Search Results - "Huang, Wendong"

A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD) by Peng, Jiangling, Fan, Mingjie, An, Chelsea, Ni, Feng, Huang, Wendong, Luo, Jiankang

“…Cannabidiol (CBD) is an abundant non‐psychoactive phytocannabinoid in cannabis extracts which has high affinity on a series of receptors, including Type 1…”
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Bile acid nuclear receptor FXR and digestive system diseases by Ding, Lili, Yang, Li, Wang, Zhengtao, Huang, Wendong

“…Bile acids(BAs) are not only digestive surfactants but also important cell signaling molecules,which stimulate several signaling pathways to regulate some…”
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H19 potentiates let-7 family expression through reducing PTBP1 binding to their precursors in cholestasis by Zhang, Li, Yang, Zhihong, Huang, Wendong, Wu, Jianguo

“…Cholestasis induces the hepatic long non-coding RNA H19, which promotes the progression of cholestatic liver fibrosis. However, microRNAs that are dysregulated…”
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Alternative approaches to target Myc for cancer treatment by Wang, Chen, Zhang, Jiawei, Yin, Jie, Gan, Yichao, Xu, Senlin, Gu, Ying, Huang, Wendong

“…The Myc proto-oncogene family consists of three members, C-MYC , MYCN , and MYCL , which encodes the transcription factor c-Myc (hereafter Myc), N-Myc, and…”
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A gut feeling for drugs that have metabolic benefits by Zhang, Eryun, Agua, Alon, Huang, Wendong

“…Resveratrol (REV) is a natural polyphenol with anti-obesity effects. However, the mechanisms remain unclear due to its low bioavailability and the lack of…”
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METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis by Su, Rui, Dong, Lei, Li, Yangchan, Gao, Min, He, P. Cody, Liu, Wei, Wei, Jiangbo, Zhao, Zhicong, Gao, Lei, Han, Li, Deng, Xiaolan, Li, Chenying, Prince, Emily, Tan, Brandon, Qing, Ying, Qin, Xi, Shen, Chao, Xue, Meilin, Zhou, Keren, Chen, Zhenhua, Xue, Jianhuang, Li, Wei, Qin, Hanjun, Wu, Xiwei, Sun, Miao, Nam, Yunsun, Chen, Chun-Wei, Huang, Wendong, Horne, David, Rosen, Steven T., He, Chuan, Chen, Jianjun

“…METTL16 has recently been identified as an RNA methyltransferase responsible for the deposition of N 6 -methyladenosine (m 6 A) in a few transcripts. Whether…”
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Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells by Zhang, Jiawei, Gan, Yichao, Li, Hongzhi, Yin, Jie, He, Xin, Lin, Liming, Xu, Senlin, Fang, Zhipeng, Kim, Byung-wook, Gao, Lina, Ding, Lili, Zhang, Eryun, Ma, Xiaoxiao, Li, Junfeng, Li, Ling, Xu, Yang, Horne, David, Xu, Rongzhen, Yu, Hua, Gu, Ying, Huang, Wendong

“…Cyclin-dependent kinase 2 (CDK2) complex is significantly over-activated in many cancers. While it makes CDK2 an attractive target for cancer therapy, most…”
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Pancreatic β cell microRNA-26a alleviates type 2 diabetes by improving peripheral insulin sensitivity and preserving β cell function by Xu, Haixia, Du, Xiao, Xu, Jia, Zhang, Yu, Tian, Yan, Liu, Geng, Wang, Xiuxuan, Ma, Meilin, Du, Wenya, Liu, Yu, Dai, Lunzhi, Huang, Wendong, Tong, Nanwei, Wei, Yuquan, Fu, Xianghui

“…Type 2 diabetes (T2D) is characterized by insulin resistance along with pancreatic β cell failure. β cell factors are traditionally thought to control glucose…”
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Intestinal AMPK modulation of microbiota mediates crosstalk with brown fat to control thermogenesis by Zhang, Eryun, Jin, Lihua, Wang, Yangmeng, Tu, Jui, Zheng, Ruirong, Ding, Lili, Fang, Zhipeng, Fan, Mingjie, Al-Abdullah, Ismail, Natarajan, Rama, Ma, Ke, Wang, Zhengtao, Riggs, Arthur D., Shuck, Sarah C., Yang, Li, Huang, Wendong

