Search Results - "Huang, Sunny C."
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High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9
Published in Genome research (01-07-2015)“…The use of CRISPR/Cas9 as a genome-editing tool in various model organisms has radically changed targeted mutagenesis. Here, we present a high-throughput…”
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Dose–response relationship of cardiorespiratory fitness adaptation to controlled endurance training in sedentary older adults
Published in European journal of preventive cardiology (01-03-2016)“…Background The purpose of this investigation was to identify a quantitative dose–response relationship for enhancing maximal oxygen consumption (VO2max) in…”
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A large-scale zebrafish gene knockout resource for the genome-wide study of gene function
Published in Genome research (01-04-2013)“…With the completion of the zebrafish genome sequencing project, it becomes possible to analyze the function of zebrafish genes in a systematic way. The first…”
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A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment
Published in PLoS genetics (22-04-2021)“…Primary cilia are microtubule-based organelles present on most cells that regulate many physiological processes, ranging from maintaining energy homeostasis to…”
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An open source and convenient method for the wide-spread testing of COVID-19 using deep throat sputum samples
Published in PeerJ (San Francisco, CA) (10-05-2022)“…The rise of novel, more infectious SARS-CoV-2 variants has made clear the need to rapidly deploy large-scale testing for COVID-19 to protect public health…”
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Controlled aerobic exercise training reduces resting blood pressure in sedentary older adults
Published in Blood pressure (01-12-2013)“…The results of existing controlled clinical trials were synthesized to determine effects of aerobic exercise training on resting systolic (SBP) and diastolic…”
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Loss of Mgat5a-mediated N-glycosylation stimulates regeneration in zebrafish
Published in Cell regeneration (20-10-2016)“…Background We are using genetics to identify genes specifically involved in hearing regeneration. In a large-scale genetic screening, we identified mgat5a , a…”
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The art of virtual mentoring in the twenty-first century for STEM majors and beyond
Published in Nature biotechnology (01-12-2020)“…Social quarantine has severely impacted the training of new scientists, but the use of virtual platforms can supplement mentorship, making career development…”
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Mentoring during Uncertain Times
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01-05-2021)“…Scientific success is mainly supported by mentoring, which often occurs through face-to-face interactions. Changes to the research environment incurred by the…”
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Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes
Published in Cell metabolism (06-10-2020)“…Aberrant redox signaling underlies the pathophysiology of many chronic metabolic diseases, including type 2 diabetes (T2D). Methodologies aimed at rebalancing…”
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Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes
Published in Cell metabolism (01-12-2020)Get full text
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Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes
Published in Cell metabolism (01-11-2022)Get full text
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Additive reductions in zebrafish PRPS1 activity result in a spectrum of deficiencies modeling several human PRPS1-associated diseases
Published in Scientific reports (18-07-2016)“…Phosphoribosyl pyrophosphate synthetase-1 ( PRPS1 ) is a key enzyme in nucleotide biosynthesis and mutations in PRPS1 are found in several human diseases…”
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Extracellular HSP60 triggers tissue regeneration and wound healing by regulating inflammation and cell proliferation
Published in npj Regenerative medicine (27-10-2016)“…After injury, zebrafish can restore many tissues that do not regenerate well in mammals, making it a useful vertebrate model for studying regenerative biology…”
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Guided genetic screen to identify genes essential in the regeneration of hair cells and other tissues
Published in npj Regenerative medicine (04-06-2018)“…Regenerative medicine holds great promise for both degenerative diseases and traumatic tissue injury which represent significant challenges to the health care…”
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The Art of Virtual Mentoring in the 21st Century for STEM Majors and Beyond
Published in Nature biotechnology (01-12-2020)Get full text
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