairi, Hellmann, Nadja, Schneider, Dirk, Sachse, Carsten

“…PspA is the main effector of the phage shock protein (Psp) system and preserves the bacterial inner membrane integrity and function. Here, we present the 3.6 Å…”
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Cryo-EM structure of gas vesicles for buoyancy-controlled motility by Huber, Stefan T., Terwiel, Dion, Evers, Wiel H., Maresca, David, Jakobi, Arjen J.

“…Gas vesicles are gas-filled nanocompartments that allow a diverse group of bacteria and archaea to control their buoyancy. The molecular basis of their…”
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Automated tracing of helical assemblies from electron cryo-micrographs by Huber, Stefan T., Kuhm, Tanja, Sachse, Carsten

“…Structure determination of helical specimens commonly requires datasets from thousands of micrographs often obtained by automated cryo-EM data acquisition…”
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Structure and assembly of ESCRT-III helical Vps24 filaments by Huber, Stefan T, Mostafavi, Siavash, Mortensen, Simon A, Sachse, Carsten

“…ESCRT-III proteins mediate a range of cellular membrane remodeling activities such as multivesicular body biogenesis, cytokinesis, and viral release. Critical…”
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Structural basis of antimicrobial membrane coat assembly by human GBP1 by Kuhm, Tanja, Taisne, Clémence, de Agrela Pinto, Cecilia, Gross, Luca, Giannopoulou, Evdokia A, Huber, Stefan T, Pardon, Els, Steyaert, Jan, Tans, Sander J, Jakobi, Arjen J

“…Guanylate-binding proteins (GBPs) are interferon-inducible guanosine triphosphate hydrolases (GTPases) mediating host defense against intracellular pathogens…”
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