Search Results - "Huang, Weishan"
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1
Secularity and Urban Gentrification: An Spatial Analysis of Downtown Buddhist Temples in Shanghai
Published in Space and culture (01-05-2023)“…This essay examines the relationship between the processes of urban change and the politically and commercially constructed nature of Buddhism since 1978 in…”
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2
HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2
Published in Proceedings of the National Academy of Sciences - PNAS (19-03-2019)“…The smallest histone deacetylase (HDAC) and the only class IV HDAC member, HDAC11, is reported to regulate immune activation and tumorigenesis, yet its…”
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3
Mutations and Evolution of the SARS-CoV-2 Spike Protein
Published in Viruses (01-03-2022)“…The SARS-CoV-2 spike protein mediates target recognition, cellular entry, and ultimately the viral infection that leads to various levels of COVID-19…”
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4
ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells
Published in Nature communications (21-06-2017)“…Type 1 regulatory T (Tr1) cells differentiate in response to signals engaging the T cell receptor (TCR), express high levels of the immunosuppressive cytokine…”
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5
Adeno-associated viral vector-mediated immune responses: Understanding barriers to gene delivery
Published in Pharmacology & therapeutics (Oxford) (01-03-2020)“…Adeno-associated viral (AAV) vectors have emerged as the leading gene delivery platform for gene therapy and vaccination. Three AAV-based gene therapy drugs,…”
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6
Altered Blood Cell Traits Underlie a Major Genetic Locus of Severe COVID-19
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-08-2021)“…Abstract Background The genetic locus 3p21.31 has been associated with severe coronavirus disease 2019 (COVID-19), but the underlying pathophysiological…”
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7
Thymic regulatory T cells arise via two distinct developmental programs
Published in Nature immunology (01-02-2019)“…The developmental programs that generate a broad repertoire of regulatory T cells (T reg cells) able to respond to both self antigens and non-self antigens…”
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Author Correction: ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells
Published in Nature communications (19-05-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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9
Beyond Type 1 Regulatory T Cells: Co-expression of LAG3 and CD49b in IL-10-Producing T Cell Lineages
Published in Frontiers in immunology (19-11-2018)“…Type 1 regulatory CD4 T (Tr1) cells express high levels of the immunosuppressive cytokine IL-10 but not the master transcription factor Foxp3, and can suppress…”
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10
PD-1 and ICOS counter-regulate tissue resident regulatory T cell development and IL-10 production during flu
Published in Frontiers in immunology (08-09-2022)“…Regulatory T cells that express the transcription factor Foxp3 (Treg cells) are a highly heterogenous population of immunoregulatory cells critical for…”
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11
Farnesyl pyrophosphate is a new danger signal inducing acute cell death
Published in PLoS biology (26-04-2021)“…Cell death is a vital event in life. Infections and injuries cause lytic cell death, which gives rise to danger signals that can further induce cell death,…”
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12
Amino acid starvation sensing dampens IL-1β production by activating riboclustering and autophagy
Published in PLoS biology (05-04-2018)“…Activation of the amino acid starvation response (AAR) increases lifespan and acute stress resistance as well as regulates inflammation. However, the…”
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13
Targeting kinase ITK treats autoimmune arthritis via orchestrating T cell differentiation and function
Published in Biomedicine & pharmacotherapy (31-12-2023)“…IL-2 inducible T cell kinase (ITK) is critical in T helper subset differentiation and its inhibition has been suggested for the treatment of T cell-mediated…”
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14
Correction: Magazine et al. Mutations and Evolution of the SARS-CoV-2 Spike Protein. Viruses 2022, 14, 640
Published in Viruses (23-08-2023)“…In the original publication [...]…”
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15
Neuropilin-1 Identifies a New Subpopulation of TGF-β-Induced Foxp3 + Regulatory T Cells With Potent Suppressive Function and Enhanced Stability During Inflammation
Published in Frontiers in immunology (04-05-2022)“…CD4 Foxp3 regulatory T cells (Tregs) play a crucial role in preventing autoimmunity and inflammation. There are naturally-derived in the thymus (tTreg),…”
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16
Research on power management and allowed propulsion control in pure electric vehicle
Published in Energy reports (01-04-2022)“…For the optimization of vehicle mode management, the vehicle safety and the system efficiency, seven states which include initialization, the CPSR off, the…”
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17
Targeting Interleukin-2-Inducible T-Cell Kinase (ITK) Differentiates GVL and GVHD in Allo-HSCT
Published in Frontiers in immunology (26-11-2020)“…Allogeneic hematopoietic stem cell transplantation is a potentially curative procedure for many malignant diseases. Donor T cells prevent disease recurrence…”
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18
Nonreceptor tyrosine kinases ITK and BTK negatively regulate mast cell proinflammatory responses to lipopolysaccharide
Published in Journal of allergy and clinical immunology (01-04-2016)“…Background Mast cells are indispensable for LPS-induced septic hypothermia, in which TNF-α plays an essential role to initiate septic responses. ITK and BTK…”
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Effective differentiation of double negative thymocytes requires high fidelity replication of mitochondrial DNA in an age dependent manner
Published in Frontiers in immunology (20-03-2023)“…One of the most proliferative periods for T cells occurs during their development in the thymus. Increased DNA replication can result in increased DNA…”
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Neurologic manifestations of nonhospitalized patients with COVID‐19 in Wuhan, China
Published in MedComm (2020) (01-09-2020)“…Notably, our results revealed that neurologic manifestations were common in nonhospitalized patients in Wuhan (total, 77.8%; CNS, 46.7%; PNS, 69.3%), and the…”
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