Search Results - "Huang, Xianzhou"
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A self-sustaining nanoplatform overcomes TRAIL-resistance of pancreatic cancer by a source-broadening and expenditure-reducing apoptosis strategy
Published in Materials & design (01-12-2021)“…[Display omitted] •Death receptor on TRAIL-resistant pancreatic cancer was reversely upregulated by SSN.•The upregulation enhanced tumor cumulation of SSN,…”
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Tumor Environment Regression Therapy Implemented by Switchable Prune‐to‐Essence Nanoplatform Unleashed Systemic Immune Responses
Published in Advanced science (01-12-2023)“…Coevolution of tumor cells and surrounding stroma results in protective protumoral environment, in which abundant vessel, stiff structure and immunosuppression…”
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Advances and applications of nanoparticles in cancer therapy
Published in MedComm - Oncology (01-03-2024)“…Rapid growth in nanoparticles (NPs) as delivery systems holds vast promise to promote therapeutic approaches for cancer treatment. Presently, a diverse array…”
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A tumor pH-responsive autocatalytic nanoreactor as a H 2 O 2 and O 2 self-supplying depot for enhanced ROS-based chemo/photodynamic therapy
Published in Acta biomaterialia (01-12-2022)“…Combining the internal force-driven chemodynamic therapy (CDT) and the external energy-triggered photodynamic therapy (PDT) holds great promise to achieve an…”
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Multifunctional light-activatable nanocomplex conducting temperate-heat photothermal therapy to avert excessive inflammation and trigger augmented immunotherapy
Published in Biomaterials (01-11-2022)“…Photothermal therapy (PTT) has been known as an effective weapon against cancer. However, the necrosis induced by hyperthermia post PTT can trigger excessive…”
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A tumor pH-responsive autocatalytic nanoreactor as a H2O2 and O2 self-supplying depot for enhanced ROS-based chemo/photodynamic therapy
Published in Acta biomaterialia (01-12-2022)“…Combining the internal force-driven chemodynamic therapy (CDT) and the external energy-triggered photodynamic therapy (PDT) holds great promise to achieve an…”
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A self-sustained nanoplatform reverses TRAIL-resistance of pancreatic cancer through coactivating of exogenous and endogenous apoptotic pathway
Published in Biomaterials (01-05-2021)“…Since the 5-year survival rate of pancreatic cancer is only 10.0%, new therapies are urgently needed. Tumor necrosis factor-related apoptosis-inducing ligand…”
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A Quad-Functional On-demand released nanomissile achieves cascade amplification therapy of Triple-Negative breast cancer through reversing multiple resistance
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (01-04-2023)“…[Display omitted] •A quad-functional on-demand released Nanomissile (IGN Lipo) is reported.•The Nanomissile reverses multiple resistance by inhibiting…”
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Utilizing glutathione-triggered nanoparticles to enhance chemotherapy of lung cancer by reprograming the tumor microenvironment
Published in International journal of pharmaceutics (01-12-2018)“…[Display omitted] In the present study, we have developed the robust nanoparticles (MGC-GNP/PTX), which are TAMs and tumor cells-dual recognizable, for…”
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10
Programmable double-unlock nanocomplex self-supplies phenylalanine ammonia-lyase for precise phenylalanine deprivation of tumors
Published in Chinese chemical letters (01-08-2024)“…Essential amino acids (EAAs) deprivation is a potential antitumor approach because EAAs are critical for tumor growth. To efficiently inhibit tumor growth,…”
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Effects of nutritional level of concentrate‐based diets on meat quality and expression levels of genes related to meat quality in Hainan black goats
Published in Animal science journal (01-02-2015)“…The present study investigated the effects of the nutritional levels of diets on meat quality and related gene expression in Hainan black goat. Twenty‐four…”
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TRAIL mutant membrane penetrating peptide alike (TMPPA) TRAIL-Mu3 enhances the antitumor effects of TRAIL in vitro and in vivo
Published in Molecular medicine reports (01-12-2017)“…The aim of the present study was to prepare a tumor necrosis factor ligand superfamily member 10 (TRAIL) mutant membrane penetrating peptide alike (TMPPA),…”
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Effects of nutrition level of concentrate-based diets on growth performance and carcass characteristics of Hainan black goats
Published in Tropical animal health and production (01-06-2014)“…This study assessed the effects of different nutrition levels of diets on growth performance and carcass characteristics of Hainan black goat. Twenty-four…”
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Generation of a novel TRAIL mutant by proline to arginine substitution based on codon bias and its antitumor effects
Published in Molecular medicine reports (01-10-2017)“…TNF ligand superfamily member 10 (TRAIL) is a member of the tumor necrosis factor superfamily. The present study was performed in an effort to increase the…”
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Effects of nutritional level of concentrate‐based diets on meat quality and expression levels of genes related to meat quality in H ainan black goats
Published in Animal science journal (01-02-2015)“…Abstract The present study investigated the effects of the nutritional levels of diets on meat quality and related gene expression in H ainan black goat…”
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Associated analysis of single nucleotide polymorphisms of IGF2 gene’s exon 8 with growth traits in Wuzhishan pig
Published in Molecular biology reports (2010)“…A new SNP located in IGF-2 gene of Wuzhishan pig was detected while a C → T silent mutation at position 17 of exon 8 was detected by Single-Strand…”
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An optimized control method of multifactor for greenhouse microclimate based on crop photosynthesis rate
Published in 2014 15th International Conference on Sciences and Techniques of Automatic Control and Computer Engineering (STA) (01-12-2014)“…According to the recent situation that there is less feasible greenhouse controlling strategy been presented, an optimized energy-saving control method of…”
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