Search Results - "Huang, Yanjuan"

Engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer by Huang, Yanjuan, Guan, Zilin, Dai, Xiuling, Shen, Yifeng, Wei, Qin, Ren, Lingling, Jiang, Jingwen, Xiao, Zhanghong, Jiang, Yali, Liu, Di, Huang, Zeqian, Xu, Xiaoyu, Luo, Yong, Zhao, Chunshun

“…Patients with primary and bone metastatic breast cancer have significantly reduced survival and life quality. Due to the poor drug delivery efficiency of…”
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Bisphosphonate-functionalized coordination polymer nanoparticles for the treatment of bone metastatic breast cancer by He, Yuanfeng, Huang, Yanjuan, Huang, Ziyuan, Jiang, Yali, Sun, Xiaoqi, Shen, Yifeng, Chu, Weijing, Zhao, Chunshun

“…Bone is the most common organ affected by metastatic breast cancer. Targeting cancers within the bone remains a great challenge due to the inefficient delivery…”
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Enhanced cancer therapy through synergetic photodynamic/immune checkpoint blockade mediated by a liposomal conjugate comprised of porphyrin and IDO inhibitor by Huang, Zeqian, Wei, Gaofei, Zeng, Zishan, Huang, Yanjuan, Huang, Liangfeng, Shen, Yifeng, Sun, Xiaoqi, Xu, Congjun, Zhao, Chunshun

“…Cancer metastases is still a hurdle for good prognosis and live quality of breast cancer patients. Treatment strategies that can inhibit metastatic cancer…”
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Clinical relevance of ARF/ARL family genes and oncogenic function of ARL4C in endometrial cancer by Zhang, Jiawen, Zhang, Qinyi, Sun, Cong, Huang, Yanjuan, Zhang, Jing, Wang, Qingying

“…•Genetic alterations and prognosis value of ARF/ARLs in endometrial cancer.•ARL4C functions as an oncogene via regulation of cell cycle and cell…”
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Bone-seeking nanoplatform co-delivering cisplatin and zoledronate for synergistic therapy of breast cancer bone metastasis and bone resorption by Huang, Yanjuan, Xiao, Zhanghong, Guan, Zilin, Zeng, Zishan, Shen, Yifeng, Xu, Xiaoyu, Zhao, Chunshun

“…The “vicious cycle” established between tumor growth and osteolysis aggravates the process of breast cancer bone metastasis, leading to life-threatening…”
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NIR-triggered thermo-responsive biodegradable hydrogel with combination of photothermal and thermodynamic therapy for hypoxic tumor by Sun, Xiaoqi, Liu, Di, Xu, Xiaoyu, Shen, Yifeng, Huang, Yanjuan, Zeng, Zishan, Xia, Meng, Zhao, Chunshun

“…Hypoxia is a typical feature of solid tumors, which highly limits the application of the oxygen-dependent therapy. Also, the dense and hyperbaric tumor tissues…”
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Effects of dextran sulfate sodium induced experimental colitis on cytochrome P450 activities in rat liver, kidney and intestine by Hu, Nan, Huang, Yanjuan, Gao, Xuejiao, Li, Sai, Yan, Zhixiang, Wei, Bin, Yan, Ru

“…Dextran sulfate sodium (DSS) induced experimental colitis presents a histologic resemblance to human ulcerative colitis (UC). Altered cytochrome P450s (CYPs)…”
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pH-activatable oxidative stress amplifying dissolving microneedles for combined chemo-photodynamic therapy of melanoma by Huang, Yanjuan, Lai, Hualu, Jiang, Jingwen, Xu, Xiaoyu, Zeng, Zishan, Ren, Lingling, Liu, Qiuxing, Chen, Meixu, Zhang, Tao, Ding, Xin, Zhao, Chunshun, Cui, Shengmiao

“…Photodynamic therapy (PDT)-mediated oxidation treatment is extremely attractive for skin melanoma ablation, but the strong hydrophobicity and poor tumor…”
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Preoperative screening for illicit drug use in patients undergoing emergency surgery: A prospective observational study by Li, Jingyi, Ma, He, Liao, Ren, Huang, Yanjuan, Chen, Guiyong

“…Knowledge of illicit drug users (IDUs) is important because of the comorbidity related to drug use. In this prospective, observational study, we screened 1007…”
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“NIR-triggered ROS storage” photodynamic intraocular implant for high-efficient and safe posterior capsular opacification prevention by Huang, Yanjuan, Zhang, Tao, Wei, Qin, Zeng, Zishan, Gong, Yujun, Xu, Xiaoyu, Chen, Meixu, Zhao, Chunshun

“…Posterior capsular opacification (PCO) is the leading cause of vision loss after cataract, mainly caused by the adhesion, proliferation and…”
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Intestinal Surgery Contributes to Acute Cerebellar Ataxia Through Gut Brain Axis by Yu, Jie, Fan, Yuanming, Wang, Li, Huang, Yanjuan, Xia, Jingyi, Ding, Le, Wu, Chun-Feng, Lu, Xiaopeng, Ma, Gaoxiang, Kim, Samuel, Zheng, Guo, Guo, Hu, Zhang, Gang

