Search Results - "Hubbard, D"
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Indole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation
Published in Drug metabolism and disposition (01-10-2015)“…The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor recognized for its role in xenobiotic metabolism. The physiologic function of…”
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Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles
Published in Scientific reports (03-08-2015)“…Ligand activation of the aryl hydrocarbon (AHR) has profound effects upon the immunological status of the gastrointestinal tract, establishing and maintaining…”
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3
Understanding chemical reaction mechanisms in ionic liquids: successes and challenges
Published in Chemical Society reviews (01-01-2011)“…The focus of this article is an examination of chemical reaction mechanisms in ionic liquids. These mechanisms are compared with those pertaining to the same…”
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Persistent Organic Pollutants Modify Gut Microbiota-Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation
Published in Environmental health perspectives (01-07-2015)“…Alteration of the gut microbiota through diet and environmental contaminants may disturb physiological homeostasis, leading to various diseases including…”
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Poly(amido amine) dendrimers as absorption enhancers for oral delivery of camptothecin
Published in International journal of pharmaceutics (01-11-2013)“…Oral delivery of camptothecin has a treatment advantage but is limited by low bioavailability and gastrointestinal toxicity. Poly(amido amine) or PAMAM…”
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6
Long-term potentiation expands information content of hippocampal dentate gyrus synapses
Published in Proceedings of the National Academy of Sciences - PNAS (06-03-2018)“…An approach combining signal detection theory and precise 3D reconstructions from serial section electron microscopy (3DEM) was used to investigate synaptic…”
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Identifying the essential knowledge and skills for Neonatal-Perinatal Medicine: a systematic analysis of practice
Published in Journal of perinatology (01-09-2022)“…The knowledge and skills expected for board certification in Neonatal-Perinatal Medicine (NPM) should reflect the clinical practice of neonatology. First, a…”
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Consensus guidelines for diagnosis and management of anemia in epidermolysis bullosa
Published in Orphanet journal of rare diseases (23-02-2023)“…Anemia is a common complication of severe forms of epidermolysis bullosa (EB). To date, there are no guidelines outlining best clinical practices to manage…”
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Evaluating the influence of marine protected areas on surf zone fish
Published in Conservation biology (21-05-2024)“…Marine protected areas (MPAs) globally serve conservation and fisheries management goals, generating positive effects in some marine ecosystems. Surf zones and…”
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10
Global diversity of mayflies (Ephemeroptera, Insecta) in freshwater
Published in Hydrobiologia (01-01-2008)“…The extant global Ephemeroptera fauna is represented by over 3,000 described species in 42 families and more than 400 genera. The highest generic diversity…”
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Dietary broccoli impacts microbial community structure and attenuates chemically induced colitis in mice in an Ah receptor dependent manner
Published in Journal of functional foods (01-10-2017)“…•Dietary broccoli activates the colonic AHR the high ligand affinity AHRb in mice.•Dietary broccoli influences the composition of the mouse cecal…”
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12
Local extirpations and regional declines of endemic upper beach invertebrates in southern California
Published in Estuarine, coastal and shelf science (05-10-2014)“…Along the world's highly valued and populous coastlines, the upper intertidal zones of sandy beach ecosystems and the biodiversity that these zones support are…”
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Prospective cohort study of retinal vessel diameters and risk of hypertension
Published in BMJ (10-07-2004)“…Abstract Objective To examine the relation between diameters of the retinal arterioles and 10 year incidence of hypertension. Design Population based…”
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14
Diagnosis of Agglomeration and Crystallinity of Active Pharmaceutical Ingredients in Over the Counter Headache Medication by Electrospray Laser Desorption Ionization Mass Spectrometry Imaging
Published in Molecules (Basel, Switzerland) (25-01-2021)“…Agglomeration of active pharmaceutical ingredients (API) in tablets can lead to decreased bioavailability in some enabling formulations. In a previous study,…”
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Retinal arteriolar diameter and Risk for hypertension
Published in Annals of internal medicine (17-02-2004)“…Narrowing of the small arterioles has been hypothesized to contribute to the pathogenesis of hypertension, but prospective clinical data are lacking. To…”
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Retinal microvascular abnormalities and incident stroke : The atherosclerosis risk in communities study
Published in The Lancet (British edition) (06-10-2001)“…Retinal microvascular abnormalities reflect damage from hypertension and other vascular processes. We examined the relation of such abnormalities to incident…”
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Retinal Vessel Diameters and Their Associations with Age and Blood Pressure
Published in Investigative ophthalmology & visual science (01-11-2003)“…To describe the cross-sectional relationship between retinal arteriolar and venular diameters with age and blood pressure. A population-based study was…”
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Methods for evaluation of retinal microvascular abnormalities associated with hypertension/sclerosis in the Atherosclerosis Risk in Communities Study
Published in Ophthalmology (Rochester, Minn.) (01-12-1999)“…To develop protocols to photograph and evaluate retinal vascular abnormalities in the Atherosclerosis Risk in Communities (ARIC) Study; to test reproducibility…”
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Associations between the Metabolic Syndrome and Retinal Microvascular Signs: The Atherosclerosis Risk in Communities Study
Published in Investigative ophthalmology & visual science (01-09-2004)“…To examine the cross-sectional relationship of the metabolic syndrome (hypertension, hyperglycemia, central obesity, and dyslipidemia) and retinal…”
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Multicomponent Cycloadditions: The Four-Component [5+1+2+1] Cycloaddition of Vinylcyclopropanes, Alkynes, and CO
Published in Journal of the American Chemical Society (09-03-2005)“…Prompted by the view that intermediates of transition metal-catalyzed reactions could be intercepted by one or more additional components, studies in our…”
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