Search Results - "Huang, Susan M"

TRPV3 and TRPV4 Ion Channels are Not Major Contributors to Mouse Heat Sensation by Huang, Susan M, Li, Xiaoxin, Yu, YinYin, Wang, Juan, Caterina, Michael J

“…Background: The discovery of heat-sensitive Transient Receptor Potential Vanilloid (TRPV) ion channels provided a potential molecular explanation for the…”
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Overexpressed Transient Receptor Potential Vanilloid 3 Ion Channels in Skin Keratinocytes Modulate Pain Sensitivity via Prostaglandin E2 by Huang, Susan M, Lee, Hyosang, Chung, Man-Kyo, Park, Una, Yu, Yin Yin, Bradshaw, Heather B, Coulombe, Pierre A, Walker, J. Michael, Caterina, Michael J

“…The ability to sense changes in the environment is essential for survival because it permits responses such as withdrawal from noxious stimuli and regulation…”
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An Endogenous Capsaicin-like Substance with High Potency at Recombinant and Native Vanilloid VR1 Receptors by Huang, Susan M., Bisogno, Tiziana, Trevisani, Marcello, Al-Hayani, Abdulmonem, De Petrocellis, Luciano, Fezza, Filomena, Tognetto, Michele, Petros, Timothy J., Krey, Jocelyn F., Chu, Constance J., Miller, Jeffrey D., Davies, Stephen N., Geppetti, Pierangelo, Walker, J. Michael, Di Marzo, Vincenzo

“…The vanilloid receptor VR1 is a nonselective cation channel that is most abundant in peripheral sensory fibers but also is found in several brain nuclei. VR1…”
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N-Oleoyldopamine, a Novel Endogenous Capsaicin-like Lipid That Produces Hyperalgesia by Chu, Constance J., Huang, Susan M., De Petrocellis, Luciano, Bisogno, Tiziana, Ewing, Scott A., Miller, Jeffrey D., Zipkin, Robert E., Daddario, Nives, Appendino, Giovanni, Di Marzo, Vincenzo, Walker, J. Michael

“…N-Arachidonoyldopamine (NADA) was recently identified as an endogenous ligand for the vanilloid type 1 receptor (VR1). Further analysis of the bovine striatal…”
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Loss of Bardet-Biedl syndrome proteins causes defects in peripheral sensory innervation and function by Tan, Perciliz L, Barr, Travis, Inglis, Peter N, Mitsuma, Norimasa, Huang, Susan M, Garcia-Gonzalez, Miguel A, Bradley, Brian A, Coforio, Stephanie, Albrecht, Phillip J, Watnick, Terry, Germino, Gregory G, Beales, Philip L, Caterina, Michael J, Leroux, Michel R, Rice, Frank L, Katsanis, Nicholas

“…Reception and interpretation of environmental stimuli is critical for the survival of all organisms. Here, we show that the ablation of BBS1 and BBS4, two…”
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Endocannabinoids and related fatty acid derivatives in pain modulation by Walker, J.Michael, Krey, Jocelyn F., Chu, Constance J., Huang, Susan M.

“…The brain produces at least five compounds that possess sub-micromolar affinity for cannabinoid receptors: anandamide, 2-arachidonoylglycerol, noladin ether,…”
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TRP Channel Regulates EGFR Signaling in Hair Morphogenesis and Skin Barrier Formation by Cheng, Xiping, Jin, Jie, Hu, Lily, Shen, Dongbiao, Dong, Xian-ping, Samie, Mohammad A., Knoff, Jayne, Eisinger, Brian, Liu, Mei-ling, Huang, Susan M., Caterina, Michael J., Dempsey, Peter, Michael, Lowell Evan, Dlugosz, Andrzej A., Andrews, Nancy C., Clapham, David E., Xu, Haoxing

“…A plethora of growth factors regulate keratinocyte proliferation and differentiation that control hair morphogenesis and skin barrier formation. Wavy hair…”
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Persistence of Inflammatory Phenotype in Residual Psoriatic Plaques in Patients on Effective Biologic Therapy by Mashiko, Shunya, Edelmayer, Rebecca M., Bi, Yingtao, Olson, Lauren M., Wetter, Joseph B., Wang, Jing, Maari, Catherine, Saint-Cyr Proulx, Etienne, Kaimal, Vivek, Li, Xuan, Salte, Katherine, Garcet, Sandra, Kannan, Arun K., Huang, Susan M., Cao, Xiaohong, Liu, Zheng, Krueger, James G., Sarfati, Marika, Bissonnette, Robert, Smith, Kathleen M.

“…Many psoriasis patients treated with biologics do not achieve total skin clearance. These patients possess residual plaques despite ongoing biologic treatment…”
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Cannabinoid signaling in rat cerebellar granule cells: G-protein activation, inhibition of glutamate release and endogenous cannabinoids by Breivogel, Christopher S., Walker, J.Michael, Huang, Susan M., Roy, Mary Beth, Childers, Steven R.

