Search Results - "Huang, Zhenghui"
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Genome survey sequencing and characterization of simple sequence repeat (SSR) markers in Platostoma palustre (Blume) A.J.Paton (Chinese mesona)
Published in Scientific reports (10-01-2022)“…Platostoma palustre (Blume) A.J.Paton is an annual herbaceous persistent plant of the Labiatae family. However, there is a lack of genomic data for this plant,…”
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2
Point-of-care test system for detection of immunoglobulin-G and -M against nucleocapsid protein and spike glycoprotein of SARS-CoV-2
Published in Sensors and actuators. B, Chemical (15-03-2021)“…[Display omitted] •A POCT system has been developed for objectively and accurately detecting IgG and IgM against SARS-CoV-2.•The levels of IgG and IgM in the…”
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3
Bortezomib restrains M2 polarization and reduces CXCL16-associated CXCR6 + CD4 T cell chemotaxis in bleomycin-induced pulmonary fibrosis
Published in Molecular medicine (Cambridge, Mass.) (24-05-2024)“…The development of pulmonary fibrosis involves a cascade of events, in which inflammation mediated by immune cells plays a pivotal role. Chemotherapeutic drugs…”
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4
Identification and validation of a hypoxia-immune signature for overall survival prediction in lung adenocarcinoma
Published in Frontiers in genetics (03-10-2022)“…Objective: The interaction between immunity and hypoxia in tumor microenvironment (TME) has clinical significance, and this study aims to explore…”
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5
PfAP2-G2 Is Associated to Production and Maturation of Gametocytes in Plasmodium falciparum via Regulating the Expression of PfMDV-1
Published in Frontiers in microbiology (18-01-2021)“…Gametocyte is the sole form of the which is transmissible to the mosquito vector. Here, we report that an Apicomplexan Apetala2 (ApiAP2) family transcription…”
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6
A natural symbiotic bacterium drives mosquito refractoriness to Plasmodium infection via secretion of an antimalarial lipase
Published in Nature microbiology (01-06-2021)“…The stalling global progress in the fight against malaria prompts the urgent need to develop new intervention strategies. Whilst engineered symbiotic bacteria…”
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Identification of Genetic Loci for Sugarcane Leaf Angle at Different Developmental Stages by Genome-Wide Association Study
Published in Frontiers in plant science (27-05-2022)“…Sugarcane ( spp.) is an efficient crop mainly used for sugar and bioethanol production. High yield and high sucrose of sugarcane are always the fundamental…”
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Effect of Baihe Gujin decoction combined with Shengmai powder on the expression of IL-1β and IL-1Ra in peripheral blood CD14+ monocytes from patients with pulmonary tuberculosis
Published in Cellular and Molecular Biology (28-02-2022)“…This experiment was conducted to investigate the effect of taking Baihe Gujin decoction combined with Shengmai powder on IL-1β and IL-1Ra expression in…”
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9
Efficacy and safety of TCMs with anti-inflammatory effect in patients with rheumatoid arthritis: A network meta-analysis
Published in Frontiers in immunology (08-03-2023)“…Traditional Chinese medicines (TCMs), such as Tripterygium wilfordii Hook F (TwHF), Glycyrrhiza uralensis, Caulis sinomenii and others have anti-inflammatory…”
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10
The Zscan4-Tet2 Transcription Nexus Regulates Metabolic Rewiring and Enhances Proteostasis to Promote Reprogramming
Published in Cell reports (Cambridge) (14-07-2020)“…Evolutionarily conserved SCAN (named after SRE-ZBP, CTfin51, AW-1, and Number 18 cDNA)-domain-containing zinc finger transcription factors (ZSCAN) have been…”
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11
A novel multistage antiplasmodial inhibitor targeting Plasmodium falciparum histone deacetylase 1
Published in Cell discovery (11-12-2020)“…Although artemisinin combination therapies have succeeded in reducing the global burden of malaria, multidrug resistance of the deadliest malaria parasite,…”
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12
Repurposing of antitumor drug candidate Quisinostat lead to novel spirocyclic antimalarial agents
Published in Chinese chemical letters (01-05-2021)“…By repurposing clinical phase Ⅱ antitumor drug candidate Quisinostat, we designed and synthesized 30 novel spirocyclic linker derivatives, and found an optimal…”
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13
Genome Survey Sequence and the Development of Simple Sequence Repeat (SSR) Markers in Erianthus arundinaceus
Published in Sugar tech : an international journal of sugar crops & related industries (01-02-2021)“…Erianthus arundinaceus possesses high biomass, vigor, ratoonability and resistance to biotic and abiotic stresses and is considered to be an ideal species for…”
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14
The effect of vascular risk factor burden on the severity of COVID-19 illness, a retrospective cohort study
Published in Respiratory research (21-09-2020)“…Patients with cardiovascular comorbidities are at high risk of poor outcome from COVID-19. However, how the burden (number) of vascular risk factors influences…”
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15
Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors
Published in Communications biology (18-06-2024)“…Aminoacyl-tRNA synthetases (aaRSs) play a central role in the translation of genetic code, serving as attractive drug targets. Within this family, the…”
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Design and synthesis of novel hydroxamic acid derivatives based on quisinostat as promising antimalarial agents with improved safety
Published in Acta Materia Medica (01-05-2022)“…In our previous work, the clinical phase II HDAC inhibitor quisinostat was identified as a promising antimalarial agent through a drug repurposing strategy,…”
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Design, synthesis, and biological evaluation of multiple targeting antimalarials
Published in Acta pharmaceutica Sinica. B (01-09-2021)“…Malaria still threatens global health seriously today. While the current discoveries of antimalarials are almost totally focused on single mode-of-action…”
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18
Tripchlorolide induces cell death in lung cancer cells by autophagy
Published in International journal of oncology (01-04-2012)“…It has been demonstrated that triptolide inhibits the growth of several types of cancer cells in vitro and prevents tumor growth in vivo by inducing apoptosis…”
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6-month consequences of COVID-19 in patients discharged from hospital: a cohort study
Published in The Lancet (British edition) (16-01-2021)“…The long-term health consequences of COVID-19 remain largely unclear. The aim of this study was to describe the long-term health consequences of patients with…”
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Coordinated Optimization of Repair Scheduling and Service Restoration for Distribution Network Considering the Damaged Roads
Published in IEEE transactions on industry applications (01-07-2024)“…Extreme natural disasters can cause catastrophic damages to both the equipment of the distribution network and road segments of the transportation network,…”
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