Search Results - "Huber, Peter"
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Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS+/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy
Published in Cancer cell (11-11-2013)“…Inefficient T cell migration is a major limitation of cancer immunotherapy. Targeted activation of the tumor microenvironment may overcome this barrier. We…”
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Fibroblast Activation Protein-Specific PET/CT Imaging in Fibrotic Interstitial Lung Diseases and Lung Cancer: A Translational Exploratory Study
Published in Journal of Nuclear Medicine (01-01-2022)“…Interstitial lung diseases (ILDs) comprise over 200 parenchymal lung disorders. Among them, fibrosing ILDs, especially idiopathic pulmonary fibrosis, are…”
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Mesenchymal stem cells – A new hope for radiotherapy-induced tissue damage?
Published in Cancer letters (01-10-2015)“…Highlights • Normal tissue toxicity often limits the applicable radiation dose to the tumor. • Mesenchymal stem cells can aid repair of various…”
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Brain tumour cells interconnect to a functional and resistant network
Published in Nature (London) (03-12-2015)“…Astrocytic brain tumours, including glioblastomas, are incurable neoplasms characterized by diffusely infiltrative growth. Here we show that many tumour cells…”
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Clinical and future applications of high intensity focused ultrasound in cancer
Published in Cancer treatment reviews (01-08-2012)“…Abstract High intensity focused ultrasound (HIFU) or focused ultrasound (FUS) is a promising modality to treat tumors in a complete, non invasive fashion where…”
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Tweety-Homolog 1 Drives Brain Colonization of Gliomas
Published in The Journal of neuroscience (19-07-2017)“…Early and progressive colonization of the healthy brain is one hallmark of diffuse gliomas, including glioblastomas. We recently discovered ultralong (>10 to…”
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Effects of CTGF Blockade on Attenuation and Reversal of Radiation-Induced Pulmonary Fibrosis
Published in JNCI : Journal of the National Cancer Institute (01-08-2017)“…Radiotherapy is a mainstay for the treatment of lung cancer that can induce pneumonitis or pulmonary fibrosis. The matricellular protein connective tissue…”
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IDH-wildtype glioblastomas and grade III/IV IDH-mutant gliomas show elevated tracer uptake in fibroblast activation protein–specific PET/CT
Published in European journal of nuclear medicine and molecular imaging (01-11-2019)“…Purpose Targeting fibroblast activation protein (FAP) is a new diagnostic approach allowing the visualization of tumor stroma. Here, we applied FAP-specific…”
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The Role of Migration as Adjustment Mechanism in the Crisis and EMU
Published in Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis (01-01-2018)“…Using ELFS data from 2004 to 2014 we analyse labour migration as an adjustment mechanism to asymmetric regional labour demand shocks shortly before, during and…”
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MicroRNA expression after ionizing radiation in human endothelial cells
Published in Radiation oncology (London, England) (26-03-2010)“…Endothelial cells (EC) in tumor and normal tissue constitute critical radiotherapy targets. MicroRNAs have emerged as master switchers of the cellular…”
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Hypofractionated Radiotherapy With Simultaneous-integrated Boost After Breast-conserving Surgery Compared to Standard Boost-applications Using Helical Tomotherapy With TomoEdge
Published in Anticancer research (01-04-2021)“…This comparative plan study examines a range of boost-radiation methods in adjuvant radiotherapy of breast cancer using helical intensity-modulated…”
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Helical Tomotherapy of Lymph Node-negative Early-stage Breast Cancer After Breast-conserving Surgery: Long-term Results
Published in Anticancer research (01-05-2023)“…Adjuvant radiotherapy is an integral part of the interdisciplinary curative treatment of breast cancer. We aimed to examine the long-term clinical results of…”
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The current understanding of mesenchymal stem cells as potential attenuators of chemotherapy‐induced toxicity
Published in International journal of cancer (01-12-2018)“…Chemotherapeutic agents are part of the standard treatment algorithms for many malignancies; however, their application and dosage are limited by their toxic…”
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Blockade of TGF-β Signaling by the TGFβR-I Kinase Inhibitor LY2109761 Enhances Radiation Response and Prolongs Survival in Glioblastoma
Published in Cancer research (Chicago, Ill.) (01-12-2011)“…Glioblastoma multiforme (GBM) is a highly aggressive primary brain tumor that tends to be resistant to the ionizing radiotherapy used to treat it. Because…”
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Mesenchymal Stem Cells Retain Their Defining Stem Cell Characteristics After Exposure to Ionizing Radiation
Published in International journal of radiation oncology, biology, physics (01-12-2013)“…Purpose Mesenchymal stem cells (MSCs) have the ability to migrate to lesion sites and undergo differentiation into functional tissues. Although this function…”
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Radio-resistant mesenchymal stem cells: mechanisms of resistance and potential implications for the clinic
Published in Oncotarget (14-08-2015)“…Mesenchymal stem cells (MSCs) comprise a heterogeneous population of multipotent stromal cells and can be isolated from various tissues and organs. Due to…”
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DNA damage response of clinical carbon ion versus photon radiation in human glioblastoma cells
Published in Radiotherapy and oncology (01-04-2019)“…•Carbon ions induced more severe DNA double-strand breaks than photons.•Carbon ion-induced double-strand breaks were repaired slower and less…”
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Combined intensity‐modulated radiotherapy plus raster‐scanned carbon ion boost for advanced adenoid cystic carcinoma of the head and neck results in superior locoregional control and overall survival
Published in Cancer (01-09-2015)“…BACKGROUND Local control in patients with adenoid cystic carcinoma (ACC) of the head and neck remains a challenge because of the relative radioresistance of…”
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Primary and adjuvant intensity-modulated radiotherapy in oropharyngeal carcinoma patients from a single institution
Published in Journal of cancer research and therapeutics (01-01-2024)“…To retrospectively access outcome, adverse events and prognostic factors in oropharyngeal carcinoma (OPC) patients treated with intensity-modulated…”
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Repetitive Early 68Ga-FAPI PET Acquisition Comparing 68Ga-FAPI-02, 68Ga-FAPI-46, and 68Ga-FAPI-74: Methodologic and Diagnostic Implications for Malignant, Inflammatory/Reactive, and Degenerative Lesions
Published in The Journal of nuclear medicine (1978) (01-12-2022)“…68Ga-labeled fibroblast activation protein (FAP) inhibitor (68Ga-FAPI) PET targets 68Ga-FAPI–positive activated fibroblasts and is a promising imaging…”
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