Search Results - "Huang, Zhaoqin"
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Predictive biomarkers in PD-1/PD-L1 checkpoint blockade immunotherapy
Published in Cancer treatment reviews (01-12-2015)“…Highlights • PD-1/PD-L1 blockades present a new paradigm shift in immunotherapy for cancer. • It is crucial to identify a biomarker predicting the response to…”
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SBRT combined with PD-1/PD-L1 inhibitors in NSCLC treatment: a focus on the mechanisms, advances, and future challenges
Published in Journal of hematology and oncology (28-07-2020)“…Immune checkpoint inhibitors targeting programmed cell death 1 (PD-1), programmed cell death ligand-1 (PD-L1), and others have shown potent clinical efficacy…”
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Numerical simulation of hydro-mechanical coupling in fractured vuggy porous media using the equivalent continuum model and embedded discrete fracture model
Published in Advances in water resources (01-04-2019)“…•An efficient numerical model is proposed to simulate the hydro-mechanical coupling in the fractured vuggy porous media containing multi-scale fractures and…”
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Coupled numerical approach combining X-FEM and the embedded discrete fracture method for the fluid-driven fracture propagation process in porous media
Published in International journal of rock mechanics and mining sciences (Oxford, England : 1997) (01-06-2020)“…A coupled simulation strategy combining the embedded discrete fracture method (EDFM) and the extended finite element method (X-FEM) is developed to simulate…”
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Looking for the Optimal PD-1/PD-L1 Inhibitor in Cancer Treatment: A Comparison in Basic Structure, Function, and Clinical Practice
Published in Frontiers in immunology (29-05-2020)“…Programmed cell death protein-1/ligand 1 (PD-1/L1) targeted immune checkpoint inhibitors have become the focus of tumor treatment due to their promising…”
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A Comparison of Mixed Multiscale Finite Element Methods for Multiphase Transport in Highly Heterogeneous Media
Published in Water resources research (01-05-2021)“…In this study, we systemically review and compare two mixed multiscale finite element methods (MMsFEM) for multiphase transport in highly heterogeneous media…”
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Stress sensitivity analysis of vuggy porous media based on two-scale fractal theory
Published in Scientific reports (05-09-2024)“…Interparticle pore space and vugs are two different scales of pore space in vuggy porous media. Vuggy porous media widely exists in carbonate reservoirs, and…”
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Impact of fracture shear dilation on long-term heat extraction in Enhanced Geothermal Systems: Insights from a fully-coupled thermo-hydro-mechanical simulation
Published in Geothermics (01-11-2021)“…•An improved thermo-hydro-mechanical coupling model is developed.•Effects of shear dilation and thermal stress on heat extraction are investigated.•Effects of…”
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Parameter Effect Analysis of Non-Darcy Flow and a Method for Choosing a Fluid Flow Equation in Fractured Karstic Carbonate Reservoirs
Published in Energies (Basel) (01-05-2022)“…Fractured karstic carbonate reservoirs have obvious multi-scale characteristics and severe heterogeneity due to the development of abundant karst caves and…”
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The prognostic value of TCF1+CD8+T in primary small cell carcinoma of the esophagus
Published in Cancer science (01-12-2021)“…TCF1+CD8+T cells are reported to exhibit stem‐like properties with the ability to self‐renew and differentiate into terminal effector T cells (TCF1‐CD8+T…”
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Simulating two-phase flow and geomechanical deformation in fractured karst reservoirs based on a coupled hydro-mechanical model
Published in International journal of rock mechanics and mining sciences (Oxford, England : 1997) (01-01-2021)“…Two-phase flow in fractured and karstified porous media subject to coupled hydro-mechanical conditions is an important issue for oil recovery in carbonate…”
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Analysis of fracture propagation and shale gas production by intensive volume fracturing
Published in Applied mathematics and mechanics (01-08-2023)“…This paper presents an integrated study from fracture propagation modeling to gas flow modeling and a correlation analysis to explore the key controlling…”
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A New Non-Darcy Flow Model for Low-Velocity Multiphase Flow in Tight Reservoirs
Published in Transport in porous media (01-04-2017)“…The pore and pore-throat sizes of shale and tight rock formations are on the order of tens of nanometers. The fluid flow in such small pores is significantly…”
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Radiation Recall Pneumonitis Induced by Anti-PD-1 Blockade: A Case Report and Review of the Literature
Published in Frontiers in oncology (28-04-2020)“…Radiation recall pneumonitis (RRP) is an unpredictable but relatively severe subclinical radiation damage which occurs in the previously irradiated fields of…”
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Multiscale mimetic method for two-phase flow in fractured media using embedded discrete fracture model
Published in Advances in water resources (01-09-2017)“…•The presented multiscale method could avoid the complicated unstructured grid generation and computing process.•The presented formulation can generate…”
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Numerical Investigation of the Effect of Partially Propped Fracture Closure on Gas Production in Fractured Shale Reservoirs
Published in Energies (Basel) (13-10-2020)“…Nonuniform proppant distribution is fairly common in hydraulic fractures, and different closure behaviors of the propped and unpropped fractures have been…”
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Numerical Simulation of Well Type Optimization in Tridimensional Development of Multi-Layer Shale Gas Reservoir
Published in Energies (Basel) (01-09-2022)“…Aimed at the development of shale gas reservoirs with large reservoir thickness and multiple layers, this paper carried out a numerical simulation study on the…”
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Multiparametric MRI-based radiomic nomogram for predicting HER-2 2+ status of breast cancer
Published in Heliyon (15-05-2024)“…To explore the application of multiparametric MRI-based radiomic nomogram for assessing HER-2 2+ status of breast cancer (BC) Patients with pathology-proven…”
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A combined postoperative nomogram for survival prediction in clear cell renal carcinoma
Published in Abdominal radiology (New York) (2022)“…Purpose To investigate and validate the prognostic value of nomogram models for predicting disease-free survival (DFS) and overall survival (OS) in patients…”
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Modeling reactive flow dynamics of gelled acid in fracture-vuggy carbonates: a coupled thermal-hydrological-chemical simulation
Published in Science and technology for energy transition (01-01-2024)“…In engineering, gelled acids play a crucial role in facilitating reactive flow phenomena across diverse mediums. This study undertakes a comprehensive…”
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