Search Results - "Huber, Samuel"

Microplastics detected in cirrhotic liver tissue by Horvatits, Thomas, Tamminga, Matthias, Liu, Beibei, Sebode, Marcial, Carambia, Antonella, Fischer, Lutz, Püschel, Klaus, Huber, Samuel, Fischer, Elke Kerstin

“…The contamination of ecosystem compartments by microplastics (MPs) is an ubiquitous problem. MPs have been observed in mice tissues, and recently in human…”
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Biological Chromium(VI) Reduction in the Cathode of a Microbial Fuel Cell by Tandukar, Madan, Huber, Samuel J, Onodera, Takashi, Pavlostathis, Spyros G

“…The biocathode of a microbial fuel cell (MFC) offers a promising potential for the reductive treatment of oxidized pollutants. In this study, we demonstrated…”
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Regulation of TH17 Cells and Associated Cytokines in Wound Healing, Tissue Regeneration, and Carcinogenesis by Brockmann, Leonie, Giannou, Anastasios, Gagliani, Nicola, Huber, Samuel

“…Wound healing is a crucial process which protects our body against permanent damage and invasive infectious agents. Upon tissue damage, inflammation is an…”
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Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer by Hu, Bo, Elinav, Eran, Huber, Samuel, Strowig, Till, Hao, Liming, Hafemann, Anja, Jin, Chengcheng, Eisenbarth, Stephanie C., Flavell, Richard A.

“…The microbiota is pivotal in the pathogenesis of inflammatory bowel disease (IBD)-associated inflammation-induced colorectal cancer (CRC), yet mechanisms for…”
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IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine by Huber, Samuel, Gagliani, Nicola, Zenewicz, Lauren A., Huber, Francis J., Bosurgi, Lidia, Hu, Bo, Hedl, Matija, Zhang, Wei, O’Connor, William, Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Booth, Carmen J., Cho, Judy H., Ouyang, Wenjun, Abraham, Clara, Flavell, Richard A.

“…IL-22 is one of the factors that, although important for wound healing, also promote tumorigenesis; the regulation of IL-22BP, the IL-22 binding protein, via…”
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TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer by Perez, Laura Garcia, Kempski, Jan, McGee, Heather M., Pelzcar, Penelope, Agalioti, Theodora, Giannou, Anastasios, Konczalla, Leonie, Brockmann, Leonie, Wahib, Ramez, Xu, Hao, Vesely, Maria Carolina Amezcua, Soukou, Shiwa, Steglich, Babett, Bedke, Tanja, Manthey, Carolin, Seiz, Oliver, Diercks, Björn-Philipp, Gnafakis, Stylianos, Guse, Andreas H., Perez, Daniel, Izbicki, Jakob R., Gagliani, Nicola, Flavell, Richard A., Huber, Samuel

“…IL-22 has dual functions during tumorigenesis. Short term IL-22 production protects against genotoxic stress, whereas uncontrolled IL-22 activity promotes…”
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Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression by Calcinotto, Arianna, Brevi, Arianna, Chesi, Marta, Ferrarese, Roberto, Garcia Perez, Laura, Grioni, Matteo, Kumar, Shaji, Garbitt, Victoria M., Sharik, Meaghen E., Henderson, Kimberly J., Tonon, Giovanni, Tomura, Michio, Miwa, Yoshihiro, Esplugues, Enric, Flavell, Richard A., Huber, Samuel, Canducci, Filippo, Rajkumar, Vincent S., Bergsagel, P. Leif, Bellone, Matteo

“…The gut microbiota has been causally linked to cancer, yet how intestinal microbes influence progression of extramucosal tumors is poorly understood. Here we…”
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Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4 by Hu, Bo, Elinav, Eran, Huber, Samuel, Booth, Carmen J., Strowig, Till, Jin, Chengcheng, Eisenbarth, Stephanie C., Flavell, Richard A.

