Search Results - "Huang, Ruixue"
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DNA damage repair: historical perspectives, mechanistic pathways and clinical translation for targeted cancer therapy
Published in Signal transduction and targeted therapy (09-07-2021)“…Genomic instability is the hallmark of various cancers with the increasing accumulation of DNA damage. The application of radiotherapy and chemotherapy in…”
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Gut Microbiota: A Key Regulator in the Effects of Environmental Hazards on Modulates Insulin Resistance
Published in Frontiers in cellular and infection microbiology (17-01-2022)“…Insulin resistance is a hallmark of Alzheimer's disease (AD), type II diabetes (T2D), and Parkinson's disease (PD). Emerging evidence indicates that these…”
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Effect of Probiotics on Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Published in Nutrients (06-08-2016)“…It has been reported that gut probiotics play a major role in the bidirectional communication between the gut and the brain. Probiotics may be essential to…”
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Associations of Serum Total 25OHD, 25OHD3, and epi-25OHD3 with Insulin Resistance: Cross-Sectional Analysis of the National Health and Nutrition Examination Survey, 2011–2016
Published in Nutrients (26-08-2022)“…Background: Vitamin D may have a role in insulin sensitivity. However, the data on the association between various metabolites of Vitamin D and insulin-related…”
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Linking the Low-Density Lipoprotein-Cholesterol (LDL) Level to Arsenic Acid, Dimethylarsinic, and Monomethylarsonic: Results from a National Population-Based Study from the NHANES, 2003–2020
Published in Nutrients (26-09-2022)“…Arsenic (As) contamination is a global public health problem. Elevated total cholesterol (TC) and low-density lipoprotein-cholesterol (LDL-C) are risk factors…”
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Heavy Metal Contamination in Rice-Producing Soils of Hunan Province, China and Potential Health Risks
Published in International journal of environmental research and public health (08-12-2015)“…We studied Cd, Cr, As, Ni, Mn, Pb, and Hg in three agricultural areas of Hunan province and determined the potential non-carcinogenic and carcinogenic risks…”
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Nanoparticles‐induced potential toxicity on human health: Applications, toxicity mechanisms, and evaluation models
Published in MedComm (2020) (01-08-2023)“…Nanoparticles (NPs) have become one of the most popular objects of scientific study during the past decades. However, despite wealth of study reports, still…”
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Association of urinary arsenic with insulin resistance: Cross-sectional analysis of the National Health and Nutrition Examination Survey, 2015–2016
Published in Ecotoxicology and environmental safety (01-02-2022)“…Long-term arsenic exposure is associated with diabetes in adults, the mechanism of which involves insulin resistance. The relationship between arsenic and…”
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A gut dysbiotic microbiota-based hypothesis of human-to-human transmission of non-communicable diseases
Published in The Science of the total environment (25-11-2020)“…Non-communicable diseases (NCDs) have replaced communicable diseases as the leading cause of premature death worldwide over the past century. Increasing…”
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Positive Effect of Probiotics on Constipation in Children: A Systematic Review and Meta-Analysis of Six Randomized Controlled Trials
Published in Frontiers in cellular and infection microbiology (28-04-2017)“…Constipation in children is a prevalent, burdensome, and psychologically important pediatric issue, the treatment of which remains a global challenge. The use…”
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Microglial Activation Damages Dopaminergic Neurons through MMP-2/-9-Mediated Increase of Blood-Brain Barrier Permeability in a Parkinson's Disease Mouse Model
Published in International journal of molecular sciences (03-03-2022)“…Chronic neuroinflammation has been considered to be involved in the progressive dopaminergic neurodegeneration in Parkinson's disease (PD). However, the…”
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Vitamin D, gut microbiota, and radiation-related resistance: a love-hate triangle
Published in Journal of experimental & clinical cancer research (16-12-2019)“…Radiation resistance is a serious issue in radiotherapy. Increasing evidence indicates that the human gut microbiome plays a role in the development of…”
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Probiotics for the Treatment of Atopic Dermatitis in Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Published in Frontiers in cellular and infection microbiology (06-09-2017)“…Atopic dermatitis (AD) is a prevalent, burdensome, and psychologically important pediatric concern. Probiotics have been suggested as a treatment for AD. Some…”
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Inhibition of NADPH oxidase by apocynin prevents learning and memory deficits in a mouse Parkinson's disease model
Published in Redox biology (01-04-2019)“…The activation of NADPH oxidase contributes to dopaminergic neurodegeneration and motor deficits in Parkinson's disease (PD). However, whether NADPH oxidase is…”
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Targeting the gut microbiota by Asian and Western dietary constituents: a new avenue for diabetes
Published in Toxicology research (Cambridge) (01-07-2020)“…Abstract Increasing numerous diabetes annually is a great concern in public health globally. Gut microbiota recently has been suggested to be an emerging organ…”
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Cell density-dependent regulation of microcystin synthetase genes (mcy) expression and microcystin-LR production in Microcystis aeruginosa that mimics quorum sensing
Published in Ecotoxicology and environmental safety (01-09-2021)“…As the secondary metabolites of cyanobacterial harmful algal blooms (Cyano-HABs), microcystins (MCs) were generated under various environmental and cellular…”
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Integrin CD11b mediates locus coeruleus noradrenergic neurodegeneration in a mouse Parkinson's disease model
Published in Journal of neuroinflammation (06-05-2020)“…The loss of locus coeruleus noradrenergic (LC/NE) neurons in the brainstem is reported in multiple neurodegenerative disorders, including Parkinson's disease…”
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Alterations in the gut microbiota of patients with silica-induced pulmonary fibrosis
Published in Journal of occupational medicine and toxicology (London, England) (04-03-2019)“…Silicosis resulting from silica exposure is a global occupational disease characterized by severe pathological changes in progressive pulmonary fibrosis…”
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Lactate exacerbates lung damage induced by nanomicroplastic through the gut microbiota–HIF1a/PTBP1 pathway
Published in Experimental & molecular medicine (01-12-2023)“…Exposure to nanomicroplastics (nano-MPs) can induce lung damage. The gut microbiota is a critical modulator of the gut–lung axis. However, the mechanisms…”
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Meta-analysis on the treatment of diabetic foot ulcers with autologous stem cells
Published in Stem cell research & therapy (16-10-2017)“…Over the last decade, many studies have indicated a therapeutic potential for treating diabetic lower extremity ulcers with autologous stem cells. The aim of…”
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