Search Results - "Huang, Shenlin"

BioAIEgens derived from rosin: how does molecular motion affect their photophysical processes in solid state? by Cai, Xu-Min, Lin, Yuting, Li, Ying, Chen, Xinfei, Wang, Zaiyu, Zhao, Xueqian, Huang, Shenlin, Zhao, Zheng, Tang, Ben Zhong

“…The exploration of artificial luminogens with bright emission has been fully developed with the advancement of synthetic chemistry. However, many of them face…”
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LncRNA—UCA1 enhances cell proliferation and 5-fluorouracil resistance in colorectal cancer by inhibiting miR-204-5p by Bian, Zehua, Jin, Liugen, Zhang, Jiwei, Yin, Yuan, Quan, Chao, Hu, Yaling, Feng, Yuyang, Liu, Heyong, Fei, Bojian, Mao, Yong, Zhou, Leyuan, Qi, Xiaowei, Huang, Shenlin, Hua, Dong, Xing, Chungen, Huang, Zhaohui

“…Recent preliminary studies reported the in vitro tumor-promoting effects of long non-coding RNA urothelial carcinoma associated 1 (UCA1) in colorectal cancer…”
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Electroreductive hydroxy fluorosulfonylation of alkenes by Feng, Qingyuan, He, Tianyu, Qian, Shencheng, Xu, Peng, Liao, Saihu, Huang, Shenlin

“…An electroreductive strategy for radical hydroxyl fluorosulfonylation of alkenes with sulfuryl chlorofluoride and molecular oxygen from air is described. This…”
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Cationic Palladium(II) Catalysis: C−H Activation/Suzuki−Miyaura Couplings at Room Temperature by Nishikata, Takashi, Abela, Alexander R, Huang, Shenlin, Lipshutz, Bruce H

“…Cationic palladium(II) catalyst realized facile C−H activation of aryl urea with arylboronic acids at room temperature. This reaction is extremely mild to…”
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Organoelectrocatalytic cyclopropanation of alkenyl trifluoroborates with methylene compounds by Yi, Wei, Xu, Peng-Cheng, He, Tianyu, Shi, Shuai, Huang, Shenlin

“…Cyclopropanes are not only privileged motifs in many natural products, agrochemicals, and pharmaceuticals, but also highly versatile intermediates in synthetic…”
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Metal-free O-H/C-H difunctionalization of phenols by o -hydroxyarylsulfonium salts in water by Chen, Dengfeng, Feng, Qingyuan, Yang, Yunqin, Cai, Xu-Min, Wang, Fei, Huang, Shenlin

“…An environmentally benign method for C-H/O-H difunctionalization of phenols with sulfoxides under mild conditions has been developed. The reaction process is…”
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Cationic Pd(II)-catalyzed C-H activation/cross-coupling reactions at room temperature: synthetic and mechanistic studies by Nishikata, Takashi, Abela, Alexander R, Huang, Shenlin, Lipshutz, Bruce H

“…Cationic palladium(II) complexes have been found to be highly reactive towards aromatic C-H activation of arylureas at room temperature. A commercially…”
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Analytical Profiling of Proanthocyanidins from Acacia mearnsii Bark and In Vitro Assessment of Antioxidant and Antidiabetic Potential by Chen, Xiao, Xiong, Jia, Huang, Shenlin, Li, Xun, Zhang, Yu, Zhang, Liping, Wang, Fei

“…The proanthocyanidins from ethanol extracts (80%, / ) of ( ) bark on chemical-based and cellular antioxidant activity assays as well as carbolytic enzyme…”
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Evaluation of the Antifungal Activity of Polysubstituted Cyclic 1,2-Diketones against Colletotrichum gloeosporioides by Qiuyue Wang, Xiangtai Meng, Meiling Sun, Zhi Wang, Jiao He, Shenlin Huang, Lin Huang

“…(1) Anthracnose caused by Colletotrichum damages crops, ornamentals, and forest trees severely, resulting in enormous economic losses to agricultural and…”
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C–C Bond Formation via Copper-Catalyzed Conjugate Addition Reactions to Enones in Water at Room Temperature by Lipshutz, Bruce H, Huang, Shenlin, Leong, Wendy Wen Yi, Isley, Nicholas A

“…Conjugate addition reactions to enones can now be done in water at room temperature with in situ generated organocopper reagents. Mixing an enone, zinc powder,…”
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Linker Regulation: Synthesis and Electrochemical Properties of Ferrocene-Decorated Cellulose by Cai, Xu-Min, Lin, Yuting, Chen, Xinfei, Chen, Xiao, Mu, Tianqi, Huang, Shenlin, Wang, Fei