“…Chronic inflammation is a known risk factor for tumorigenesis, yet the precise mechanism of this association is currently unknown. The inflammasome, a…”
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Control of TH17 cells occurs in the small intestine by Esplugues, Enric, Huber, Samuel, Gagliani, Nicola, Hauser, Anja E., Town, Terrence, Wan, Yisong Y., O’Connor, William, Rongvaux, Anthony, Van Rooijen, Nico, Haberman, Ann M., Iwakura, Yoichiro, Kuchroo, Vijay K., Kolls, Jay K., Bluestone, Jeffrey A., Herold, Kevan C., Flavell, Richard A.

“…Keeping T H 17 cells under wraps Interleukin-17-producing T helper (T H 17) cells serve an important role in the immune system, but are strongly implicated in…”
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DISCERN: deep single-cell expression reconstruction for improved cell clustering and cell subtype and state detection by Hausmann, Fabian, Ergen, Can, Khatri, Robin, Marouf, Mohamed, Hänzelmann, Sonja, Gagliani, Nicola, Huber, Samuel, Machart, Pierre, Bonn, Stefan

“…Abstract Background Single-cell sequencing provides detailed insights into biological processes including cell differentiation and identity. While providing…”
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Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney by Krebs, Christian F., Paust, Hans-Joachim, Krohn, Sonja, Koyro, Tobias, Brix, Silke R., Riedel, Jan-Hendrik, Bartsch, Patricia, Wiech, Thorsten, Meyer-Schwesinger, Catherine, Huang, Jiabin, Fischer, Nicole, Busch, Philipp, Mittrücker, Hans-Willi, Steinhoff, Ulrich, Stockinger, Brigitta, Perez, Laura Garcia, Wenzel, Ulrich O., Janneck, Matthias, Steinmetz, Oliver M., Gagliani, Nicola, Stahl, Rolf A.K., Huber, Samuel, Turner, Jan-Eric, Panzer, Ulf

“…Th17 cells are most abundant in the gut, where their presence depends on the intestinal microbiota. Here, we examined whether intestinal Th17 cells contribute…”
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Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation by Emgård, Johanna, Kammoun, Hana, García-Cassani, Bethania, Chesné, Julie, Parigi, Sara M., Jacob, Jean-Marie, Cheng, Hung-Wei, Evren, Elza, Das, Srustidhar, Czarnewski, Paulo, Sleiers, Natalie, Melo-Gonzalez, Felipe, Kvedaraite, Egle, Svensson, Mattias, Scandella, Elke, Hepworth, Matthew R., Huber, Samuel, Ludewig, Burkhard, Peduto, Lucie, Villablanca, Eduardo J., Veiga-Fernandes, Henrique, Pereira, João P., Flavell, Richard A., Willinger, Tim

“…Group 3 innate lymphoid cells (ILC3s) sense environmental signals and are critical for tissue integrity in the intestine. Yet, which signals are sensed and…”
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Distinct Microbial Communities Trigger Colitis Development upon Intestinal Barrier Damage via Innate or Adaptive Immune Cells by Roy, Urmi, Gálvez, Eric J.C., Iljazovic, Aida, Lesker, Till Robin, Błażejewski, Adrian J., Pils, Marina C., Heise, Ulrike, Huber, Samuel, Flavell, Richard A., Strowig, Till

“…Inflammatory bowel disease comprises a group of heterogeneous diseases characterized by chronic and relapsing mucosal inflammation. Alterations in microbiota…”
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Tissue Sampling and Homogenization in the Sub-Microliter Scale with a Nanosecond Infrared Laser (NIRL) for Mass Spectrometric Proteomics by Hahn, Jan, Moritz, Manuela, Voß, Hannah, Pelczar, Penelope, Huber, Samuel, Schlüter, Hartmut

“…It was recently shown that ultrashort pulse infrared (IR) lasers, operating at the wavelength of the OH vibration stretching band of water, are highly…”
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IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo by Brockmann, Leonie, Gagliani, Nicola, Steglich, Babett, Giannou, Anastasios D, Kempski, Jan, Pelczar, Penelope, Geffken, Maria, Mfarrej, Bechara, Huber, Francis, Herkel, Johannes, Wan, Yisong Y, Esplugues, Enric, Battaglia, Manuela, Krebs, Christian F, Flavell, Richard A, Huber, Samuel

“…IL-10 is essential to maintain intestinal homeostasis. CD4 T regulatory type 1 (T 1) cells produce large amounts of this cytokine and are therefore currently…”
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Life, death, and miracles: Th17 cells in the intestine by Huber, Samuel, Gagliani, Nicola, Flavell, Richard A.

