Search Results - "Huang, Weei"

IL‐17R deletion predicts high‐grade colorectal cancer and poor clinical outcomes by Yan, Chi, Huang, Weei‐Yuan, Boudreau, Jeanette, Mayavannan, Animamalar, Cheng, Zhenyu, Wang, Jun

“…The IL‐17 receptor (IL‐17R) has a perplexing role in cancer, which may be explained by its yin‐yang signaling pathways. Recently, the critical role of IL‐17R…”
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S100A10, a novel biomarker in pancreatic ductal adenocarcinoma by Bydoun, Moamen, Sterea, Andra, Liptay, Henry, Uzans, Andrea, Huang, Weei‐Yuarn, Rodrigues, Gloria J., Weaver, Ian C.G., Gu, Hong, Waisman, David M.

“…Pancreatic cancer is arguably the deadliest cancer type. The efficacy of current therapies is often hindered by the inability to predict patient outcome. As…”
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Genetic profiles of different subsets of Merkel cell carcinoma show links between combined and pure MCPyV-negative tumors by Carter, Michael D., Gaston, Dan, Huang, Weei-Yuarn, Greer, Wenda L., Pasternak, Sylvia, Ly, Thai Yen, Walsh, Noreen M.

“…Tumorigenesis in Merkel cell carcinoma (MCC) is driven by (1) clonal integration of the Merkel cell polyomavirus (MCPyV) in neoplastic cells and/or (2) genetic…”
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Strategies for Overcoming Resistance in Tumours Harboring BRAF Mutations by Obaid, Nourah Mohammad, Bedard, Karen, Huang, Weei-Yuarn

“…The development of resistance to previously effective treatments has been a challenge for health care providers and a fear for patients undergoing cancer…”
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Referred molecular testing as a barrier to optimal treatment decision making in metastatic non‐small cell lung cancer: Experience at a tertiary academic institution in Canada by Grafham, Grace K., Craddock, Kenneth J., Huang, Weei‐Yuarn, Louie, Alexander V., Zhang, Liying, Hwang, David M., Parmar, Ambica

“…Background Molecular testing is critical to guiding treatment approaches in patients with metastatic non‐small cell lung cancer (mNSCLC), with testing delays…”
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Characterization of genome-wide copy number aberrations in colonic mixed adenoneuroendocrine carcinoma and neuroendocrine carcinoma reveals recurrent amplification of PTGER4 and MYC genes by Sinha, Namita, Gaston, Daniel, Manders, Daniel, Goudie, Marissa, Matsuoka, Makoto, Xie, Tao, Huang, Weei-Yuarn

“…Colonic mixed adenoneuroendocrine carcinoma (MANEC) is an aggressive neoplasm with worse prognosis compared with adenocarcinoma. To gain a better understanding…”
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Canadian ROS proto-oncogene 1 study (CROS) for multi-institutional implementation of ROS1 testing in non-small cell lung cancer by Cheung, Carol C., Smith, Adam C., Albadine, Roula, Bigras, Gilbert, Bojarski, Anna, Couture, Christian, Cutz, Jean-Claude, Huang, Weei-Yuan, Ionescu, Diana, Itani, Doha, Izevbaye, Iyare, Karsan, Aly, Kelly, Margaret M., Knoll, Joan, Kwan, Keith, Nasr, Michel R., Qing, Gefei, Rashid-Kolvear, Fariboz, Sekhon, Harmanjatinder S., Spatz, Alan, Stockley, Tracy, Tran-Thanh, Danh, Tucker, Tracy, Waghray, Ranjit, Wang, Hangjun, Xu, Zhaolin, Yatabe, Yasushi, Torlakovic, Emina E., Tsao, Ming-Sound

“…•High quality ROS1 IHC assays have high clinical utility.•Adjusting readout can increase diagnostic accuracy in ROS1 IHC.•ROS1 IHC readout must be balanced…”
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Comparing Pathology Report Quality Indicators in 2 Distinct Whipple Resection Specimen Protocols by DeCoste, Ryan, McDonell, Laura M., Uzans, Drea, Molinari, Michele, Huang, Weei-Yuarn

“…Pancreaticoduodenectomy specimens are complex, with varying gross examination techniques. In 2012, our institution began using axial sectioning. We sought to…”
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A growing vulvar mass in a post-menopausal woman by Xie, Youheng, Mata, Danilo Giffoni M M, Huang, Weei-Yuarn, Djordjevic, Bojana, Jerzak, Katarzyna Joanna

“…Weak and patchy p16 staining was consistent with non-human papillomavirus-related gynaecological carcinoma (figure, A). Biomarker analysis showed oestrogen…”
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Evaluating Targeted Next-Generation Sequencing Assays and Reference Materials for NTRK Fusion Detection by Bormann Chung, Christina, Lee, Jeeyun, Barritault, Marc, Bringuier, Pierre-Paul, Xu, Zhaolin, Huang, Weei-Yuarn, Beharry, Andrea, Castillo, Joseph, Christiansen, Jason, Lin, Jennifer C., Sheffield, Brandon S.