“…Ferrocene-decorated cellulosic materials are usually obtained via a couple of synthetic procedures, which might possibly affect their degree of substitution…”
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Design and Discovery of N‑(2-Methyl-5′-morpholino-6′-((tetrahydro‑2H‑pyran-4-yl)oxy)-[3,3′-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers by Nishiguchi, Gisele A, Rico, Alice, Tanner, Huw, Aversa, Robert J, Taft, Benjamin R, Subramanian, Sharadha, Setti, Lina, Burger, Matthew T, Wan, Lifeng, Tamez, Victoriano, Smith, Aaron, Lou, Yan, Barsanti, Paul A, Appleton, Brent A, Mamo, Mulugeta, Tandeske, Laura, Dix, Ina, Tellew, John E, Huang, Shenlin, Mathews Griner, Lesley A, Cooke, Vesselina G, Van Abbema, Anne, Merritt, Hanne, Ma, Sylvia, Gampa, Kalyani, Feng, Fei, Yuan, Jing, Wang, Yingyun, Haling, Jacob R, Vaziri, Sepideh, Hekmat-Nejad, Mohammad, Jansen, Johanna M, Polyakov, Valery, Zang, Richard, Sethuraman, Vijay, Amiri, Payman, Singh, Mallika, Lees, Emma, Shao, Wenlin, Stuart, Darrin D, Dillon, Michael P, Ramurthy, Savithri

“…RAS oncogenes have been implicated in >30% of human cancers, all representing high unmet medical need. The exquisite dependency on CRAF kinase in KRAS mutant…”
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Copper-in-Charcoal-Catalyzed, Tandem One-Pot Diazo Transfer-Click Reactions by Lee, Ching-Tien, Huang, Shenlin, Lipshutz, Bruce H.

“…Copper‐in‐charcoal (Cu/C) is an effective heterogeneous catalyst for tandem diazo transfer/click reactions. In the presence of Cu/C, various azides can be…”
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Enantioselective Total Synthesis of All of the Known Chiral Cleroindicins (C−F): Clarification Among Optical Rotations and Assignments by Wenderski, Todd A, Huang, Shenlin, Pettus, Thomas R. R

“…Enantioselective syntheses of all of the named chiral members of the cleroindicin family (C−F) are reported. This effort demonstrates the synthetic utility of…”
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Synthesis of 3-(1 H-benzimidazol-2-yl)-5-isoquinolin-4-ylpyrazolo[1,2- b]pyridine, a potent cyclin dependent kinase 1 (CDK1) inhibitor by Huang, Shenlin, Lin, Ronghui, Yu, Yang, Lu, Yanhua, Connolly, Peter J., Chiu, George, Li, Shengjian, Emanuel, Stuart L., Middleton, Steven A.

“…A novel compound 3-(1 H-benzimidazol-2-yl)-5-isoquinolin-4-ylpyrazolo[1,2- b]pyridine was discovered to be a potent CDK1 inhibitor. An efficient chemistry was…”
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Synthesis and evaluation of pyrazolo[3,4- b]pyridine CDK1 inhibitors as anti-tumor agents by Lin, Ronghui, Connolly, Peter J., Lu, Yanhua, Chiu, George, Li, Shengjian, Yu, Yang, Huang, Shenlin, Li, Xun, Emanuel, Stuart L., Middleton, Steven A., Gruninger, Robert H., Adams, Mary, Fuentes-Pesquera, Angel R., Greenberger, Lee M.

“…A series of 3,5-disubstituted pyrazolo[3,4- b]pyridine cyclin-dependent kinase (CDK) inhibitors was synthesized. These compounds showed potent and selective…”
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4-Aminopyrimidine-5-carbaldehyde oximes as potent VEGFR-2 inhibitors. Part II by Huang, Shenlin, Li, Ronghua, LaMontagne, Kenneth R., Greenberger, Lee M., Connolly, Peter J.

“…A series of 4-aminopyrimidine-5-carbaldehyde oximes was discovered to have potent VEGFR-2 inhibitory activities. Described here are the chemistry for analogue…”
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A Novel Three-Component One-Pot Reaction Involving Alkynes, Urea or Thiourea, and Aldehydes by Huang, Shenlin, Pan, Yuanjiang, Zhu, Yulin, Wu, Anxin

“…A novel three-component, one-pot condensation yielding 2-amino-4H-1,3-oxazines or 2-amino-4H-1,3-thiazines from alkynes, urea or thiourea, and aldehydes is…”
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Improving enzymatic hydrolysis of acid-pretreated bamboo residues using amphiphilic surfactant derived from dehydroabietic acid by Lin, Wenqian, Chen, Dengfeng, Yong, Qiang, Huang, Caoxing, Huang, Shenlin

“…[Display omitted] •The hydrophobicity of lignin was reduced by pre-adsorbing surfactants.•Amphiphilic surfactant weaken adsorption between lignin and…”
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Synthesis and evaluation of N-acyl sulfonamides as potential prodrugs of cyclin-dependent kinase inhibitor JNJ-7706621 by Huang, Shenlin, Connolly, Peter J., Lin, Ronghui, Emanuel, Stuart, Middleton, Steve A.

“…A novel prodrug strategy for cyclin-dependent kinase inhibitor JNJ-7706621 has been explored. Through N-acylation of a sulfonamide substituent, tails…”
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