“…The energy-dissipating capacity of brown adipose tissue through thermogenesis can be targeted to improve energy balance. Mammalian 5′-AMP-activated protein…”
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Bile acids, gut microbiota and metabolic surgery by Tu, Jui, Wang, Yangmeng, Jin, Lihua, Huang, Wendong

“…Metabolic surgery, or bariatric surgery, is currently the most effective approach for treating obesity and its complications. Vertical sleeve gastrectomy (VSG)…”
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Efficacy of antidepressant drugs in the treatment of depression in Alzheimer disease patients: A systematic review and network meta-analysis by He, Yanhong, Li, Hao, Huang, Jinbo, Huang, Sumei, Bai, Yunpeng, Li, Yingbang, Huang, Wendong

“…Background: Depression is considered as one of the most common neuropsychiatric symptoms (NPS) in Alzheimer’s disease (AD) patients. Prescription of…”
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Curcumin rescues high fat diet-induced obesity and insulin sensitivity in mice through regulating SREBP pathway by Ding, Lili, Li, Jinmei, Song, Baoliang, Xiao, Xu, Zhang, Binfeng, Qi, Meng, Huang, Wendong, Yang, Li, Wang, Zhengtao

“…Obesity and its major co-morbidity, type 2 diabetes, have reached an alarming epidemic prevalence without an effective treatment available. It has been…”
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TAE-Net: Task-Adaptive Embedding Network for Few-Shot Remote Sensing Scene Classification by Huang, Wendong, Yuan, Zhengwu, Yang, Aixia, Tang, Chan, Luo, Xiaobo

“…Recently, approaches based on deep learning are quite prevalent in the area of remote sensing scene classification. Though significant success has been…”
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Bile Acids, Intestinal Barrier Dysfunction, and Related Diseases by Shi, Linsen, Jin, Lihua, Huang, Wendong

“…The intestinal barrier is a precisely regulated semi-permeable physiological structure that absorbs nutrients and protects the internal environment from…”
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Graph-Based Embedding Smoothing Network for Few-Shot Scene Classification of Remote Sensing Images by Yuan, Zhengwu, Huang, Wendong, Tang, Chan, Yang, Aixia, Luo, Xiaobo

“…As a fundamental task in the field of remote sensing, scene classification is increasingly attracting attention. The most popular way to solve scene…”
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Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response by Wang, Yan‐Dong, Chen, Wei‐Dong, Wang, Meihua, Yu, Donna, Forman, Barry M., Huang, Wendong

“…The farnesoid X receptor (FXR) is a nuclear receptor that plays key roles in hepatoprotection by maintaining the homeostasis of liver metabolism. FXR null mice…”
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Vertical sleeve gastrectomy activates GPBAR‐1/TGR5 to sustain weight loss, improve fatty liver, and remit insulin resistance in mice by Ding, Lili, Sousa, Kyle M., Jin, Lihua, Dong, Bingning, Kim, Byung‐Wook, Ramirez, Ricardo, Xiao, Zhenzhou, Gu, Ying, Yang, Qiaoling, Wang, Jie, Yu, Donna, Pigazzi, Alessio, Schones, Dustin, Yang, Li, Moore, David, Wang, Zhengtao, Huang, Wendong

“…Vertical sleeve gastrectomy (VSG) is one of the most commonly performed clinical bariatric surgeries used for the remission of obesity and diabetes. However,…”
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The G‐Protein‐coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light‐chain enhancer of activated B cells (NF‐κB) in mice by Wang, Yan‐Dong, Chen, Wei‐Dong, Yu, Donna, Forman, Barry M., Huang, Wendong

“…Gpbar1 (TGR5), a membrane‐bound bile acid receptor, is well known for its roles in regulation of energy homeostasis and glucose metabolism. TGR5 also displays…”
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Acetylshikonin from Zicao Prevents Obesity in Rats on a High-Fat Diet by Inhibiting Lipid Accumulation and Inducing Lipolysis by Su, Meiling, Huang, Wendong, Zhu, Banghao

“…Various drugs have been developed to treat obesity, but these have undesirable secondary effects, and an efficient but non-toxic anti-obesity drug from natural…”
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Few-Shot Remote Sensing Image Scene Classification Based on Metric Learning and Local Descriptors by Yuan, Zhengwu, Tang, Chan, Yang, Aixia, Huang, Wendong, Chen, Wang

“…Scene classification is a critical technology to solve the challenges of image search and image recognition. It has become an indispensable and challenging…”
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