“…Neurotrophic tyrosine receptor kinase (NTRK1/2/3) fusions are oncogenic drivers in approximately 0.3% of solid tumors. High-quality testing to identify…”
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Deep learning for computer-assisted diagnosis of hereditary diffuse gastric cancer by Rasmussen, Sean A, Arnason, Thomas, Huang, Weei-Yuarn

“…Patients with hereditary diffuse gastric cancer often undergo prophylactic gastrectomy to minimize cancer risk. Because intramucosal poorly cohesive carcinomas…”
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Validation of a Cytotechnologist Manual Counting Service for the Ki67 Index in Neuroendocrine Tumors of the Pancreas and Gastrointestinal Tract by Cottenden, Jennielee, Filter, Emily R, Cottreau, Jon, Moore, David, Bullock, Martin, Huang, Weei-Yuarn, Arnason, Thomas

“…- Pathologists routinely assess Ki67 immunohistochemistry to grade gastrointestinal and pancreatic neuroendocrine tumors. Unfortunately, manual counts of the…”
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The Insulin-like Growth Factor 1 Receptor Induces Physiological Heart Growth via the Phosphoinositide 3-Kinase(p110α) Pathway by McMullen, Julie R., Shioi, Tetsuo, Huang, Weei-Yuarn, Zhang, Li, Tarnavski, Oleg, Bisping, Egbert, Schinke, Martina, Kong, Sekwon, Sherwood, Megan C., Brown, Jeffrey, Riggi, Lauren, Kang, Peter M., Izumo, Seigo

“…Insulin-like growth factor 1 (IGF1) was considered a potential candidate for the treatment of heart failure. However, some animal studies and clinical trials…”
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The analysis of microsatellite instability in extracolonic gastrointestinal malignancy by Williams, Andrew S., Huang, Weei-Yuarn

“…Microsatellite instability (MSI) is a genetic feature of sporadic and familial cancers of multiple sites and is related to defective mismatch repair (MMR)…”
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Intrarenal urothelial transformation after obstruction: a novel metaplasia by Huang, Weei-Yuarn, Rosen, Seymour

“…Obstructive nephropathy is a major cause of acute renal failure and end-stage renal disease. We discuss the new findings of Girshovich et al., who show that…”
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ACTH-Secreting Neuroendocrine Carcinoma of the Cecum: Case Report and Review of the Literature by Mokhtar, Ahmed, Arnason, Thomas, Gaston, Daniel, Huang, Weei-Yuarn, MacKenzie, Heather, Al-Hazmi, Rayan, Vaninetti, Nadine, Tugwell, Barna, Rayson, Daniel

“…Adrenocorticotropic hormone-secreting neuroendocrine tumors of the colon are rare. We describe a case of BRAF V600E and TP53 mutations detected with…”
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Goblet cell carcinoid of the appendix – An interobserver variability study using two proposed classification systems by Maedler, Chelsea, Arnason, Thomas, Dorreen, Alastair, Sapp, Heidi, Castonguay, Mathieu, Murphy, Joanne, Selegean, Sorin, Huang, Weei-Yuarn

“…Goblet cell carcinoid (GCC) is an uncommon tumor of the vermiform appendix. Due to a broad spectrum of morphological differentiation, subclassification and…”
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Acute liver failure induced by green tea extracts: Case report and review of the literature by Molinari, Michele, Watt, Kymberly D.S., Kruszyna, Thomas, Nelson, Rebecca, Walsh, Mark, Huang, Weei‐Yuan, Nashan, Bjorn, Peltekian, Kevork

“…In industrialized countries, over‐the‐counter dietary supplements have become popular in preventing and treating an expanding list of medical conditions…”
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Exosomal proteomic analysis reveals changes in the urinary proteome of rats with unilateral ureteral obstruction by Orton, Dennis J, Doucette, Alan A, Huang, Weei-Yuarn, MacLellan, Dawn L

“…Congenital urinary tract obstruction (UTO) is a commonly noted disorder with the potential to cause permanent loss of renal function. Due to the possibility of…”
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Microsatellite instability status does not predict total lymph node or negative lymph node retrieval in stage III colon cancer by MacQuarrie, Erin, MD, Arnason, Thomas, MD, Gruchy, Jennette, MD, Yan, Sen, MD, FRCPC, Drucker, Arik, MD, FRCPC, Huang, Weei-Yuarn, MD, PhD, FRCPC

“…Summary The relationship between higher total lymph node resection number in colorectal cancer resection specimens and improved overall survival is well known…”
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