Search Results - "Huang, Zunnan"

Marine Natural Products in Clinical Use by Haque, Neshatul, Parveen, Sana, Tang, Tingting, Wei, Jiaen, Huang, Zunnan

“…Marine natural products are potent and promising sources of drugs among other natural products of plant, animal, and microbial origin. To date, 20 drugs from…”
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In Silico Methods for Identification of Potential Active Sites of Therapeutic Targets by Liao, Jianbo, Wang, Qinyu, Wu, Fengxu, Huang, Zunnan

“…Target identification is an important step in drug discovery, and computer-aided drug target identification methods are attracting more attention compared with…”
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Role of Computer-Aided Drug Design in Drug Development by Gu, Ruoxu, Wu, Fengxu, Huang, Zunnan

“…The introduction of computational techniques to pharmaceutical chemistry and molecular biology in the 20th century has changed the way people develop drugs…”
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Long non-coding RNA: a new player in cancer by Zhang, Hua, Chen, Zhenhua, Wang, Xinxin, Huang, Zunnan, He, Zhiwei, Chen, Yueqin

“…Emerging evidence showed that long non-coding RNAs (lncRNAs) play important roles in a wide range of biological processes and dysregulated lncRNAs are involved…”
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From Levinthal's Paradox to the Effects of Cell Environmental Perturbation on Protein Folding by Zeng, Juan, Huang, Zunnan

“…The rapidly increasing number of known protein sequences calls for more efficient methods to predict the Three-Dimensional (3D) structures of proteins, thus…”
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Marine compounds targeting the PI3K/Akt signaling pathway in cancer therapy by Wei, Jiaen, Gou, Zhanping, Wen, Ying, Luo, Qiaohong, Huang, Zunnan

“…The PI3K/Akt signaling pathway plays an important role in the development of cancer and is considered a therapeutic target of many cancer therapies. Bioactive…”
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Computational Approaches in Preclinical Studies on Drug Discovery and Development by Wu, Fengxu, Zhou, Yuquan, Li, Langhui, Shen, Xianhuan, Chen, Ganying, Wang, Xiaoqing, Liang, Xianyang, Tan, Mengyuan, Huang, Zunnan

“…Because undesirable pharmacokinetics and toxicity are significant reasons for the failure of drug development in the costly late stage, it has been widely…”
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Identification of Prognostic miRNA Signature and Lymph Node Metastasis-Related Key Genes in Cervical Cancer by Chen, Shuoling, Gao, Chang, Wu, Yangyuan, Huang, Zunnan

“…miRNAs and genes can serve as biomarkers for the prognosis and therapy of cervical tumors whose metastasis into lymph nodes is closely associated with disease…”
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MAPK signaling pathway-targeted marine compounds in cancer therapy by Wei, Jiaen, Liu, Ruining, Hu, Xiyun, Liang, Tingen, Zhou, Zhiran, Huang, Zunnan

“…Purpose This paper reviews marine compounds that target the mitogen-activated protein kinase (MAPK) signaling pathway and their main sources, chemical…”
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Inexpensive Method for Selecting Receptor Structures for Virtual Screening by Huang, Zunnan, Wong, Chung F

“…This article introduces a screening performance index (SPI) to help select from a number of experimental structures one or a few that are more likely to…”
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Identification of Hypoxia-Related Prognostic Signature and Competing Endogenous RNA Regulatory Axes in Hepatocellular Carcinoma by Tang, Yulai, Zhang, Hua, Chen, Lingli, Zhang, Taomin, Xu, Na, Huang, Zunnan

“…Hepatocellular carcinoma (HCC) is a common type of liver cancer and one of the highly lethal diseases worldwide. Hypoxia plays an important role in the…”
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Editorial: Antioxidants and inflammatory immune-related diseases by Xu, Pengfei, Huang, Zunnan, Xu, Yanyong, Liu, Huanxiang, Liu, Yuyu, Wang, Ling

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Correction: Haque et al. Marine Natural Products in Clinical Use. Mar. Drugs 2022, 20, 528 by Haque, Neshatul, Parveen, Sana, Tang, Tingting, Wei, Jiaen, Huang, Zunnan

“…The authors would like to make corrections to a recently published paper [...]…”
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Bioinformatics Analysis of Prognostic miRNA Signature and Potential Critical Genes in Colon Cancer by Chen, Weigang, Gao, Chang, Liu, Yong, Wen, Ying, Hong, Xiaoling, Huang, Zunnan

“…This study aims to lay a foundation for studying the regulation of microRNAs (miRNAs) in colon cancer by applying bioinformatics methods to identify miRNAs and…”
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Assessment of SWI/SNF chromatin remodeling complex related genes as potential biomarkers and therapeutic targets in pan-cancer by Zhuang, Kai, Wang, Lishan, Lu, Chengyu, Liu, Zhiping, Yang, Dongli, Zhong, Hao, Zou, Jiami, Fahira, Aamir, Wang, Jiaojiao, Huang, Zunnan

“…Recent research has uncovered a surprisingly high occurrence of aberrant expression and mutations in the genes that encode subunits of the SWI/SNF…”
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Reverse Screening Methods to Search for the Protein Targets of Chemopreventive Compounds by Huang, Hongbin, Zhang, Guigui, Zhou, Yuquan, Lin, Chenru, Chen, Suling, Lin, Yutong, Mai, Shangkang, Huang, Zunnan

“…This article is a systematic review of reverse screening methods used to search for the protein targets of chemopreventive compounds or drugs. Typical…”
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Lysosome-targeted ruthenium(II) complex encapsulated with pluronic® F-127 induces oncosis in A549 cells by Pan, Nanlian, Zhang, Yuqing, Huang, Minying, Liang, Zhijun, Gong, Yao, Chen, Xide, Li, Yuling, Wu, Ciling, Huang, Zunnan, Sun, Jing

“…Transition metal complexes with characteristics of unique packaging in nanoparticles and remarkable cancer cell cytotoxicity have emerged as potential…”
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Development and Application of Computational Methods in Biology and Medicine by Huang, Zunnan, Gu, Ruo-Xu

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Advanced stratification analyses in molecular association meta-analysis: methodology and application by Lin, Shuhuang, Ma, Yukun, Huang, Zunnan

“…Stratification analyses have been widely utilized in molecular association meta-analyses to estimate the interaction between genetic and environmental factors…”
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Role of microRNA‑33a in malignant cells (Review) by Gao, Chang, Wei, Jiaen, Tang, Tingting, Huang, Zunnan

“…Cancer causes most of the mortality and morbidity worldwide, with a significant increase in incidence during recent years. MicroRNAs (miRNAs/miRs) are…”
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