“…Th17 cells, a distinct subset of CD4+ T‐helper cells, are commonly associated with chronic inflammatory and autoimmune diseases; however, Th17 cells also…”
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TH17 Cell and Epithelial Cell Crosstalk during Inflammatory Bowel Disease and Carcinogenesis by Kempski, Jan, Brockmann, Leonie, Gagliani, Nicola, Huber, Samuel

“…The intestine is colonized by hundreds of different species of commensal bacteria, viruses, and fungi. Therefore, the intestinal immune system is constantly…”
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Molecular and functional heterogeneity of IL-10-producing CD4+ T cells by Brockmann, Leonie, Soukou, Shiwa, Steglich, Babett, Czarnewski, Paulo, Zhao, Lilan, Wende, Sandra, Bedke, Tanja, Ergen, Can, Manthey, Carolin, Agalioti, Theodora, Geffken, Maria, Seiz, Oliver, Parigi, Sara M., Sorini, Chiara, Geginat, Jens, Fujio, Keishi, Jacobs, Thomas, Roesch, Thomas, Izbicki, Jacob R., Lohse, Ansgar W., Flavell, Richard A., Krebs, Christian, Gustafsson, Jan-Ake, Antonson, Per, Roncarolo, Maria Grazia, Villablanca, Eduardo J., Gagliani, Nicola, Huber, Samuel

“…IL-10 is a prototypical anti-inflammatory cytokine, which is fundamental to the maintenance of immune homeostasis, especially in the intestine. There is an…”
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The induction and function of the anti-inflammatory fate of TH17 cells by Xu, Hao, Agalioti, Theodora, Zhao, Jun, Steglich, Babett, Wahib, Ramez, Vesely, Maria Carolina Amezcua, Bielecki, Piotr, Bailis, Will, Jackson, Ruaidhri, Perez, Daniel, Izbicki, Jakob, Licona-Limón, Paula, Kaartinen, Vesa, Geginat, Jens, Esplugues, Enric, Tolosa, Eva, Huber, Samuel, Flavell, Richard A., Gagliani, Nicola

“…T H 17 cells exemplify environmental immune adaptation: they can acquire both a pathogenic and an anti-inflammatory fate. However, it is not known whether the…”
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Molecular consequences of SARS-CoV-2 liver tropism by Wanner, Nicola, Andrieux, Geoffroy, Badia-i-Mompel, Pau, Edler, Carolin, Pfefferle, Susanne, Lindenmeyer, Maja T., Schmidt-Lauber, Christian, Czogalla, Jan, Wong, Milagros N., Okabayashi, Yusuke, Braun, Fabian, Lütgehetmann, Marc, Meister, Elisabeth, Lu, Shun, Noriega, Maria L. M., Günther, Thomas, Grundhoff, Adam, Fischer, Nicole, Bräuninger, Hanna, Lindner, Diana, Westermann, Dirk, Haas, Fabian, Roedl, Kevin, Kluge, Stefan, Addo, Marylyn M., Huber, Samuel, Lohse, Ansgar W., Reiser, Jochen, Ondruschka, Benjamin, Sperhake, Jan P., Saez-Rodriguez, Julio, Boerries, Melanie, Hayek, Salim S., Aepfelbacher, Martin, Scaturro, Pietro, Puelles, Victor G., Huber, Tobias B.

“…Extrapulmonary manifestations of COVID-19 have gained attention due to their links to clinical outcomes and their potential long-term sequelae 1 . Severe acute…”
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