Search Results - "Huber, K"
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Review: Welfare in farm animals from an animal-centred point of view
Published in Animal (Cambridge, England) (01-10-2024)“…•Large-scale animal protein production is needed to ensure human nutritional needs.•Genetic selection and management for early high production is challenging…”
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Invited review: resource allocation mismatch as pathway to disproportionate growth in farm animals – prerequisite for a disturbed health
Published in Animal (Cambridge, England) (01-03-2018)“…The availability of resources including energy, nutrients and (developmental) time has a crucial impact on productivity of farm animals. Availability of energy…”
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Quantifying Target Occupancy of Small Molecules Within Living Cells
Published in Annual review of biochemistry (20-06-2020)“…The binding affinity and kinetics of target engagement are fundamental to establishing structure-activity relationships (SARs) for prospective therapeutic…”
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Covid-19 shelter-at-home and work, lifestyle and well-being in desk workers
Published in Occupational medicine (Oxford) (09-04-2021)“…Emerging cross-sectional reports find that the COVID-19 pandemic and related social restrictions negatively affect lifestyle behaviours and mental health in…”
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Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche
Published in Nature (London) (01-07-2018)“…Epithelial surfaces form critical barriers to the outside world and are continuously renewed by adult stem cells 1 . Whereas dynamics of epithelial stem cells…”
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Formation of Olivine Veins by Reactive Fluid Flow in a Dehydrating Serpentinite
Published in Geochemistry, geophysics, geosystems : G3 (01-06-2022)“…Many exposed high‐pressure meta‐serpentinites comprise a channelized network of olivine‐rich veins that formed during dehydration at depth and allowed the…”
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Detecting Planets Around Very Low Mass Stars with the Radial Velocity Method
Published in The Astrophysical journal (10-02-2010)“…The detection of planets around very low-mass stars with the radial velocity (RV) method is hampered by the fact that these stars are very faint at optical…”
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The hybrid number of a ploidy profile
Published in Journal of mathematical biology (01-09-2022)“…Polyploidization, whereby an organism inherits multiple copies of the genome of their parents, is an important evolutionary event that has been observed in…”
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Cardiovascular disease risk reduction by raising HDL cholesterol – current therapies and future opportunities
Published in British journal of pharmacology (01-11-2012)“…Since the first discovery of an inverse correlation between high‐density lipoprotein‐cholesterol (HDL‐C) levels and coronary heart disease in the 1950s the…”
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Neutrophil-related factors as biomarkers in EAE and MS
Published in The Journal of experimental medicine (12-01-2015)“…A major function of T helper (Th) 17 cells is to induce the production of factors that activate and mobilize neutrophils. Although Th17 cells have been…”
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2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC)
Published in European heart journal (14-01-2016)Get full text
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Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing
Published in Nature communications (05-02-2020)“…Heterotopic ossification (HO) is an aberrant regenerative process with ectopic bone induction in response to musculoskeletal trauma, in which mesenchymal stem…”
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Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site
Published in Leukemia (01-11-2017)“…The BCR/ABL1 inhibitor Nilotinib is increasingly used to treat patients with chronic myeloid leukemia (CML). Although otherwise well-tolerated, Nilotinib has…”
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A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis
Published in Cell death & disease (01-05-2015)“…Necroptosis is a form of regulated necrotic cell death mediated by receptor-interacting serine/threonine-protein kinase 1 (RIPK1) and RIPK3. Necroptotic cell…”
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Autopolyploidy, Allopolyploidy, and Phylogenetic Networks with Horizontal Arcs
Published in Bulletin of mathematical biology (01-05-2023)“…Polyploidization is an evolutionary process by which a species acquires multiple copies of its complete set of chromosomes. The reticulate nature of the signal…”
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Tree-Based Unrooted Phylogenetic Networks
Published in Bulletin of mathematical biology (01-02-2018)“…Phylogenetic networks are a generalization of phylogenetic trees that are used to represent non-tree-like evolutionary histories that arise in organisms such…”
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Blood and liver telomere length, mitochondrial DNA copy number, and hepatic gene expression of mitochondrial dynamics in mid-lactation cows supplemented with l-carnitine under systemic inflammation
Published in Journal of dairy science (01-12-2023)“…The current study was conducted to examine the effect of l-carnitine (LC) supplementation on telomere length and mitochondrial DNA copy number (mtDNAcn) per…”
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Comparison of a modified 2-step insulin response test performed with porcine zinc insulin and an oral glucose test to detect hyperinsulinemic Icelandic horses
Published in The veterinary journal (1997) (01-08-2023)“…Both, oral and intravenous (IV) testing protocols, are recommended and still used to detect insulin dysregulation (ID) in equids. However, IV tests mainly…”
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Differential in vivo activation of monocyte subsets during low-grade inflammation through experimental endotoxemia in humans
Published in Scientific reports (22-07-2016)“…Human monocytes are a heterogeneous cell population, which can be divided into a classical (CD14++CD16−), a non-classical (CD14+CD16+) and an intermediate…”
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