“…Previous studies have indicated that cannabinoids inhibit presynaptic neurotransmitter release in brain through CB 1 receptors. To examine this issue in a…”
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Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain by Moussaieff, Arieh, Rimmerman, Neta, Bregman, Tatiana, Straiker, Alex, Felder, Christian C, Shoham, Shai, Kashman, Yoel, Huang, Susan M, Lee, Hyosang, Shohami, Esther, Mackie, Ken, Caterina, Michael J, Walker, J. Michael, Fride, Ester, Mechoulam, Raphael

“…Burning of Boswellia resin as incense has been part of religious and cultural ceremonies for millennia and is believed to contribute to the spiritual…”
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Interactive Mobile Doctor (iMD) to Promote Patient-Provider Discussion on Tobacco Use among Asian American Patients in Primary Care: A Pilot Study by Tsoh, Janice Y, Quach, Thu, Duong, Thomas B, Sa Nan Park, Emily, Wong, Ching, Huang, Susan M, Nguyen, Tung T

“…This study examined the feasibility, acceptability, and efficacy of an interactive "Mobile Doctor" intervention (iMD) for Korean and Vietnamese American men,…”
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Cannabinoid analgesia by Walker, J.Michael, Huang, Susan M

“…During the last decade, rigorous scientific methods have been applied to determine the effects of cannabinoids on nociceptive neurotransmission. Cannabinoids…”
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The biosynthesis of N -arachidonoyl dopamine (NADA), a putative endocannabinoid and endovanilloid, via conjugation of arachidonic acid with dopamine by Hu, Sherry Shu-Jung, Bradshaw, Heather B, Benton, Valery M, Chen, Jay Shih-Chieh, Huang, Susan M, Minassi, Alberto, Bisogno, Tiziana, Masuda, Kim, Tan, Bo, Roskoski, Robert, Cravatt, Benjamin F, Di Marzo, Vincenzo, Walker, J. Michael

“…Abstract N -arachidonoyl dopamine (NADA) is an endogenous ligand that activates the cannabinoid type 1 receptor and the transient receptor potential vanilloid…”
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Pain Modulation by Release of the Endogenous Cannabinoid Anandamide by Walker, J. Michael, Huang, Susan M., Strangman, Nicole M., Tsou, Kang, Sanudo-Pena, M. Clara

“…Synthetic cannabinoids produce behavioral analgesia and suppress pain neurotransmission, raising the possibility that endogenous cannabinoids serve naturally…”
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Identification of a New Class of Molecules, the Arachidonyl Amino Acids, and Characterization of One Member That Inhibits Pain by Huang, S M, Bisogno, T, Petros, T J, Chang, S Y, Zavitsanos, P A, Zipkin, R E, Sivakumar, R, Coop, A, Maeda, D Y, De Petrocellis, L, Burstein, S, Di Marzo, V, Walker, J M

“…In mammals, specific lipids and amino acids serve as crucial signaling molecules. In bacteria, conjugates of lipids and amino acids (referred to as lipoamino…”
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Targeting TRPV3 for the Development of Novel Analgesics by Huang, Susan M, Chung, Man-Kyo

“…Decades of characterization of the transient receptor potential vanilloid subtype 1 (TRPV1) has led to the realization of its central role in thermosensation…”
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Enhancement of Spontaneous and Heat-Evoked Activity in Spinal Nociceptive Neurons by the Endovanilloid/Endocannabinoid N-Arachidonoyldopamine (NADA) by Huang, Susan M, Walker, J. Michael

“…1 Departments of Neuroscience and Psychology, Brown University, Providence, Rhode Island; and 2 Department of Psychological and Brain Sciences, Indiana…”
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Regulation of anandamide tissue levels by N-arachidonylglycine by Burstein, Sumner H., Huang, Susan M., Petros, Timothy J., Rossetti, Ronald G., Walker, J Michael, Zurier, Robert B.

“…N-Arachidonylglycine (NAGly), the carboxylic analog of the endocannabinoid anandamide, occurs in rat and bovine brain as well as in peripheral sites and shows…”
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Targeted lipidomics: fatty acid amides and pain modulation by Walker, J. Michael, Krey, Jocelyn F., Chen, Jay S., Vefring, Eivind, Jahnsen, Jan A., Bradshaw, Heather, Huang, Susan M.

“…Mass spectrometric approaches to the identification and quantification of lipid signalling molecules are reviewed. Fatty acid amides are an important new class…”
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Cannabinoids and pain by Walker, J M, Strangman, N M, Huang, S M

“…Cannabinoids have been used to treat pain for many centuries. However, only during the past several decades have rigorous scientific methods been applied to…”
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