“…Introduction: Acute cerebellar ataxia (ACA) is the most common form of pediatric ataxia. Changes in gut flora can modulate the nervous system, influencing…”
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Harnessing Engineered Immune Cells and Bacteria as Drug Carriers for Cancer Immunotherapy by Jiang, Jingwen, Huang, Yanjuan, Zeng, Zishan, Zhao, Chunshun

“…Immunotherapy continues to be in the spotlight of oncology therapy research in the past few years and has been proven to be a promising option to modulate…”
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Tumor-targeted supramolecular catalytic nanoreactor for synergistic chemo/chemodynamic therapy via oxidative stress amplification and cascaded Fenton reaction by Xu, Xiaoyu, Zeng, Zishan, Chen, Jie, Huang, Binyao, Guan, Zilin, Huang, Yanjuan, Huang, Zeqian, Zhao, Chunshun

“…[Display omitted] •pH/redox dual-responsive targeted supramolecular catalytic nanoreactor was designed.•Prodrug Fc-CA combined ROS-generator with Fenton…”
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Three birds with one stone: A ferric pyrophosphate based nanoagent for synergetic NIR-triggered photo/chemodynamic therapy with glutathione depletion by Huang, Yanjuan, Jiang, Yali, Xiao, Zhanghong, Shen, Yifeng, Huang, Liangfeng, Xu, Xiaoyu, Wei, Gaofei, Xu, Congjun, Zhao, Chunshun

“…FeP-ZnPc combining the effect of enhancing ROS production and inhibiting ROS elimination effectively broken down the intracellular redox homeostasis. [Display…”
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Molten salt synthesis of nitrogen and oxygen enriched hierarchically porous carbons derived from biomass via rapid microwave carbonization for high voltage supercapacitors by Cheng, Yinfeng, Li, Baoqiang, Huang, Yanjuan, Wang, Yaming, Chen, Junchen, Wei, Daqing, Feng, Yujie, Jia, Dechang, Zhou, Yu

“…[Display omitted] •Nitrogen and oxygen enriched hierarchically porous carbons derived from carrot.•Rapid microwave carbonization of carrot powder is realized…”
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A light-triggered self-reinforced nanoagent for targeted chemo-photodynamic therapy of breast cancer bone metastases via ER stress and mitochondria mediated apoptotic pathways by Huang, Yanjuan, Xiao, Zhanghong, Guan, Zilin, Shen, Yifeng, Jiang, Yali, Xu, Xiaoyu, Huang, Zeqian, Zhao, Chunshun

“…Current therapeutic strategies for the treatment of bone metastases are often limited by the lack of selectivity, severe systemic toxicity and suboptimal…”
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Near-infrared light-triggered degradable hyaluronic acid hydrogel for on-demand drug release and combined chemo-photodynamic therapy by Xu, Xiaoyu, Zeng, Zishan, Huang, Zeqian, Sun, Yangwen, Huang, Yanjuan, Chen, Jie, Ye, Junxian, Yang, Haolan, Yang, Chanzhen, Zhao, Chunshun

“…[Display omitted] •Injectable and near-infrared light-triggered ROS-degradable hydrogel was developed.•The hydrogel was formed via the formation of dynamic…”
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Reactive oxygen species-activated self-amplifying prodrug nanoagent for tumor-specific Cu-chelate chemotherapy and cascaded photodynamic therapy by Chen, Jie, Tan, Xiaomin, Huang, Yanjuan, Xu, Congjun, Zeng, Zishan, Shan, Ting, Guan, Zilin, Xu, Xiaoyu, Huang, Zeqian, Zhao, Chunshun

“…Disulfiram (DSF), an effective FDA-approved anti-alcoholism drug, shows potent antitumor activity by producing Cu(DTC)2, a chelate of its metabolite…”
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A mitochondria-targeting ROS-activated nanoprodrug for self-augmented antitumor oxidation therapy by Zeng, Zishan, Luo, Yong, Xu, Xiaoyu, Shan, Ting, Chen, Meixu, Huang, Zeqian, Huang, Yanjuan, Zhao, Chunshun

“…Mitochondrion is an ideal target for amplifying ROS attack in antitumor treatment. Benefiting from distinctive properties of mitochondria, the precise delivery…”
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Calcium phosphate nanoparticles functionalized with alendronate-conjugated polyethylene glycol (PEG) for the treatment of bone metastasis by Chu, Weijing, Huang, Yanjuan, Yang, Chanzhen, Liao, Yunhui, Zhang, Xuefei, Yan, Mina, Cui, Shengmiao, Zhao, Chunshun

“…[Display omitted] Because of the peculiarity of the bone microstructure, the uptake of chemotherapeutics often happens at non-targeted sites, which induces…”
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